Сборник содержит материалы научной мультиконференции «Биотех- нология медицине будущего»

Russian experience in phage therapy in localized infections
Nina Tikunova, Vera Morozova, Valentin Vlassov 
Institute of chemical biology and fundamental medicine, Siberian branch of Russian academy 
of science, Novosibirsk, Russia
Recent years, an increasing microbial resistance takes place around the world. In Russia, 
more than 35% of nosocomial infections are multidrug-resistant that requires alternative 
preparations and approaches for treatment. One of these may be application of bacteriophages. 
Since 1930-40, bacteriophages have been extensively used for dysentery and typhoid prophy-
laxis and treatment in the former Soviet Union. When bacteriophages against major causative 
agents of suppurative inflammation were identified, they have been also applied in surgical 
practice to treat purulent wounds and post-operative infectious complications. After the 
advent of various antibiotics, the use of bacteriophages in surgery was significantly decreased 
in Russia, but not stopped as antibiotic treatment sometimes failed even with antibiotic-
sensitive bacteria. The emergence of multidrug-resistant bacteria revived the interest in phage 
therapy as a possible alternative to traditional antibiotics. The results of phage therapy and 
complex therapy including phage and antibiotic treatment in clinical practice in Russia will be 
presented. Data on application of bacteriophages against localized infections such as wound 
and postoperative infections, burn infections and infections associated with trophic ulcers, 
including diabetic foot ulcers, will be described.

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Всероссийская мультиконференция с международным участием «Биотехнология – медицине будущего»
29 июня - 2 июля 2019 г., г. Новосибирск, Россия
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Персонализированная фаготерапия как составная часть комплексного