INTESTINAL MICROFLORA OF NEWBORN NEONATES OF NEWBORNS DEPENDING ON THE FEEDING
Seitkhanova B.T., Shapambayev N.Z., Omarova G.S., Kurmanbekova Sh.Zh., Doltayeva B.Z., Shapambayeva A.N.
South Kazakhstan Medical Academy "AO", Kazakhstan. Shymkent
Formation and functional development of the gastrointestinal ecosystem of the newborn begins with the moment of
birth and dynamically changes with the age of the person. In the first hours and days the intestine of a newborn is inhabited by
micrococci, staphylococci, enterococci, clostridia., then enter the E. coli, lacto- and bifidobacteria. A large influence on the
function of the gastrointestinal tract of newborns is associated with the course of pregnancy, childbirth and the early neonatal
period, the nature of nutrition, various diseases and many medications. Objective. To study the intestinal microflora of newborn
infants aged 3 to 8 days. By age, during the neonatal period and depending on nutrition, all interviewed children were divided
into 2 groups. Group 1 includes newborns aged 3 to 8 days who were immediately attached to the breast (natural food). 2
groups are children aged from 3 to 5 days, who for various reasons were fed with expressed breast milk. All mothers of the
examined children had a pathological course of pregnancy (toxicosis, gestosis, the threat of interruption in the early and late
periods, anemia, infections - SARS, gardnerelez, ureaplasmosis, water shortage). Prematurely, 14 (12.5%) children were born
(32-36 weeks of gestation), 83 (74.1%) children independently, and 15 (13.4%) children in rapid delivery (caesarean section).
The study of the intestinal microflora in children included sowing on selective nutrient media and the isolation of pure cultures
of 32 species of microorganisms with further determination of their microbiological properties. Results and discussion. All the
children studied showed signs of decompensated dysbiosis, manifested with regurgitation after each feeding, bloating, flatu-
lence, intestinal colic, unstable fast stool with inclusions of undigested lumps, mucus. In the dynamics of breastfeeding in group
1, the regression became less common, mucus in the stool decreased, the consistency condensed, intestinal colic was rarely
observed. All the children interviewed had a positive body mass index. In the comparative analysis in the qualitative and quan-
titative composition of the intestinal microflora, in both groups of children, some differences were found. In children in the second
group, the incidence of bifidobacteria was only 50%, which was significantly lower (p <0.05) than in children of the 1
st
group
(80%). Quantitatively no significant differences were observed. The incidence and number of lactobacilli in children of groups
1 and 2 did not differ significantly (56.9% and 48.5%, respectively) and were significantly lower than normal. In dynamics (on
the 8th day), a significant (p <0.05) increase in the incidence of bifidobacteria in children of the 2
nd
group was observed from
80% to 100%. In addition, the children of both experimental groups showed a significant increase in the quantitative level of
bifidobacteria. The frequency of detection of lactobacilli in children in the dynamics significantly increased and was in both
groups 94.6% and 87.3%, respectively. The quantitative and qualitative level of other groups of obligate-anaerobic bacteria did
not undergo statistically significant changes in dynamics. Conclusion. Thus, as a result of studies it was shown that breast milk
effectively restores the optimal qualitative and quantitative indices of bacterial flora, primarily bifido- and lactobacilli in newborns.
Do'stlaringiz bilan baham: |