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Card 9
1.Read and translate the text:
Brain pattern associated with genetic risk of
OCD
Cambridge researchers have discovered that individuals with obsessive compulsive disorder (OCD) and their close family members have distinctive patterns in their brain structure. This is the first time that scientists have associated an anatomical trait with familial risk for the disorder. These new findings, recently reported in the journal Brain, could help predict whether individuals are at risk of developing OCD and lead to more accurate diagnosis of the disorder. Obsessive compulsive disorder is a prevalent illness that affects 2-3% of the population. OCD patients suffer from obsessions (unwanted, recurrent thoughts, concerns with themes of contamination and 'germs', the need to check household items in case of fire or burglary, the symmetrical order of objects, or fears of harming oneself or others) as well as compulsions (repetitive behaviors related to the obsessions such as washing and carrying out household safety checks). These symptoms can consume the patient's life, causing severe distress, alienation, and anxiety. OCD is known to run in families. However, the complex set of genes underlying this inheritability and exactly how genes contribute to the illness are unknown. Such genes may pose a risk for OCD by influencing brain structure (e.g. the amount and location of grey matter in the brain) which in turn may impact upon an individual's ability to perform mental tasks. In order to explore this idea, the researchers used cognitive and brain measures to determine whether there are biological markers of genetic risk for developing OCD. Using magnetic resonance imaging (MRI), the Cambridge researchers captured pictures of OCD patients' brains, as well as those of healthy close relatives (a sibling, parent, or child) and a group of unrelated healthy people.

Genetika xavfi bilan bog'liq miya naqshlari



OKB

Kembrij tadqiqotchilari obsesif kompulsiv buzuqlik (OKB) bo'lgan shaxslar va ularning yaqin oila a'zolari miya tuzilishida o'ziga xos naqshlarga ega ekanligini aniqladilar. Bu birinchi marta olimlar anatomik xususiyatni buzilish uchun oilaviy xavf bilan bog'lashdi. Yaqinda Brain jurnalida e'lon qilingan ushbu yangi topilmalar odamlarda OKB rivojlanish xavfi mavjudligini va buzilishning aniqroq tashxisiga olib kelishini taxmin qilishga yordam berishi mumkin. Obsesif kompulsiv buzilish keng tarqalgan kasallik bo'lib, aholining 2-3 foiziga ta'sir qiladi. OKB bemorlari obsesyonlardan aziyat chekmoqda (istalmagan, takrorlanadigan fikrlar, ifloslanish mavzusi va "mikroblar", yong'in yoki o'g'rilik paytida uy buyumlarini tekshirish zarurati, ob'ektlarning nosimmetrik tartibi yoki o'ziga yoki boshqalarga zarar etkazishdan qo'rqish). majburlash sifatida (yuvish va uy xavfsizligini tekshirish kabi obsesyonlar bilan bog'liq takrorlanadigan xatti-harakatlar). Ushbu alomatlar bemorning hayotini iste'mol qilishi mumkin, bu esa qattiq qayg'u, begonalashish va xavotirga sabab bo'ladi. OKB oilalarda ishlaydi. Biroq, ushbu merosxo'rlik asosida yotgan murakkab genlar to'plami va genlarning kasallikka qanday hissa qo'shishi aniq emas. Bunday genlar OKB uchun miya tuzilishiga ta'sir qilish orqali xavf tug'dirishi mumkin (masalan, miyada kulrang moddalarning miqdori va joylashishi), bu esa o'z navbatida shaxsning aqliy vazifalarini bajarish qobiliyatiga ta'sir qilishi mumkin. Ushbu g'oyani o'rganish uchun tadqiqotchilar OKBni rivojlantirish uchun genetik xavfning biologik belgilari mavjudligini aniqlash uchun kognitiv va miya o'lchovlaridan foydalandilar. Magnit-rezonans tomografiya (MRG) yordamida Kembrij tadqiqotchilari OKB bemorlari, shuningdek sog'lom yaqin qarindoshlar (aka-uka, ota-ona yoki bola) va o'zaro bog'liq bo'lmagan bir guruh sog'lom odamlarning miyasini suratga olishdi.





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