Immune System



Download 5,05 Mb.
bet7/10
Sana01.06.2022
Hajmi5,05 Mb.
#628191
1   2   3   4   5   6   7   8   9   10
Bog'liq
Immun Reaktivlik

Primary immune response

  • When the antigenic exposure occurs for the first time, the following events take place-
    • Latent or lag period - Active immunity develops which corresponds to the time required for the host’s immune apparatus to become active.
    • Effector cells-Majority of activated T and B cells against the antigenic stimulus become effector T and B cells

Primary immune response

    • Memory cells- A minor proportion of stimulated T and B cells become memory cells, which are the key cells for secondary immune response.
    • Antibody surge
      • Activated B cells produce antibodies (mainly IgM type).
      • Antibodies appear in the serum in slow & sluggish manner; reach peak, maintain the level for a while and then fall down.
      • Finally, a low titer of baseline antibodies may be maintained in the serum.

Secondary immune response

  • When the same antigenic exposure occurs subsequently, the events which take place are as follows:
    • Latent period
    • Negative phase
    • Antibody surge

BRIDGES BETWEEN INNATE AND ACQUIRED IMMUNITY

  • Macrophages and dendritic cells:
    • Belong to innate immune system but as antigen presenting cells, they present the antigenic peptides to T cells.
    • Cytokines secreted from macrophages (interleukin-1) are also involved in T cell activation.
  • ADCC (antibody dependent cell mediated cytotoxicity):
    • Type of cell mediated immune response (CMI), which involves both innate and adaptive components.
    • Cells of innate immunity such as NK cell, eosinophils, and neutrophils destroy (by cytotoxic effect) the target cells coated with specific antibodies.

Download 5,05 Mb.

Do'stlaringiz bilan baham:
1   2   3   4   5   6   7   8   9   10




Ma'lumotlar bazasi mualliflik huquqi bilan himoyalangan ©hozir.org 2024
ma'muriyatiga murojaat qiling

kiriting | ro'yxatdan o'tish
    Bosh sahifa
юртда тантана
Боғда битган
Бугун юртда
Эшитганлар жилманглар
Эшитмадим деманглар
битган бодомлар
Yangiariq tumani
qitish marakazi
Raqamli texnologiyalar
ilishida muhokamadan
tasdiqqa tavsiya
tavsiya etilgan
iqtisodiyot kafedrasi
steiermarkischen landesregierung
asarlaringizni yuboring
o'zingizning asarlaringizni
Iltimos faqat
faqat o'zingizning
steierm rkischen
landesregierung fachabteilung
rkischen landesregierung
hamshira loyihasi
loyihasi mavsum
faolyatining oqibatlari
asosiy adabiyotlar
fakulteti ahborot
ahborot havfsizligi
havfsizligi kafedrasi
fanidan bo’yicha
fakulteti iqtisodiyot
boshqaruv fakulteti
chiqarishda boshqaruv
ishlab chiqarishda
iqtisodiyot fakultet
multiservis tarmoqlari
fanidan asosiy
Uzbek fanidan
mavzulari potok
asosidagi multiservis
'aliyyil a'ziym
billahil 'aliyyil
illaa billahil
quvvata illaa
falah' deganida
Kompyuter savodxonligi
bo’yicha mustaqil
'alal falah'
Hayya 'alal
'alas soloh
Hayya 'alas
mavsum boyicha


yuklab olish