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[Encyclopedia of Differential Diagnosis in Dermatology] Paul Schneiderman, Marc E. Grossman - A Clinician\'s Guide to Dermatologic Differential Diagnosis, Volume 1 The Text (Encyclopedia of Differential Diagnosis in D

CONGENITAL LESIONS
Aplasia cutis congenita with epidermolysis bullosa
DEGENERATIVE
Neuropathic ulcer (trophic ulcer) 
Charcot–Marie–Tooth syndrome with neurotrophic foot ulcer
Decubitus
Diabetes
Hereditary sensory neuropathy 
Clin Exp Derm 1:91–92, 1976
Leprosy
Neuropathy
Paraplegias
Syringomyelia – trophic ulcer 
Rook p.2265, 1998,
Sixth Edition
Tabes dorsalis
Trigeminal trophic syndrome 
J Dermatol 18:613–615, 1991
DRUG-INDUCED
Corticosteroid induced leg ulcers – systemic, intralesional,
topical 
Rook p.2266, 1998, Sixth Edition; AD 92:52–53, 1965
Coumarin necrosis 
AD 122:1408, 1412, 1986
Ergot 
Ghatan p.74, 2002, Second Edition
Granulocyte-colony stimulating factor 
BJD 148:388–401, 2003
Halogens 
Ghatan p.74, 2002, Second Edition
Heparin necrosis
Hydroxyurea – ulcers of the lower legs and feet; often over
lateral malleoli; atrophic, scaling, poikilodermatous patches with
erosions on the backs of the hands, sides of the feet 
JAAD
45:321–322, 2001; AD 137:467–470, 2001; Leuk Lymphoma
35:109–118, 1999; AD 135:818–820, 1999; JAAD 39:372–374,
1998; JAAD 36:178–182, 1997; Cutis 52:217–219, 1993
Levophed ischemic necrosis
Methotrexate 
BJD 148:388–401, 2003
Pentazocine abuse
Vasculitis, drug-induced – furosemide, captopril
EXOGENOUS AGENTS
Contact dermatitis, irritant
Halogenoderma 
BJD 148:388–401, 2003
Silicone injection 
Rook p.2422, 1998, Sixth Edition
Tibial cement extrusion 
J Arthroplasty 13:826–829, 1998
INFECTIONS AND INFESTATIONS
Acanthamebiasis in AIDS 
AD 131:1291–1296, 1995
Actinomycosis
Aeromonas hydrophila
ULCERS, LEG
661
Schneiderman page 600-722.qxd 5/16/2006 6:51 PM Page 661


Alternariosis 
Clin Inf Dis 32:1178–1187, 2001
Amebiasis 
Bolognia p.1301, 2003
Animal bites
Anthrax 
BJD 148:388–401, 2003
Arcanobacterium haemolyticum J Clin Inf Dis 18:835–836, 1994
Aspergillosis, primary cutaneous 
JAAD 31:344–347, 1994;
resembling pyoderma gangrenosum 
JAAD 29:656–658, 1993
Bacillary angiomatosis 
AD 131:963–964, 1995
Bacillus cereus JAAD 47:324–325, 2002
Bacterial endocarditis 
BJD 148:388–401, 2003
BCG vaccination 
BJD 148:388–401, 2003
Bipolaris spicifera AD 125:1383–1386, 1989
Botryomycosis
Brucellosis 
Rook p.2267, 1998, Sixth Edition
Candida albicans – granulomatous panniculitis
JAAD 28:315–317, 1993; J Cut Pathol 16:183–193, 1989
Cat scratch disease 
Rook p.2267, 1998, Sixth Edition
Chromomycosis – feet, legs, arms, face, and neck
AD 113:1027–1032, 1997; BJD 96:454–458, 1977;
AD 104:476–485, 1971
Clostridial gas gangrene – acute ulcer 
BJD 148:388–401, 2003;
Rook p.2265, 1998, Sixth Edition
Coccidioidomycosis 
BJD 148:388–401, 2003
Corynebacterium pyogenes Int J Dermatol 21:407–409, 1987;
epidemic leg ulcers of children in Thailand 
Southeast Asian
J Trop Med Public Health 13:568–574, 1982
Corynebacterium ulcerans – medial and lateral lower leg ulcers
mimicking cutaneous diphtheria with gray membrane and sweet
smell 
Clin Inf Dis 33:1598–600, 2001
Cryptococcosis 
JAAD 5:32–36, 1981
Cytomegalovirus 
Tyring p.187, 2002
Desert sore (Veldt sore) – acute leg ulcer 
Rook p.2265, 1998,
Sixth Edition
Diphtheria (
Corynebacterium diphtheriae) – in drug users Clin
Inf Dis 18:94–96, 1994; cutaneous diphtheria BJD
148:388–401, 2003
Dracunculosis – bulla which ruptures leaving an ulcer 
J Clin Inf
Dis 25:749, 1997
Ecthyma 
Tyring p.322, 2002; Rook p.1158, 1998, Sixth Edition
Ecthyma gangrenosum – 
Pseudomonas, Escherichia coli,
Aeromonas hydrophila BJD 148:388–401, 2003
Epstein–Barr virus (infectious mononucleosis) – cold urticaria
with cold agglutinins and leg ulcers 
Acta DV 61:451–452, 1981
Erysipelas 
BJD 148:388–401, 2003
Eumycetoma
Filariasis – secondary lymphedema
Furuncle
Fusarium, localized JAAD 47:659–666, 2002
Glanders 
Rook p.2267, 1998, Sixth Edition
Granulomatous panniculitis
Actinomyces
Atypical mycobacteria – 
Mycobacterium chelonei
AD 129:1189–1194, 1993
Nocardia
Herpes simplex, chronic in AIDS 
BJD 148:388–401, 2003
Histoplasmosis 
BJD 148:388–401, 2003
Hyalohyphomycosis – 
Acremonium species BJD 150:789–790,
2004
Insect bites 
BJD 148:388–401, 2003
Leishmaniasis 
BJD 151:1165–1171, 2004; Rook p.1413, 1998,
Sixth Edition; Trans R Soc Trop Med Hyg 81:606, 1987; Cutis
38:198–199, 1986
Leprosy – lepromatous leprosy with ulcerated nodules of the
legs and feet 
Rook p.1225, 1998, Sixth Edition; Lucio’s
phenomenon 
JAAD 48:958–961, 2003; AD 135:983–988, 1999
Lyme borreliosis (
Borrelia burgdorferi) – acrodermatitis chronica
atrophicans – red to blue nodules or plaques; sclerosis of lower
legs with ulceration 
BJD 121:263–269, 1989; Int J Derm
18:595–601, 1979
Meleney’s synergistic gangrene 
Rook p.2266, 1998,
Sixth Edition
Melioidosis – pretibial ulcerative vegetative plaque 
Cutis
72:310–312, 2003
Meningococcemia 
BJD 148:388–401, 2003
Mosquito bite hypersensitivity syndrome in Epstein–Barr
virus-associated natural killer cell leukemia/lymphoma – clear
or hemorrhagic bullae with necrosis, ulceration and
scar formation 
JAAD 45:569–578, 2001
Mucormycosis resembling pyoderma gangrenosum
JAAD 29:462–465, 1993
Mycetoma 
BJD 148:388–401, 2003
Mycobacterium abscessus BJD 152:727–734, 2005
Mycobacterium avium complex – traumatic inoculation leg
ulcers, ulcerated nodules, panniculitis, folliculitis, or papules
BJD 130:785–790, 1994; JAAD 19:492–495, 1988
Mycobacterium chelonei Am Rev Resp Dis 119:107–159, 1979
Mycobacterium fortuitum
Mycobacterium haemophilum – ulcerated plaque Ann Intern
Med 120:118–125, 1994
Mycobacterium intracellulare
Mycobacterium kansasii
Mycobacterium marinum
Mycobacterium scrofulaceum
Mycobacterium szulgai
Mycobacterium tuberculosis – scrofuloderma, erythema
induratum, lupus vulgaris, erythema induratum 
JAAD
14:738–742, 1986; tuberculous chancre Clin Dermatol
8 (3/4):49–65, 1990; papulonecrotic tuberculid BJD
148:388–401, 2003
Mycobacteria ulcerans (Buruli ulcer) NEJM 348:1065–1066,
2003; Trans R Soc Trop Med Hyg 94:277–279, 2000; Med Trop
(
Mars) 57:83–90, 1997 (French); Clin Inf Dis 21:1186–1192,
1995; Med Trop (Mars) 55:363–373, 1995; Aust J Dermatol
26:67–73, 1985; Pathology 17:594–600, 1985
Necrotizing fasciitis 
BJD 148:388–401, 2003
Nocardia
North American blastomycosis – ulcers of the leg and foot
Osteomyelitis 
J Derm Surg Oncol 10:384–388, 1984; chronic
ulcer of the heel with underlying osteomyelitis
Pasteurella multocida (also P. haemolytica, P. pneumotropica
and 
P. ureae) – cellulitis with ulceration with hemorrhagic
purulent discharge with sinus tracts 
Medicine 63:133–144, 1984
Phaegedenic ulcer 
BJD 148:388–401, 2003
Phaeohyphomycosis – Curvularia pallescens 
JAAD
32:375–378, 1995
Pinta 
Ghatan p.74, 2002, Second Edition
Protothecosis 
AD 136:1263–1268, 2000
Pseudomonas aeruginosa
Pyoderma 
BJD 148:388–401, 2003
Pyomyositis 
Tyring p.322, 2002

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