Karlstrom, Amelie and Nygren, Per-Ake (2001). Dual Labeling of a Binding Protein Allows for Specific Fluorescence Detection of Native Protein. Analytical Biochemistry 295: 22-30.
Chem Codes: Chemical of Concern: DZ Rejection Code: METHODS.
Fluorescence resonance energy transfer has been investigated in the context of specific detection of unlabeled proteins. A model system based on the staphylococcal protein A (SPA)-IgG interaction was designed, in which a single domain was engineered to facilitate site-specific incorporation of fluorophores. An Asn23Cys mutant of the B domain from SPA was expressed in Escherichia coli and subsequently labeled at the introduced unique thiol and at an amino group, using N-iodoacetyl-N′-(5-sulfo-1-naphthyl)ethylenediamine (1,5-IAEDANS) and succinimidyl 6-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)hexanoate (NBD-X, SE), respectively. Biosensor analysis of purified doubly labeled protein showed that high-affinity binding to the Fc region of IgG was retained. The fluorescence emission spectrum of the doubly labeled protein showed a shift in the relative emission of the two fluorophores in the presence of Fc3(1) fragments, which bind specifically to the B domain. In addition, the fluorescence emission ratio 480/525 nm was shown to increase with increasing concentration of Fc3(1), whereas the presence of a control protein did not affect the emission ratio over the same concentration range. biosensor/ fluorescent labeling/ fluorescence resonance energy transfer/ protein engineering/ staphylococcal protein A/ affibody
Karsouh, A. S. H. and Hopkins, T. L. (1968). Diazinon Absorption, Translocation, and Metabolism in Bean Plants. J.Agric.Food Chem. 16: 446-450.
EcoReference No.: 72817
Chemical of Concern: DZ; Habitat: T; Effect Codes: ACC; Rejection Code: NO ENDPOINT(DZ).
KASHEM MA and MIAN AJ (1993). Rice husk as a carrier for granular pesticides. DHAKA UNIV STUD PART B SCI; 41 103-106.
Chem Codes: Chemical of Concern: DZ Rejection Code: METHODS.
BIOSIS COPYRIGHT: BIOL ABS. Rice husks of the high yielding varieties are primarily composed or organic matters. n-Hexane treated rice husk on formulations with diazinon for granular pesticides indicated about 98% efficacy having satisfactory heat and chemical stability. Biochemistry/ Cereals/ Plants/Growth & Development/ Soil/ Herbicides/ Pest Control/ Pesticides/ Grasses
Kasiotis, Konstantinos M., Mendorou, Christina, Haroutounian, Serkos A., and Alexis, Michael N. (2006). High affinity 17[alpha]-substituted estradiol derivatives: Synthesis and evaluation of estrogen receptor agonist activity. Steroids 71: 249-255.
Chem Codes: Chemical of Concern: DZ Rejection Code: METHODS.
We synthesized four derivatives of 17[beta]-estradiol (E2) with an azide substitution on a 17[alpha]-side chain of varying length, namely 17[alpha]-(azidopropargyl)-3,17[beta]-estradiol (5), its 17[beta]-azido derivative (diazide 7), 17[alpha]-(5-azido-pent-1-ynyl)-3,17[beta]-estradiol (6) and 17[alpha]-(azidopentyn-2-yl)-3,17[beta]-estradiol (10). While most of the derivatives had low (7) or marginal (6 and 10) relative binding affinity (RBA) for both types of estrogen receptor (ER[alpha] and ER[beta]), the RBA[alpha] and RBA[beta] of 5 were practically identical to those of E2. The estrogenic activity of the derivatives was assessed using estrogen-responsive breast (MCF-7) and endometrial cancer (Ishikawa) cells. While 5 was a potent and effective inducer of alkaline phosphatase in Ishikawa cells and 7 was less potent but as effective as 5, 6 was marginally active and 10 was totally inactive in this respect. In the presence of 0.1 nM E2, however, 6 exhibited some ER antagonist activity at the highest concentration tested (1 [mu]M). Similar results were obtained as regards the potency and efficacy of stimulation of MCF-7 cell proliferation and induction of luciferase gene expression in MCF-7:D5L cells, a clone stably transfected with an estrogen-responsive form of the gene. These data suggest that, while 5, 6, 7 and 10 interact with either type of ER in isolation, only 5 and 7 exhibit substantial ER agonist activity in the different estrogen-target cells examined, which could provide for photoaffinity labelling of the receptor in the cell as well as in isolation. 17[alpha]-Alkynylazido estradiol derivatives/ Estrogenic activity
KATAYAMA, A. and KUWATSUKA, S. (1991). Effect of pesticides on cellulose degradation in soil under upland and flooded conditions.
Chem Codes: Chemical of Concern: DZ Rejection Code: FATE.
BIOSIS COPYRIGHT: BIOL ABS. The effect of pesticides on cellulose degradation in a soil was estimated by incubation experiments under upland conditions, transitional flooded conditions from aerobic to anaerobic, and fully anaerobic flooded conditions. Pesticides examined were trichlamide ((RS)-N-(1-butoxy-2,2,2-trichloroethyl)salicylamide), chlorothalonil (TPN, 2,4,5,6-tetrachloro-1,3-isophthalonitrile), quintozene (PCNB, pentachloronitrobenzene), and hymexazol (3-hydroxy-5-methylisoxazol) as fungicides, paraquat (1,1'-dimethyl-4,4'-bipyridium dichloride), thiobencarb (benthiocarb, S-p-chlorobenzyldiethyl thiocarbamate), propanil (DCPA, 3',4'-dichloropropionanilide), and butachlor (2-chloro-2',6'-diethyl-N-(butoxymethyl)acetoanilide) as herbicides, and diazinon (2-isopropyl-4-methylpyrimidyl-6-diethylthiophosphate) as insecticide. Trichlamine inhibited completely the cellulose degradation under the tow flooded conditions, while the inhibition under upland conditions was weak. The inhibition by chl Biochemistry/ Carbohydrates/ Biophysics/ Plants/Chemistry/ Grasses/Growth & Development/ Soil/ Soil/ Herbicides/ Pest Control/ Pesticides
KATHEIN, R. (1986). THE DEVELOPMENT OF POULTRY SLAUGHTER AND POULTRY MEAT INSPECTION IN ISRAEL A REVIEW. ISR J VET MED; 42 146-157.
Chem Codes: Chemical of Concern: DZ Rejection Code: NO TOX DATA.
BIOSIS COPYRIGHT: BIOL ABS. RRM BACTERIAL CONTAMINATION TOXIC FOOD RESIDUES VETERINARY INSPECTION REGULATION GOVERNMENT Legislation/ Organization and Administration/ Biology/ Eggs/ Food Technology/ Poultry/ Food Analysis/ Food Technology/ Food-Processing Industry/ Food Technology/ Food Additives/Poisoning/ Food Additives/Toxicity/ Food Contamination/ Food Poisoning/ Food Preservatives/Poisoning/ Food Preservatives/Toxicity/ Animal Husbandry/ Poultry/ Veterinary Medicine/ Animal Diseases/Pathology/ Animal Diseases/Physiopathology/ Food Microbiology/ Food Contamination/ Beverages/ Industrial Microbiology
Kato, T., Ogiso, T., Kato, K., Sano, M., Hasegawa, R., Shirai, T., and Ito, N. (1995). Lack of promoting activity of four pesticides on induction of preneoplastic liver cell foci in rats. Teratogenesis, Carcinogenesis and Mutagenesis [TERATOG. CARCINOG. MUTAG.]. Vol. 15, no. 5, pp. 251-257. 1995.
Chem Codes: Chemical of Concern: DZ Rejection Code: MIXTURE.
ISSN: 0270-3211
Descriptors: pesticides
Descriptors: carcinogenesis
Descriptors: liver
Descriptors: preneoplasia
Abstract: Four pesticides were examined for hepatopromoting activity using a medium-term bioassay based upon induction of glutathione S-transferase placental form (GST-P) positive foci in the rat liver. Male F344 rats were initially injected with diethylnitrosamine (DEN; 200 mg/kg body weight) intraperitoneally and 2 weeks later were treated with O-ethyl O-4-nitrophenyl phenylphosphonothioate (EPN; 75 and 150 ppm), diazinon (500 and 1,000 ppm), phenthoate (500 and 1,000 ppm), or iprobenfos (500 and 1,000 ppm) in the diet for 6 weeks and then killed, all rats being subjected to partial hepatectomy at week 3. All of the pesticides gave negative results, the numbers and areas of GST-P positive foci not exceeding the control values for animals given DEN alone. Indeed, a significant reduction of foci development was seen for EPN (75 ppm). These findings provide experimental evidence that the presently examined four pesticides do not have hepatocarcinogenic potential in rats.
Publisher: JOHN WILEY & SONS
Language: English
English
Publication Type: Journal Article
Classification: X 24134 Pathology
Subfile: Toxicology Abstracts
Katragadda, Suresh, Talluri, Ravi S., and Mitra, Ashim K. ( Simultaneous modulation of transport and metabolism of acyclovir prodrugs across rabbit cornea: An approach involving enzyme inhibitors. International Journal of Pharmaceutics In Press, Corrected Proof.
Chem Codes: Chemical of Concern: DZ Rejection Code: HUMAN HEALTH.
Enzyme inhibitors/ Corneal hydrolysis/ Prodrugs/ Transporters/ Hydrolytic enzymes The aim of this study is to identify the class of enzymes responsible for the hydrolysis of amino acid and dipeptide prodrugs of acyclovir (ACV) and to modulate transport and metabolism of amino acid and dipeptide prodrugs of acyclovir by enzyme inhibitors across rabbit cornea. l-Valine ester of acyclovir, valacyclovir (VACV) and l-glycine-valine ester of acyclovir, gly-val-acyclovir (GVACV) were used as model compounds. Hydrolysis studies of VACV and GVACV in corneal homogenate were conducted in presence of various enzyme inhibitors. IC50 values were determined for the enzyme inhibitors. Transport studies were conducted with isolated rabbit corneas at 34 [deg]C. Complete inhibition of VACV hydrolysis was observed in the presence of Pefabloc SC (4-(2-aminoethyl)-benzenesulfonyl-fluoride) and PCMB (p-chloromercuribenzoic acid). Similar trend was also observed with GVACV in the presence of bestatin. IC50 values of PCMB and bestatin for VACV and GVACV were found to be 3.81 [plus-or-minus sign] 0.94 and 0.34 [plus-or-minus sign] 0.08 [mu]M respectively. Eserine, tetraethyl pyrophosphate (TEPP) and diisopropyl fluorophosphate (DFP) also produced significant inhibition of VACV hydrolysis. Transport of VACV and GVACV across cornea showed decreased metabolic rate and modulation of transport in presence of PCMB and bestain respectively. The principle enzyme classes responsible for the hydrolysis of VACV and GVACV were carboxylesterases and aminopeptidases respectively. Enzyme inhibitors modulated the transport and metabolism of prodrugs simultaneously even though their affinity towards prodrugs was distinct. In conclusion, utility of enzyme inhibitors to modulate transport and metabolism of prodrugs appears to be promising strategy for enhancing drug transport across cornea.
Kaufman, D. D. (1977). Biodegradation and persistence of several acetamide, acylanilide, azide, carbamate, and organophosphate pesticide combinations. Soil Biology and Biochemistry 9: 49-57.
Chem Codes: Chemical of Concern: DZ Rejection Code: FATE.
The effect of potassium azide (KN3), O,O-diethyl O-(2-isopropyl-6-methyl-4-pyrimidinyl) phosphorothioate (diazinon), O,O-diethyl S-[(ethylthio)- methyl] phosphorodithioate (phorate), 1-naphthyl methylcarbamate (carbaryl), and p-chlorophenyl methylcarbamate (PCMC) on the biodegradation and persistence of several amide, carbamate, and urea herbicides in soil and microbial culture systems was examined. KN3 inhibited the biodegration of isopropyi m-chlorocarbanilate (chlorpropham) in both soil perfusion and microbial culture system, but was limited in increasing chlorpropham persistence in soil under greenhouse conditions. PCMC and diazinon, inhibited the metabolism of chlorpropham by isolated cultures of soil bacteria (Pseudonwnas striata Chester and Achromobacter sp). Phorate inhibited chlorpropham metabolism by P. striata, but did not inhibit chlorpropham metabolism by Achromobacter sp. Carbaryl, PCMC, and diazinon increased the persistence of chlorpropham in soil under greenhouse conditions. PCMC also inhibited the microbial metabolism of isopropyl carbanilate (propham), 3',4'-dichloropropionanilide (propanil), 2-chloro-N,N-diallylacetamide (CDAA), 1,1-dimethyl-3 ([alpha],ga,[alpha]-trifluoro-m-tolyl)urea (fluometuron) and 3-(3,4-dichlorophenyl)-1,1-dimethylurea (diuron), but not that of 2-chloro-N-isopropylacetanilide (propachlor) in isolated culture systems.
Kawai, S., Fukushima, M., Tsuchinaga, T., and Oda, K. (1984). Metals and Synthetic Organic Compounds in Plankton from the Estuary and Harbor Area in Osaka City. Bull.Jpn.Soc.Sci.Fish.(Nippon Suisan Gakkaishi) 50: 1777-1783.
Chem Codes: EcoReference No.: 10820
Chemical of Concern: DZ Rejection Code: NO DURATION/SURVEY.
KAWATA, K., MUKAI, H., TANABE, H., and YASUHARA, A. (1996). ANNUAL VARIATION OF INSECTICIDES IN PRECIPITATION IN RURAL JAPAN. BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY; 57 853-858.
Chem Codes: Chemical of Concern: DZ Rejection Code: SURVEY.
BIOSIS COPYRIGHT: BIOL ABS. RRM RESEARCH ARTICLE ATMOSPHERIC INSECTICIDES ANNUAL VARIATION PRECIPITATION POLLUTION CLIMATOLOGY RURAL AREA NIIGATA PREFECTURE JAPAN Climate/ Ecology/ Meteorological Factors/ Air Pollution/ Soil Pollutants/ Water Pollution/ Herbicides/ Pest Control/ Pesticides
Keizer, J., D' Agostino, G., Nagel, R., Volpe, T., Gnemi, P., and Vittozzi, L. (1995). Enzymological Differences of AChE and Diazinon Hepatic Metabolism: Correlation of In Vitro Data with the Selective Toxicity of Diazinon to Fish Species. Sci.Total Environ. 171: 213-220.
Chem Codes: EcoReference No.: 45859
Chemical of Concern: DZ Rejection Code: IN VITRO/METABOLISM.
Keizer, J., D'Agostino, G., Nagel, R., Volpe, T., Gnemi, P., Vittozzi, L. *., and Vittozzi, L. (ed) (1995). Enzymological differences of AChE and diazinon hepatic metabolism: Correlation of in vitro data with the selective toxicity of diazinon to fish species.
Chem Codes: Chemical of Concern: DZ Rejection Code: IN VITRO.
ISSN: 0048-9697
Descriptors: pesticides
Descriptors: insecticides
Descriptors: liver
Descriptors: metabolism
Descriptors: toxicity
Descriptors: enzymes
Descriptors: enzymatic activity
Descriptors: neurotransmitters
Descriptors: toxicology
Descriptors: pollution effects
Descriptors: diazinon
Descriptors: fish
Descriptors: enzyme inhibitors
Descriptors: comparative studies
Descriptors: Oncorhynchus mykiss
Descriptors: Poecilia reticulata
Descriptors: Danio rerio
Descriptors: Cyprinus carpio
Abstract: The in vitro hepatic metabolism of diazinon, as well as the sensitivity of the brain acetylcholine esterase, to diazoxon inhibitory action have been studied in order to explain the different toxicity of diazinon to Oncorhynchus mykiss (rainbow trout), Poecilia reticulata (guppy), Brachydanio rerio (zebra fish) and Cyprinus carpio (carp). In spite of a very sensitive acetylcholine esterase the carp is very resistant to diazinon toxicity because of its very low rate of bioactivation and relatively high activity of detoxicating enzymes. The trout is very sensitive towards diazinon in spite of its low activity of bioactivation, because of its lack of detoxicating enzymes and a very sensitive acetylcholine esterase. Diazinon is very toxic for the guppy, because this fish combines a relatively sensitive acetylcholine esterase with a high rate of bioactivation. The zebra fish has the most insensitive acetylcholine esterase, associated with a limited activation rate, thus resulting a rather resistant species. The results obtained indicate that diazinon toxicity differences among the fish species studied can largely be explained in relation to metabolic balances in the liver and with the features of the target enzyme.
Conference: Regional Meeting of the Society of Ecotoxicology and Environmental Safety, Rome (Italy), 26-29 Sep 1993
Language: English
English
Publication Type: Book Monograph
Publication Type: Conference
Environmental Regime: Freshwater
Classification: X 24135 Biochemistry
Classification: P 6000 TOXICOLOGY AND HEALTH
Classification: SW 3030 Effects of pollution
Classification: Q5 01504 Effects on organisms
Subfile: ASFA 3: Aquatic Pollution & Environmental Quality; Water Resources Abstracts; Pollution Abstracts; Toxicology Abstracts
Kelch, W. J. and New, J. C. Jr. (1993). The Reported Use of Drugs to Prevent Diseases in Beef Cattle in Tennessee. Prev.Vet.Med. 15: 291-302.
EcoReference No.: 76627
Chemical of Concern: CYP,PYT,PMR,FYT,PSM,MXC,MLN,FNTH,DDVP,DZ,CMPH; Habitat: T; Effect Codes: PHY; Rejection Code: NO ENDPOINT,CONTROL(ALL CHEMS).
Kenaga, E. E. (1982). Predictability of Chronic Toxicity from Acute Toxicity of Chemicals in Fish and Aquatic Invertebrates. Environ.Toxicol.Chem. 1: 347-358.
Chem Codes: EcoReference No.: 45649
Chemical of Concern: DZ Rejection Code: REFS CHECKED/REVIEW.
Kenaga, E. F. (1979). Aquatic Test Organisms and Methods Useful for Assessment of Chronic Toxicity of Chemicals. In: K.L.Dickson, A.W.Maki, and J.Cairns,Jr.(Eds.), Analyzing the Hazard Evaluation Process, Am.Fish.Soc. 101-111.
Chem Codes: EcoReference No.: 64340
Chemical of Concern: DZ Rejection Code: METHODS/REVIEW.
Kendall, T. J., Brewer, L. W., Hitchcock, R. R., and Mayer, J. R. (1992). American Wigeon Mortality Associated with Turf Application of Diazinon AG500. J.Wild.Dis. 28: 263-267.
EcoReference No.: 85643
Chemical of Concern: DZ; Habitat: T; Effect Codes: MOR,BCM,ACC; Rejection Code: NO ENDPOINT(DZ).
Keplinger, M. L. and Deichmann, William B. (1967). Acute toxicity of combinations of pesticides. Toxicology and Applied Pharmacology 10: 586-595.
Chem Codes: Chemical of Concern: DZ Rejection Code: MIXTURE.
The acute oral toxicity (LD50) of equitoxic doses of combinations of 15 pesticides was determined in rats and mice. The Expected LD50 of a “mixture” was compared with the Observed or Actual LD50 and expressed as a ratio. The compounds studied included the chlorinated hydrocarbons aldrin, Aramite, chlordane, DDT, dieldrin, endrin, methoxychlor, and toxaphene; the organic phosphates Delnav, diazinon, malathion, parathion, trithion, and V-C 13; and a carbamate, carbaryl.Most of the combinations of two or three of these pesticides induced essentially additive effects in both species, with the exception of the combination of aldrin and chlordane. These two compounds induced an additive effect in rats, while in mice there was a potentiation.Less than additive effects (antagonism or protection) were noted with: aldrin plus diazinon, malathion, V-C 13, Delnav, or trithion (rat); DDT plus malathion, V-C 13, or diazinon (rat); toxaphene plus trithion (rat); endrin plus DDT or Delnav (mouse); and aldrin plus parathion (mouse).More than additive effects (possibly some degree of potentiation) were noted with: endrin plus chlordane or aldrin (mouse); Aramite plus Delnav, diazinon, or parathion (mouse); methoxychlor plus chlordane, dieldrin or Delnav (mouse); aldrin plus chlordane (mouse); and chlordane plus parathion plus malathion (mouse).The data in the combinations of three pesticides did not reveal effects of toxicity which could not have been predicted from the combinations of two compounds.
Keren-Zur, Mordechai, Beigel, Michael, and Loyter, Abraham (1989). Induction of fusion in aggregated and nonaggregated liposomes bearing cationic detergents. Biochimica et Biophysica Acta (BBA) - Biomembranes 983: 253-258.
Chem Codes: Chemical of Concern: DZ Rejection Code: METHODS.
The addition of polyanionic polymers such as poly(aspartic acid) (PASP), DNA or dextran sulfate to liposomes composed of phosphatidylcholine (PC) and cholesterol (chol), and bearing the quaternary ammonium detergent [[[(1,1,3,3-tetramethylbutyl)cresoxy]ethoxy]ethyl]dimethylbenzylammonium hydroxide (DEBDA]OH]) resulted in liposome aggregation and fusion. Liposome-liposome fusion was studied by using fluorescently labeled liposomes and fluorescence-dequenching (DQ) methods. Addition of monoanions, such as aspartate or acetate, to liposomes bearing DEBDA[OH] caused neither their aggregation nor liposome-liposome fusion. Aggregation of liposomes bearing DEBDA[OH] by the binding pair avidin-biotin did not result in their fusion. Fusion in such aggregated liposomes was observed by the addition of chaotropic anions, such as nitrate or thiocynate, or by PASP. A variety of other quaternary ammonium detergents behaved similarly to DEBDA[OH] in their ability to confer fusogenic properties upon PC/chol liposomes. The relevance of these findings to the mechanism of liposome-liposome fusion is discussed. Liposome fusion/ Cationic detergent/ Biotin/ Avidin/ Chaotropic ion/ Fluorescence energy transfer
KERTESZ MA, COOK AM, and LEISINGER, T. (1994). MICROBIAL METABOLISM OF SULFUR-AND PHOSPHORUS-CONTAINING XENOBIOTICS. FEMS MICROBIOLOGY REVIEWS; 15 195-215.
Chem Codes: Chemical of Concern: DZ Rejection Code: BACTERIA.
BIOSIS COPYRIGHT: BIOL ABS. RRM LITERATURE REVIEW BACTERIA ENZYME CHARACTERIZATION GENETIC ANALYSIS REGULATION Biochemistry/ Minerals/ Enzymes/Physiology/ Metabolism/ Minerals/Metabolism/ Bacteria/Physiology/ Bacteria/Metabolism/ Bacteria/Genetics/ Viruses/Genetics/ Biodegradation/ Industrial Microbiology/ Bacteria
Key, P. B., Fulton, M. H., Harman Fetcho, J. A., and McConnell, L. L. (2003). Acetylcholinesterase Activity in Grass Shrimp and Aqueous Pesticide Levels from South Florida Drainage Canals. Archives of Environmental Contamination and Toxicology [Arch. Environ. Contam. Toxicol.]. Vol. 45, no. 3, pp. 371-377. Oct 2003.
Chem Codes: Chemical of Concern: DZ Rejection Code: SURVEY.
ISSN: 0090-4341
Descriptors: Canals
Descriptors: Pesticides
Descriptors: Acetylcholinesterase
Descriptors: Runoff
Descriptors: Drainage
Descriptors: Insecticides
Descriptors: Metolachlor
Descriptors: Land use
Descriptors: Atrazine
Descriptors: Water conservation
Descriptors: Diazinon
Descriptors: Surface water
Descriptors: Contamination
Descriptors: Malathion
Descriptors: organophosphates
Descriptors: Fresh water
Descriptors: Chlorpyrifos
Descriptors: Penaeidae
Descriptors: Palaemonetes intermedius
Descriptors: USA, Florida
Abstract: Freshwater drainage canals in South Florida are utilized to manage water in agricultural, urban, and water conservation areas and, as a result, collect urban and agricultural storm runoff that is discharged into the Atlantic Ocean and Gulf of Mexico. Pesticides in this runoff may be toxic to the biota inhabiting these waters. This study evaluated the effects of contaminants in South Florida canals draining into Biscayne Bay on the estuarine grass shrimp (Palaemonetes intermedius), a representative invertebrate species. Results of surface water analysis for pesticides indicated that eight pesticides out of 52 analyzed were detected. The herbicide metolachlor was found at all nine sites in the five canals sampled at concentrations up to 119 ng/L. Atrazine was detected at seven sites at concentrations up to 29 ng/L. Three organophosphate insecticides (chlorpyrifos, malathion, diazinon) were detected at three sites in two canals (Military and North). Grass shrimp from these three sites showed significantly reduced levels of the acetylcholinesterase enzyme as compared to control shrimp. These two canals are similar in the land use areas drained-urban and suburban and agriculture. The results suggest that monitoring organisms for AChE levels can be a means of detecting exposure to organophosphorus pesticide contamination.
Publisher: Springer-Verlag
DOI: 10.1007/s00244-003-0173-7
Language: English
English
Publication Type: Journal Article
Classification: X 24136 Environmental impact
Classification: P 2000 FRESHWATER POLLUTION
Classification: EE 40 Water Pollution: Monitoring, Control & Remediation
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