Bachelor degree



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Module designation


Modules of Individual educational direction /traectory (IED)

Biotechnology of Antiinfection Solutions Acquiring



Module level, if applicable


IED 1: «Biotechnology of micro-organisms»


Code, if applicable


BASA 3305


Subtitle, if applicable


-

Courses, if applicable


Course

Credits

Biotechnology of Antiinfection Solutions Acquiring


3




2 lectures+1 Lab per week

Semester(s) in which the module is taught


6 semester

Person responsible for the module


Dr., Professor Mukasheva T.D.


Lecturer


Dr., Professor Mukasheva T.D., associate Professor, candidate of Biological Science Ignatova L.V., Мukhataeva K.

Language


Kazakh, Russian, English

Relation to curriculum


(State/Social/ Vocational/IET)

IET


Type of teaching, contact Hours


Lecture

Practicum

Seminars

30 hours per semester

2 hours per week



15 hours per semester

1 hour per week




-




Workload


Lectures

Guided self-study

Self-study

30 hours per semester

2 hours per week



-

60 hours per semester (4 hours per week)

Credit points


3 US credit = 5 ECTS


Requirements according to

the examination regulations


50% of overall scores

Recommended prerequisites


BMB 2414 Basics of Microorganisms Biotechnology

Module objectives/intended

learning outcomes



Knowledge


Skills


Competences


Students at the end of the course should

know: сlassification of anti-infective drugs; technology of anti-infective drugs;
principles of vaccination, chemotherapy, and laboratory diagnosis of infectious diseases.


Must own the:
skills in industrial microbiology laboratories; methods of determining the antimicrobial activity of the preparations;
methods of microbiological control in the workplace.

Be able to: determine the antimicrobial activity of the preparations; carry out microbiological control in the workplace.

Content


Discipline gives an idea about the basic principles, characteristics, methods of biotechnological production and sanitary-microbiological control of anti-infective drugs, especially of microorganisms that are most important for medicine, the principles of vaccination, chemotherapy, and laboratory diagnosis of infectious diseases.

Biotechnology and medicine.

The selection of soil microorganisms as objects for the screening of biologically active compounds. The main methods of isolation of microorganisms

Вiological objects , as a means of production of medical, preventive and diagnostic tools Improvement of biological objects by methods of mutagenesis and selection

Identification and characterization of microorganisms-producers of antibiotics

Improvement of biological objects by methods of cell engineering, genetic engineering

Cultural and morphological evaluation of grown colonies, isolation of pure cultures of microorganisms with the primary antagonistic activity.


The main stages of the biotechnological process. The process of biosynthesis. Classification by technological parameters.

Comparison of morphological characteristics of the main producers at a superficial and deep cultivation.

The problem of finding, creating and antibiotic use in medical practice.

Microbiological methods of determination of antibiotic activity. Preparatory stage.

Mechanisms of biosynthesis of antibiotics. Classification mechanisms. Inhibitors of education of cell walls of bacteria.

The selection of antibiotics from cultural liquid by thin layer chromatography




Study and examination

requirements and forms of

examination

Oral exam, tests

1st interim control: attendance, in-class discussion, problem solving, testing

2nd interim control: attendance, in-class discussion, problem solving, testing

Final examination: written, 2 theoretical questions, 1 practical question



Media employed


Video lectures, Audio books, presentations

Reading list


  1. Gusev M.V., L.A. Mineeva Microbiology. Moscow: Moscow State University Press, 2006. p.5-20. (in russian)

  2. Higgins I, Best D., J..Joyce. 1998. Biotechnology: Principles and applications. P. 485. (in english)

  3. G. Schlegel General Microbiology. Springer-Verlag, 2005

  4. Netrusov A.I., I.B. Kotova General microbiology. Moscow: Publishing Center "Academy", 2007. (in russian)

  5. Shigaeva MH, Chiu WL General microbiology. Almaty. Publ . Kazak university, 2008. 320 Р. (in kazakh)

  6. Katalinski A.V. 2003. Medicinal preparations of directed action: the origins and mechanisms of action. P 228. (in russian)


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