Children infectious diseases



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  • *anti HCV IgМ, viral RNA

  • anti HЕV IgМ, viral RNA

  • anti HВV IgМ and HВV IgG

  • HBsAg, HbeAg, HbcAg, anti НВс IgM, IgG




    1. Name the clinical criteria of the congenital hepatitis B:

        1. Presence of prodromal period, unexpressed jaundice, expressed cytolysis syndrome

        2. jaundice increases quickly, catarrhal, dyspepsia syndrome,

        3. jaundice is insignificant, satisfactory state, spleen is not enlarged, quick recovery

        4. *jaundice from the first days of life, hepatosplenomegaly, hemorrhagic syndrome, malaise, severe disease

        5. hepatosplenomegaly, delay of intrauterine development




    1. Name the diagnostic criteria of hepatitis B incubation period:

        1. *High activity of hepatic-cellular enzymes, absence of clinical signs, presence of viral antigens in a blood

        2. toxic, dyspepsia, catarrhal, astheno-vegetative syndromes

        3. hepatomegaly, pain syndrome, high activity of hepatic-cellular enzymes

        4. bilirubinuria, urobilinuria, discoloration of excrements

        5. Maximal activity of hepatic-cellular enzymes, absence of clinical signs, presence of viral antigens in a blood




    1. Name the diagnostic criteria of hepatitis B prejaundice period:

        1. Maximal activity of hepatic-cellular enzymes, absence of clinical signs, presence of viral antigens in a blood

        2. High activity of hepatic-cellular enzymes, absence of clinical signs, presence of viral antigens in a blood

        3. *toxic, dyspepsia, catarrhal, astheno-vegetative syndromes, hepatomegaly, pain syndrome, high activity of hepatic-cellular enzymes, presence of viral antigens in a blood

        4. Rashes on a skin, hemorrhagic syndrome, splenomegaly, maximal activity of hepatic-cellular enzymes

        5. hepatomegaly, pain syndrome, maximal activity of hepatic-cellular enzymes, bilirubinuria, urobilinuria, discoloration of excrements




    1. Name the laboratory criteria of hepatitis B moderate degree:

        1. *bilirubin up to 85 mcmol/l (indirect is up to 25 mcmol/l) , aminotranspherase level 5-10 times more than norm, prothrombin index 70-80 %, normal sulemic test

        2. bilirubin up to 85 mcmol/l (indirect is up to 25 mcmol/l), aminotranspherase level 5-10 times more than norm, prothrombin index 70-80 %

        3. bilirubin up to 85 mcmol/l (indirect is up to 25 mcmol/l), aminotranspherase level 5-10 times more than norm, prothrombin index 70-80 %, sulemic test is considerably reduced

        4. bilirubin is over 200 mcmol/l (indirect is over 50 mcmol/l), aminotranspherase level 15-30 times more than norm, prothrombin index less than 60 %, sulemic test is normal

        5. bilirubin 85-200 mcmol/l (indirect is up to 50 mcmol/l), aminotranspherase level 10-15 times more than norm, prothrombin index 60-70 %, sulemic test is considerably reduced




    1. Name the laboratory criteria of hepatitis С mild severity:

        1. bilirubin 85-200 mcmol/l (indirect is up to 50 mcmol/l), aminotranspherase level 10-15 times more than norm, prothrombin index 60-70 %

        2. *bilirubin up to 85 mcmol/l (indirect is up to 25 mcmol/l), aminotranspherase level 5-10 times more than norm, prothrombin index 70-80 %

        3. bilirubin up to 85 mcmol/l (indirect is up to 25 mcmol/l), aminotranspherase level 5-10 times more than norm, prothrombin index 70-80 %, sulemic test is considerably reduced

        4. bilirubin is over 200 mcmol/l (indirect is over 50 mcmol/l), aminotranspherase level 15-30 times more than norm, prothrombin index less than 60 %, sulemic test is normal

        5. bilirubin 85-200 mcmol/l (indirect is up to 50 mcmol/l), aminotranspherase level 10-15 times more than norm, prothrombin index 60-70 %, sulemic test is considerably reduced




    1. Name the laboratory criteria of severe hepatitis B:

        1. bilirubin up to 85 mcmol/l (indirect is up to 25 mcmol/l), aminotranspherase level 5-10 times more than norm, prothrombin index 70-80 %, normal sulemic test

        2. bilirubin up to 85 mcmol/l (indirect is up to 25 mcmol/l), aminotranspherase level 5-10 times more than norm, prothrombin index 70-80 %, sulemic test is considerably reduced

        3. bilirubin 85-200 mcmol/l (indirect is up to 50 mcmol/l), aminotranspherase level 10-15 times more than norm, prothrombin index 60-70 %, sulemic test is considerably reduced

        4. bilirubin is over 200 mcmol/l (indirect is over 50 mcmol/l), aminotranspherase level 15-30 times more than norm, prothrombin index less than 60 %, sulemic test is normal

        5. *bilirubin is over 200 mcmol/l (indirect is over 50 mcmol/l), aminotranspherase level 15-30 times more than norm, prothrombin index less than 60 %, sulemic test is considerably reduced




    1. Name the terms of hepatitis B active prophylaxis according the Ukrainian vaccination schedule.

        1. First 12 hours of life, 1, 3, 5 months

        2. *First 12 hours of life, 1, 6 months

        3. First 12 hours of life, 1, 6, 12 months

        4. 3-5 days, 7, 14 years

        5. 3, 4, 5 months, revaccination in 18 months




    1. Name the ways of hepatitis B virus transmission.

        1. parenteral, transmissive, domestic

        2. Food, water, domestic, sexual

        3. *parenteral, vertical, sexual, domestic

        4. parenteral, transplacental, domestic

        5. parenteral, transplacental, transmissive




    1. Name the ways of hepatitis C virus transmission.

        1. Food, water, domestic, sexual

        2. parenteral, transmissive, domestic

        3. parenteral, transplacental, domestic

        4. *parenteral, vertical, sexual, domestic

        5. parenteral, transplacental, transmissive




    1. The immunity against Rotaviruses is mainly conditioned by:

        1. Ig M and Ig G

        2. *Ig A and interferon

        3. Ig G and interferon

        4. Ig E and interferon

        5. Ig D and Ig G




    1. The main value in acute intestinal infection verifying has:

        1. complete blood test

        2. coprological method

        3. serological test

        4. blood culture

        5. *fecal culture




    1. The deficit of body weight in 3rd degree malnutrition is:

        1. Up to 5%

        2. 5-10%

        3. 11-20%

        4. 21-30%

        5. *Over 30%




    1. The deficit of body weight in malnutrition of 1st degree is:

        1. Up to 5%

        2. 5-10%

        3. *11-20%

        4. 21-30%

        5. Over 30%




    1. The diagnosis of chronic hepatitis С is established if the disease's duration is:

        1. More than 2 months

        2. More than 3 months

        3. More than 4 months

        4. More than 5 months

        5. *More than 6 months




    1. The malnutrition degree in infant can be measured by the thickness of skin fold:

        1. *at umbilical level

        2. subscapularly

        3. on the inner surface of the thigh

        4. on the outer surface of the thigh

        5. on the outer surface of the shoulder




    1. The what is typical for the unicteric form of viral hepatitis A?

        1. absence of changes of excrements, urine, bilirubin level

        2. Level of aminotranspherase is normal, increase of bilirubin level

        3. *the increase of aminotranspherase activity, absence of jaundice

        4. jaundice, increase of enzymes activity

        5. There is no right answer




    1. The pre-jaundice period of viral hepatitis A is characterized by the increase of:

        1. Indirect bilirubin, tymol test

        2. Cholesterol, ALAT

        3. tymol test, alkaline phosphatase

        4. cholesterol, beta-lipoproteins, indirect bilirubin

        5. *ALAT, ASAT, direct bilirubin




    1. Name the source of dysentery infection.

        1. Patients with dysentery;

        2. Patients and carriers;

        3. *Carriers;

        4. Small rodents.

        5. Insects.




    1. When does it follow to expect clinical signs of disease at contacts in the focus of shigellosis (latent period course)?

        1. Through 1-2 hours.

        2. From 1 to 2 days.

        3. *From 1 to 7 days.

        4. Till 1 month.

        5. From 1 to 3 months.




    1. The source of infection at viral hepatitis A is:

        1. patient and animal

        2. *ill person

        3. man, carrier and patient

        4. animal and carrier

        5. insects




    1. The subclinical viral hepatitis A form is characterized by:

        1. Insignificant jaundice of skin, the base phosphatase increased

        2. subfebrile temperature, dark urine, colorless excrements

        3. Brief jaundice, increase of tymol test

        4. hemorrhagic syndrome

        5. *clinical displays are absent, ALAT, ASAT are raised




    1. The thickness of skin fold at the navel is 0,2 cm, that is typical for:

        1. *3rd degree malnutrition

        2. 2nd degree malnutrition

        3. 1st degree malnutrition

        4. eutrophya

        5. paratrophya




    1. The thickness of skin fold at the navel is 0,6 cm, that is typical for:

        1. 3rd degree malnutrition

        2. *2nd degree malnutrition

        3. 1st degree malnutrition

        4. eutrophya

        5. paratrophya




    1. The thickness of skin fold at the navel is 1 cm, that is typical for:

        1. 3rd degree malnutrition

        2. 2nd degree malnutrition

        3. *1st degree malnutrition

        4. eutrophya

        5. paratrophya




    1. At the children of what age group dysentery occurs more frequent?

        1. 0-12 months

        2. 1-2 years

        3. *2-7 years

        4. 7-10 years

        5. 10-14 years




    1. What from the enumerated serological tests should be done to reveal antibodies to typhoid fever?

        1. brake of hemagglutination

        2. precipitation

        3. complement binding

        4. *passive hemagglutination

        5. agglutination




    1. To what family does Escherichia belong?

        1. Micrococcaceae

        2. *Enterobacteriaceae

        3. Neisseriaceae

        4. Vibrionaceae

        5. Korynebacteriaceae




    1. Variants of prodromal period at viral hepatitis A:

        1. Convulsive, dyspepsia

        2. *Dyspepsia, astenic, catarrhal

        3. Catarrhal, hemorrhagic

        4. hepatolienal, convulsive

        5. There is no right answer




    1. Virus of hepatitis A in the human organism is contained in:

        1. Feces

        2. Blood and urine

        3. Blood and bile

        4. Tears and saliva

        5. *Blood, feces, urine




    1. Way of viral hepatitis A transmission is:

        1. Contact-domestic

        2. air-droplet

        3. *fecal-oral

        4. All answers are correct

        5. There is no right answer




    1. What antigens does the E. coli have?

        1. *O-, K- and H-antigens.

        2. O-, Vi-antigens.

        3. O-, H-antigens.

        4. O-, K-antigens.

        5. O-antigens.




    1. What is the average duration of hepatitis B incubation period?

        1. 3-6 weeks

        2. 2-3 months

        3. 6-26 weeks

        4. *13-16 weeks

        5. 20-22 weeks




    1. What is the average duration of hepatitis C incubation period?

        1. 3-6 weeks

        2. 2-3 months

        3. 6-26 weeks

        4. 13-16 weeks

        5. *20-22 weeks




    1. What is basis therapy at viral hepatitis A?

        1. *Regime and diet

        2. Regime and enterosorption

        3. glucocorticoids

        4. detoxication therapy

        5. vitamin therapy




    1. What conditions are unfavorable for choleric vibrio:

        1. Drying

        2. Heat

        3. *Disinfectants

        4. Soil water

        5. Stay in the soil




    1. What diet is appointed at viral hepatitis A?

        1. 3

        2. *5-5а

        3. 9

        4. 10

        5. 15




    1. What disease severity is characteristic for hepatitis С in an acute period?

        1. *mild, asymptomatic

        2. moderate

        3. moderate, severe

        4. severe, fulminant

        5. fulminant




    1. What diseases does it follow to differentiate the congenital hepatitis С with?

          1. Hepatitis A, Е, biliary dyskinesia

        1. *sepsis, biliary atresia, TORCH-infections, massive hemorrhages

        2. sepsis, pseudotuberculosis, infectious mononucleosis

        3. Gilbert syndrome, leptospirosis, hemolytic anemia

        4. hemolytic disease of new-born, hepatitis Delta, cholecystitis.




    1. What does the character of hepatitis B duration depend on?

        1. From mechanism and way of virus transmission

        2. From character of genetically definite immune answer

        3. *From a dose and infectiousness of virus, character of the organism immune answer

        4. From duration of latent period

        5. From duration of prejaundice period




    1. What dose of prednisone is appointed to the infants with unfavorable premorbid background in case of viral hepatitis A?

        1. *2-3 mg/kg

        2. 4-5 mg/kg

        3. 5-10 mg/kg

        4. 0.5-1 mg/kg

        5. 1-2 mg/kg




    1. What is the duration of patient's dispensarization in case of severe hepatitis B?

        1. 6 months with examination and laboratory investigation in 7 days, 1, 3, 6 months

        2. 9 months with examination and laboratory investigation in1, 3, 6, 9 months

        3. *12 months with examination and laboratory investigation in 1, 3, 6, 9, 12 months

        4. 2 years with examination and laboratory investigation in 1, 3, 6, 9, 12, 18, 24 months

        5. 3 years with examination and laboratory investigation in 1, 3, 6, 9, 12, 18, 24, 36 months




    1. What is the duration of severe hepatitis B base therapy?

        1. 10 days

        2. 14 days

        3. 21 day

        4. *30 days

        5. 45 days




    1. What is the duration of the bed regime at moderate hepatitis B?

        1. *1 week

        2. 2 weeks

        3. 3 weeks

        4. 4 weeks

        5. 6 weeks




    1. What features of acute dysentery are typical for infants?

        1. Continuously relapsed course.

        2. Absence of inflammation signs at sigmoscopy.

        3. Watery stools.

        4. Repeated vomits.

        5. *Metheorysm and absence of tenesms.




    1. What from the pointed representatives of the E.coli usually cause the disease in infants?

        1. E.coli, that belong to normal microbiocynosis of intestine

        2. *enteropathogenic E.coli

        3. enteroaggregative E.coli

        4. enteroinvasive E.coli

        5. enterohemolytic E.coli




    1. What hepatitis С typical consequences do you know?

        1. liver fibrosis, chronic hepatitis

        2. recovery with complete renewal of liver structure and function

        3. damage of biliary system and liver

        4. recovery with a defect (remaining fibrosis)

        5. *Chronic hepatitis, liver cirrhosis, hepatocellular carcinoma




    1. What seasonality is typical for viral hepatitis A?

        1. spring-summer

        2. *summer-autumn

        3. winter-spring

        4. autumn-winter

        5. seasonality is not typical




    1. What features are typical for the hepatitis B virus?

        1. *DNA-containing virus from hepadnavirus family, 42-52 nm;

        2. RNA-containing virus from enterovirus family, 27-30 nm;

        3. Virus from flavivirus family, 22-60 nm;

        4. virus 35-37 nm with small RNA and shell of the HB virus;

        5. virus-like particle of spherical form, 27 nm.




    1. What specific method of diagnostics is needed to prove viral hepatitis A?

        1. *presence of anti HAV ІgM and anti HAV IgG in the blood

        2. Increase of aminotranspherase level

        3. Increase of bilious pigments in the urine

        4. Increase of tymol test

        5. hyperbilirubinemia




    1. What treatment is appointed at the moderate form of viral hepatitis A?

        1. Base therapy

        2. *Base therapy, detoxication therapy

        3. diet + enterosorption

        4. glucocorticoids

        5. hepatoprotectors




    1. What is the volume of desiccation therapy at the moderate form of viral hepatitis A?

        1. *40-50 ml/kg per day

        2. 50-100 ml/kg per day

        3. 150-200 ml/kg per day

        4. 200-300 ml/kg per day

        5. 300-350 ml/kg per day




    1. What is the volume of detoxication therapy at the severe form of viral hepatitis A?

        1. *50-100 ml/kg per day

        2. 150-200 ml/kg per day

        3. 200-300 ml/kg per day

        4. All answers are correct

        5. A right answer is not present




    1. When does it follow to give choleretics at hepatitis B, moderate degree?

        1. From the 1st day of jaundice period

        2. From the 2nd week of jaundice period

        3. *From the 3rd week of jaundice period

        4. From the 4th week of jaundice period

        5. Does not need to give




    1. Which state is the most convenient to measure malnutrition in infant?

        1. Trophic Index

        2. Mass-growth coefficient

        3. The thickness of skin folds at the navel level

        4. *Lack of body weight (%)

        5. The distribution of subcutaneous fat in body areas




    1. Who is the source of the hepatitis B infection?

        1. patients with acute and chronic forms of disease

        2. transmitters of superficial antigen

        3. patients with acute and chronic forms, healthy transmitters of core antigen

        4. *patients with acute and chronic forms, healthy transmitters of superficial antigen

        5. patients with acute and chronic forms, healthy transmitters of infectiousness antigen




    1. Who is the source of the hepatitis С infection?

        1. patients with acute and chronic forms of disease

        2. transmitters of superficial antigen

        3. *carriers, patients with acute and chronic forms

        4. patients with acute and chronic forms, healthy transmitters of core antigen

        5. patients with acute and chronic forms, healthy transmitters of infectiousness antigen




    1. With appearance of jaundice at patients with viral hepatitis A:

        1. their condition worsened

        2. *their condition becomes better

        3. the sizes of liver diminish

        4. the temperature of body rises

        5. hemorrhagic rash appears




    1. Indicate age, when revaccination against tuberculosis is made:

        1. 1 year

        2. 2 years

        3. *7 years

        4. 11 years

        5. 18 years




    1. Indicate age, when revaccination against tuberculosis is made:

        1. 1 year

        2. 2 years

        3. 6 years

        4. 11 years

        5. *14 years


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