Тошкент врачлар малакасини ошириш институти

The object of the research work are 400 male patients from 18 to 59 year 
old, suffering from alcoholism and drug addiction. 
The subject of the research work personality-biological, social-
psychological, clinical-anamnestic and clinical-psychopathological and clinico-
psychological characteristics of males with dependence on alcohol and opioids
.
Methods of the research work. Statistical, clinical, follow-up study, clini-
cal observation, experimental-psychological and neurovisual methods have been 
used of the research. 
The scientific novelty of the research work is as follows: 
interference of existence of perinatal pathology in the anamnesis, prevailing 
of emotionally unstable and impulsive personality types, hereditary drug abuse in-
clination and mental illnesses major role in the formation of deviant behavior in 
patients with premorbid alcoholism and opiate addiction have been proved; 
high progressive progress of addiction in patients with alcoholism and drug 
addiction with deviant behavior in premorbid, which in turn is associated with fac-
tors such as early onset of drug abuse, the rapid formation of dependence, severe 
course of abstinent syndrome; 
it was established that at most of alcoholics and drug addicts with deviant 
behavior in a premorbid the reference high-progreduated course of dependence ex-
plained by the early beginning of the use drugs, high speed of formation and the 
heavy course of an abstinence syndrome. 
the prevalence of behavioral and affective components of the pathological 
craving in patients with deviant behavior in premorbid has been justified; 
morphological and structural changes in the brain, which vary from slight 
signs of an atrophy to expansion of subcortical space and furrows of bark of frontal 
lobes, as a result of high gradient progress of dependence in patients with deviant 
behavior have been identified; 
the necessity of introducing cognitive-behavioral therapy to improve the so-
cial adaptation of patients with alcoholism and drug addiction with deviant behav-
ior in premorbid has been pathogenetically justified.