Smallpox Presentation


Clinical Forms of Smallpox



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Clinical Forms of Smallpox

  • Center for Food Security and Public Health Iowa State University - 2004
  • Variola major
    • Most common and severe form
    • Extensive rash, higher fever
    • Ordinary (discrete, confluent, semi-confluent)
    • Modified
    • Flat
    • Hemorrhagic (early and late)
  • Variola minor
    • Less common, less severe disease

Variola Major

  • Center for Food Security and Public Health Iowa State University - 2004

Variola Major

  • Center for Food Security and Public Health Iowa State University - 2004
  • Semi-Confluent
    • Pustules begin to merge
  • Confluent
    • Pustules joining and becoming confluent

Variola Major

  • Center for Food Security and Public Health Iowa State University - 2004

Variola Major

  • Center for Food Security and Public Health Iowa State University - 2004
  • Hemorrhagic
    • Less than 3% of all cases
    • 2 types, early and late
    • Death occurs before pox lesions appear

Variola Minor

  • Center for Food Security and Public Health Iowa State University - 2004

Differentiating Diseases

  • Center for Food Security and Public Health Iowa State University - 2004
  • FEVER
  • RASH Appearance
  • Development
  • Distribution
  • On palms & soles
  • DEATH
  • SMALLPOX
  • CHICKENPOX
  • At time of rash
  • 2–4 days before the rash
  • Pocks at same stage
  • Rapid
  • Slow
  • More pocks on body
  • More pocks on arms & legs
  • Usually absent
  • Usually present
  • Very uncommon
  • More than 10%

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