Bachelor degree

Module designation	Modules of Individual educational direction /traectory (IED) Microbial control of biotechnology production
Module level, if applicable	IED 1: «Biotechnology of microorganisms»
Code, if applicable	MCBP 3306
Subtitle, if applicable	-
Courses, if applicable	Course		Credits
	Microbial control of biotechnology production		3
			2 lectures+1 Lab per week
Semester(s) in which the module is taught	6 semester
Person responsible for the module	Dr., Professor Savitskaya I.S.
Lecturer	Dr., Professor Savitskaya I.S. associate Professor, candidate of Biological Science Berzhanova R.Zh.
Language	Kazakh, Russian, English
Relation to curriculum	(State/Social/ Vocational/IET) IET
Type of teaching, contact Hours	Lecture	Practicum		Seminars
	30 hours per semester 2 hours per week	15 hours per semester 1 hour per week		-
Workload	Lectures	Guided self-study		Self-study
	30 hours per semester 2 hours per week	-		60 hours per semester (4 hours per week)
Credit points	3 credit = 5 ECTS
Requirements according to the examination regulations	50% of overall scores
Recommended prerequisites	BMB 2414 Basics of Microorganisms Biotechnology
Module objectives/intended learning outcomes	Knowledge	Skills		Competences
	Students at the end of the course should know: micro-contaminants biotechnology industries; sanitary indicative microorganisms; hygiene requirements for production facilities and manufacturing processes.	-Must own the:ways to ensure the sterility of the microbiological production; skills in the microbiological analysis of food production; methods of determining the producers in the working area; methods of determining the sanitary-indicative microorganisms in biotechnology products and equipment.		Be able to: identify microorganisms contaminants; determine the titer of sanitary-indicative microorganisms in products and equipment; identify producers in the working area; use of risk analysis in the process of food production.
Content	The course provides the knowledge about the safety of biotechnological production of food raw materials and food products. The characteristics of microbial contaminants major biotech industries and sanitary-indicative microorganisms. The role of microflora in the water, air and soil in the spread of infectious diseases and food contamination by foreign microorganisms. Provides an overview of the methods of preservation, sterilization and disinfection used in the food industry. Some sections of the course include how to ensure the sterility of microbial production, sanitary and hygienic requirements for production facilities and manufacturing processes, risk analysis system and their applicability in the production of food.
Study and examination requirements and forms of examination	Oral exam, tests 1^st interim control: attendance, in-class discussion, problem solving, testing 2^nd interim control: attendance, in-class discussion, problem solving, testing Final examination: written, 2 theoretical questions, 1 practical question Intermediate control of knowledge: control work (in written form), colloquium (in oral form) and test
Media employed	Video lectures, Audio books, presentations
Reading list	Rogov I.A., Dunchenko N.I., Poznyakovsky V.M., Berdutina A.V., Kuptsova S.V. Safety of food raw materials and food products. Novosibirsk, 2007 (in russian) Dunchenko N.I., Khramtsov A.G., Makeev I.A., etc. Expertise of food and raw food. Milk and dairy raw materials. Novosibirsk 2007 (in russian) Rogozhin V.V., Rogozhina T.V. Practical work on biochemistry of milk and dairy products. St. Petersburg, 2008 (in russian) G. Schlegel General Microbiology. Springer-Verlag, 2005. (in english) Shigaeva MH, Chiu WL General microbiology. Almaty. Publ . Kazak university, 2008. 320 Р. (in english)

Module designation	Modules of Individual educational direction /traectory (IED) Probiotics
Module level, if applicable	IED 1: «Biotechnology of microorganisms»
Code, if applicable	Р 4307
Subtitle, if applicable	-
Courses, if applicable	Course		Credits
	Probiotics		3
			2 lectures+1 Lab
Semester(s) in which the module is taught	7 semester
Person responsible for the module	Dr., Professor Savitskaya I.S.
Lecturer	Dr., Professor Savitskaya I.S. associate Professor, candidate of Biological Science Kistaubaeva A.S.
Language	Kazakh, Russian, English
Relation to curriculum	(State/Social/ Vocational/IET) IET
Type of teaching, contact Hours	Lecture	Practicum		Seminars
	30 hours per semester 2 hours per week	15 hours per semester 1 hour per week		-
Workload	Lectures	Guided self-study		Self-study
	30 hours per semester 2 hours per week	-		60 hours per semester (4 hours per week)
Credit points	3 US credit = 5 ECTS
Requirements according to the examination regulations	50% of overall scores
Recommended prerequisites	BMB 2414 Basics of Microorganisms Biotechnology
Module objectives/intended learning outcomes	Knowledge	Skills		Competences
	Students at the end of the course should know: microbial ecology of the human body; composition of the normal flora of different habitats; function of normal microflora; causes of and ways of correcting dysbacterioses; classification of probiotics; technology of probiotics.	Must own the: skills of the bacteriological analysis of the intestinal microflora; methods of isolation and identification of probiotics; methods for determining acid-active probiotics. methods of determining the antimicrobial activity of probiotics.		Be able to:make microbial passport; - determine the titer of bacteria in probiotics; identify lactobacilli and bifidobacteria by culture and morphological characteristics;determine the acid-forming and antimicrobial activity of probiotics.
Content	The course provides insight into the preparations of probiotics, prebiotics and synbiotics are considered metabolite, lactulose and combination probiotic drugs, their mechanisms of therapeutic effect.The problem of creating new bacterial preparations that are created on the basis of probiotic bacteria synthesizing antibiotic like substance - microcins with a broad spectrum of bactericidal action. During the course students get acquainted with the technology of probiotics.
Study and examination requirements and forms of examination	Oral exam, tests 1^st interim control: attendance, in-class discussion, problem solving, testing 2^nd interim control: attendance, in-class discussion, problem solving, testing Final examination: written, 2 theoretical questions, 1 practical question Intermediate control of knowledge: control work (in written form), colloquium (in oral form) and test
Media employed	Video lectures, Audio books, presentations
Reading list	Shigaeva MH, Chiu WL General microbiology. Almaty. Publ . Kazak university, 2008. 320 Р. (in kazakh) Seitov Z.S. Biochemistry, Almaty 2000 (in kazakh) Gusev M.V., L.A. Mineeva Microbiology. Moscow: Moscow State University Press, 2006. p.5-20. (in russian) G. Schlegel General Microbiology. Springer-Verlag, 2005. (in english) Modern microbiology. Prokaryotes (in 2 volumes). Ed. G. Drevsa, G. Shlegel etc. Academic Press, 2005. (in english)

Module designation	Modules of Individual educational direction /traectory (IED) Immobilized microbial cells
Module level, if applicable	IED 1: «Biotechnology of microorganisms»
Code, if applicable	ICM 4308
Subtitle, if applicable	-
Courses, if applicable	Course		Credits
	Immobilized microbial cells		3
			2 lectures + 1 lab / week
Semester(s) in which the module is taught	7 semester
Person responsible for the module	Dr., Professor Zhubanova A.A.
Lecturer	Dr., Professor Zhubanova A.A., associate Professor, candidate of Biological Science Gulzhan K. Kaiyrmanova
Language	Kazakh, Russian, English
Relation to curriculum	(State/Social/ Vocational/IET) IET
Type of teaching, contact Hours	Lecture	Practicum		Seminars
	30 hours per semester 2 hours per week	15 hours per semester 1 hour per week		-
Workload	Lectures	Guided self-study		Self-study
	30 hours per semester 2 hours per week			60 hours per semester 4 hours per week
Credit points	3 credit = 5 ECTS
Requirements according to the examination regulations	50% of overall scores Students should know the basics of enzymology, biotechnology and biotechnology of microorganisms.
Recommended prerequisites	BMB 2414 Basics of Microorganisms Biotechnology
Module objectives/intended learning outcomes	Knowledge	Skills		Competences
	Knowledge: development of the students the basic principles and theoretical positions Enzyme Engineering, to help students understanding of biotechnological processes involving enzymes, mastering the fundamentals of design and use in biotechnology biocatalysts with desired properties. Remember Remember features of physiology and cell biology of microorganisms in relation to their use in various fields of biotechnology Understand understand the benefits of immobilized microorganisms when used in various branches of biotechnology	The student should know physico-chemical and biochemical patterns of biocatalysis; methods of stabilization and recovery of enzymatic systems used in biotechnology; examples of the use of free and immobilized biocatalysts based on enzymes and microbial cells in science, medicine, technology and industry. Apply Apply basic patterns of functioning, methods of stabilization and activation for active immobilized cells of microorganisms used in biotechnology. Analysis analyze the features of of biotechnological processes involving immobilized cells of microorganisms		Competences possession of methods of observation, description, classification, cultivation immobilized biological objects (enzymes and microbial cells, ability to apply basic physiological methods of analysis and assessment of heterogeneous biocatalizators, current understanding of the principles of immobilization of biological objects, biophysical-cal and biochemical basis, the nature of different sorbents and carriers. Evaluate Аssess advantages and economic justification of the use of free or immobilized biocatalysis for various biotechnological processes. Create Create specific research, information retrieval, methodical tasks for active immobilized cells of microorganisms
Content	Fundamental and applied aspects of Enzyme Engineering. Structure, properties and mechanism of action of biocatalysts. The similarity and difference of the synthetic biological catalysts. Advantages and disadvantages of biocatalysis in its use in industrial processes. The course will cover the following topics: Value cell immobilization for the development of the biotechnology industry. Basic methods of immobilization of cells of microorganisms. Immobilization processes , adhesion, adsorption of biological objects. Carriers for immobilization of enzymes and whole cells , their characteristics. Requirements for carriers. Advantages and disadvantages of the immobilized microbial cells and enzymes in biotechnological processes. Criteria for selecting the method of immobilization Industrial processes using immobilized microbial cells. Use of immobilized cells for the disposal of solid and liquid waste
Study and examination requirements and forms of examination	Oral exam, tests 1^st interim control: attendance, in-class discussion, problem solving, testing 2^nd interim control: attendance, in-class discussion, problem solving, testing Final examination: written, 2 theoretical questions, 1 practical question
Media employed	Video lectures, Audio books, presentations
Reading list	Zhubanova A.A., Abdieva G.ZH., Shupshibaev K.K. Basics of Microorganismes Biotechnology. Almaty, 2004. (in russian, in kazakh) Nechaev A.P. Food Chemistry. St. Petersburg, 2007 (in russian) Drozdova T.M., Vlyuschensky P.B., Poznyakovsky V.M. Physiology of nutrition. Novosibirsk 2007 (in russian) Cavicchioli, R., and Thomas, T. 2000. Extremophiles. In Encyclopedia of microbiology, 2d ed., vol. 2, J. Lederburg, editor-in-chief. - P. 317–337. San Diego: Academic Press. (in english)