Bachelor degree

Module designation	Modules of Individual educational direction /traectory (IED) Biotechnology of Antiinfection Solutions Acquiring
Module level, if applicable	IED 1: «Biotechnology of micro-organisms»
Code, if applicable	BASA 3305
Subtitle, if applicable	-
Courses, if applicable	Course		Credits
	Biotechnology of Antiinfection Solutions Acquiring		3
			2 lectures+1 Lab per week
Semester(s) in which the module is taught	6 semester
Person responsible for the module	Dr., Professor Mukasheva T.D.
Lecturer	Dr., Professor Mukasheva T.D., associate Professor, candidate of Biological Science Ignatova L.V., Мukhataeva K.
Language	Kazakh, Russian, English
Relation to curriculum	(State/Social/ Vocational/IET) IET
Type of teaching, contact Hours	Lecture	Practicum		Seminars
	30 hours per semester 2 hours per week	15 hours per semester 1 hour per week		-
Workload	Lectures	Guided self-study		Self-study
	30 hours per semester 2 hours per week	-		60 hours per semester (4 hours per week)
Credit points	3 US credit = 5 ECTS
Requirements according to the examination regulations	50% of overall scores
Recommended prerequisites	BMB 2414 Basics of Microorganisms Biotechnology
Module objectives/intended learning outcomes	Knowledge	Skills		Competences
	Students at the end of the course should know: сlassification of anti-infective drugs; technology of anti-infective drugs; principles of vaccination, chemotherapy, and laboratory diagnosis of infectious diseases.	Must own the: skills in industrial microbiology laboratories; methods of determining the antimicrobial activity of the preparations; methods of microbiological control in the workplace.		Be able to: determine the antimicrobial activity of the preparations; carry out microbiological control in the workplace.
Content	Discipline gives an idea about the basic principles, characteristics, methods of biotechnological production and sanitary-microbiological control of anti-infective drugs, especially of microorganisms that are most important for medicine, the principles of vaccination, chemotherapy, and laboratory diagnosis of infectious diseases. Biotechnology and medicine. The selection of soil microorganisms as objects for the screening of biologically active compounds. The main methods of isolation of microorganisms Вiological objects , as a means of production of medical, preventive and diagnostic tools Improvement of biological objects by methods of mutagenesis and selection Identification and characterization of microorganisms-producers of antibiotics Improvement of biological objects by methods of cell engineering, genetic engineering Cultural and morphological evaluation of grown colonies, isolation of pure cultures of microorganisms with the primary antagonistic activity. The main stages of the biotechnological process. The process of biosynthesis. Classification by technological parameters. Comparison of morphological characteristics of the main producers at a superficial and deep cultivation. The problem of finding, creating and antibiotic use in medical practice. Microbiological methods of determination of antibiotic activity. Preparatory stage. Mechanisms of biosynthesis of antibiotics. Classification mechanisms. Inhibitors of education of cell walls of bacteria. The selection of antibiotics from cultural liquid by thin layer chromatography
Study and examination requirements and forms of examination	Oral exam, tests 1^st interim control: attendance, in-class discussion, problem solving, testing 2^nd interim control: attendance, in-class discussion, problem solving, testing Final examination: written, 2 theoretical questions, 1 practical question
Media employed	Video lectures, Audio books, presentations
Reading list	Gusev M.V., L.A. Mineeva Microbiology. Moscow: Moscow State University Press, 2006. p.5-20. (in russian) Higgins I, Best D., J..Joyce. 1998. Biotechnology: Principles and applications. P. 485. (in english) G. Schlegel General Microbiology. Springer-Verlag, 2005 Netrusov A.I., I.B. Kotova General microbiology. Moscow: Publishing Center "Academy", 2007. (in russian) Shigaeva MH, Chiu WL General microbiology. Almaty. Publ . Kazak university, 2008. 320 Р. (in kazakh) Katalinski A.V. 2003. Medicinal preparations of directed action: the origins and mechanisms of action. P 228. (in russian)