Bachelor degree



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Module designation


Module 1. General Chemistry and Biochemistry

Biochemistry



Module level, if applicable


Basic professional modules

Code, if applicable


Bio 2404

Subtitle, if applicable


-

Courses, if applicable


Course

Credits

Biochemistry

3




2 lectures + 1 lab / week

Semester(s) in which the module is taught


3 semester

Person responsible for the module


Associate Professor, candidate of Biological Science Goncharova Alla

Lecturer


Associate Professor, candidate of Biological Science Goncharova Alla (Russian department; English department)

Dr., Professor Shoinbekova Sabina (Kazakh department)



Language


Kazakh, Russian, English

Relation to curriculum


Vocational

Type of teaching, contact Hours


Lecture

Practicum

Seminars

30 hours per semester (2 hours per week)

15 hours per semester (1 hours per week)

-

Workload


Lectures

Guided self-study

Self-study

30 hours per semester (2 hours per week)

-

60 hours per semester (4 hours per week)










Credit points


3 credits = 5 ECTS


Requirements according to

the examination regulations


In the process of studying this discipline the students should know: knowledge of the main classes of biological substances (their structure, properties and mechanisms of their functioning), knowledge of the basic metabolic pathways in the body, the relationship of the biological function and molecular structure, the representation of the molecules of nature with biotechnology production.

Recommended prerequisites



Lowmolecular biological substances; Microbiology and Virology

Module objectives/intended

learning outcomes



Knowledge


Skills


Competences


After learning discipline students must:

- remember structure , properties and functions of the main classes of the important biological substances;

- understand the main metabolic pathways in living organisms;

- interactions between biological function and molecular structure of substance;




The students must own:

- skills on the instruments and equipment used in biochemical laboratories;


- modern methods of qualitative and quantitative analysis of nucleic acids, proteins, fats, carbohydrates, vitamins and hormones in biological material

The student should be able:

- to apply the received practical skills and knowledge in various branches of human activity, at performance of the final work;

- to evaluate

experimental data;

- to create the scheme of biochemical experiment according necessary aims.


Content


The course will cover the following topics:

  1. Introduction in Biochemistry.

  2. Proteins. Peculiarities of structure. Classification of proteins. Structural organization of protein.

  3. Enzymes. Structure, mechanism of enzyme action. Kinetics of enzymatic reaction.

  4. Carbohydrates. Classification. Biological significance. Properties of the main representatives.

  5. Lipids. Biological significance, classification. Characteristics of the main classes of lipids. Properties of lipids. Practical using of the main properties of lipids.

  6. Vitamins. Classification. Biological significance. Representatives.

  7. Nucleic acids. Peculiarities of structure. Biological significance. Structural organization of DNA. Types of RNA.

  8. Biosynthesis of Protein. Transcription. Translation.

  9. Basics of metabolism.

  10. Catabolism of proteins. Glucogenic and ketogenic amino acids.

  11. Catabolism of carbohydrates. Glycolysis.

  12. Krebs cycle. Oxidative phosphorylation.

  13. Biosynthesis of glucose.

  14. Metabolism of lipids. Oxidation of fatty acids.

  15. Hormones. Classification. Representatives. Mechanisms of action.

Study and examination

requirements and forms of

examination


1st interim control: oral discussion, testing, , problem solving, testing

2nd interim control: attendance, in-class discussion, problem solving, testing

Final examination: written, 2 theoretical questions, 1 practical question


Media employed


Lectures in presentation form. Video. Animations.

Reading list


  1. Shvedova V.N., Komov B.T. Biochemistry // M., Drofa, 2006. (in russian)

  2. Scherbakov V., Prudnikov. Minakova A.D. Biochemistry // M., GIORD, 2005. (in russian)

  3. Nikolaev A.Y. Biological chemistry // M., 2004. (in russian)

  4. Y. Visual biochemistry.// М., , 2000. (in russian)

  5. Seitov Z.S. Biochemistry, Almaty 2000 (in kazakh)

  6. Beresin I.V., Savin U.V. Basis of biochemistry, 1990. (in russian)

  7. Leninger A .Bases of biochemistry т. 1-3 М., "World" 1986







Module designation


Module 1. General Chemistry and Biochemistry

Lowmolecular biological substances



Module level, if applicable


Basic Professional Modules

Code, if applicable


LBS 1403

Subtitle, if applicable


not applicable

Courses, if applicable


Course

Credits

Lowmolecular biological substances

3




2 lectures + 1 lab / week

Semester(s) in which the module is taught


2 semester

Person responsible for the module


Dr., Professor Beisembaeva R.U.

Lecturer


associate Professor, candidate of Biological Science Orazova S., Professor assistance, candidate of Biological Science Narmuratova M.

Language


Kazakh, Russian, English

Relation to curriculum


(State/Social/ Vocational/IET)

Vocational



Type of teaching, contact Hours


Lecture

Practicum

Seminars

30 hours per semester

2 hours per week



15 hours per semester

1 hour per week




-




Workload


Lectures

Guided self-study

Self-study

30 hours per semester

2 hours per week



-

60 hours per semester

4 hours per week



Credit points


3 credit = 5 ECTS


Requirements according to

the examination regulations


It is necessary to have knowledge of chemistry, language learning, logics and other spheres for studying this course. As one of the tools that fostered an increased understanding of our world, the science of chemistry - the study of matter and the changes it undergoes - developed slowly until near the end of the eighteenth century.

Recommended prerequisites



Chemistry, Physics

Module objectives/intended

learning outcomes



Knowledge


Skills


Competences


Knowledge on the structure, properties and functions of the low-molecular nature of biological compounds that functioning in all organisms.

Remember

The student should remember the basic classification, genetic connection between the classes of compounds, biological value of the main representatives of the low molecular biological molecules.


Understand

The student must to understand the interaction between properties and functions of biomolecular compounds and the structure of their molecules



To get research skills of low-molecular biological compounds in natural objects.

Apply

The student should systematize the knowledge received at studying the course and use them to analyze the results of experimental studies



Analysis

The student should be able to analyze the biological function of the low-molecular compounds on the basis of the structure of the molecule.



To have the theoretical knowledge and be able to
evaluate problems, approaches and trends reflecting the current state of natural compounds
To be able to use them in research and practical applications.

Evaluate

The student should evaluate the possibility of practical application of low-molecular-biological compounds in biotechnology and medicine



Create

The student should create new approaches to the study of biological properties of low-molecular-biological compounds



Content


The low molecular biological molecules derived from natural sources contained carbon, and eventually a new definition of organic chemistry emerged: organic chemistry is the study of carbon compounds.

Classes of low-molecular biological compounds. Aliphatic, carbocyclic and heterocyclic compounds. Structure, properties, function, distribution in nature. Biologically important heterocyclic compounds. Mono-functional and hetero-functional natural compounds structure, chemical properties, and function in the organisms. Natural biologically active compounds, peptides, alkaloids, antibiotics.

Introduction.

Structure determines properties.

Alkanes. Structure and preparation of alkenes:elimination reactions. Reactions of alkenes: addition reactions. Alkynes. Conformations of alkanes and cycloalkanes. Arenes and aromaticity. Hucckel’s rule. Heterocyclic aromatic compounds. Reactions of arenes: electrophilic aromatic substitution.

Alcohols, diols, and thiols. Ethers, epoxides, and sulfides.

Aldehydes and ketones: nucleophilic addition tothe carbonyl group. Enols and enolates

Carboxylic acids. Carboxylic acid derivatives:nucleophilic acyl substitution

. Amines. Phenols. Carbohydrates.

Lipids. Amino acids, peptides, and proteins.

Nucleosides, nucleotides and nucleic acids


Study and examination

requirements and forms of

examination


Written exam, tests

1st interim control: problem solving, testing, case-study

2nd interim control: problem solving, testing, project method

Final examination: written, 1 theoretical questions, 1 exercise,1 practical question



Media employed


Video lectures, Power Point Presentations

Electronic books and scientific journals



Reading list


1. M.L.Belyanin "Biologically active substances of natural origin" Tomsk, Vol. Tomsk Polytechnic Institute, 2010 (in russian)

2. A.A.Semenov Basic Chemistry of Natural Compounds. M., 2009, 1.2 tons (in russian)

3. V.V.Plemenkov "Introduction to the chemistry of natural products," Kazan, 2001 (in russian)



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