N., and Bakry, N. M. (2006)

<04 Article Title>. Journal of Chromatography, A 1028: <25 Page(s)>.

Chemical of Concern: FVL, TCZ; Habitat: <40 Habitat Code>; Effect Codes: <08 Effects Code>.

Sakr, S. A. and Gabr, S. A. (1992). Ultrastructural Changes Induced by Diazinon and Neopybuthrin in Skeletal Muscles of Tilapia nilotica. Bull.Environ.Contam.Toxicol. 48: 467-473.

EcoReference No.: 5008

Chemical of Concern: DZ; Habitat: A; Effect Codes: CEL; Rejection Code: NO ENDPOINT(DZ).

SALES, N., LEVOT GW, and HUGHES PB (1989). MONITORING AND SELECTION OF RESISTANCE TO PYRETHROIDS IN THE AUSTRALIAN SHEEP BLOWFLY LUCILIA-CUPRINA. MED VET ENTOMOL; 3 287-292.

Chem Codes: Chemical of Concern: DZ Rejection Code: SURVEY.

BIOSIS COPYRIGHT: BIOL ABS. RRM DAMALINIA-OVIS PEST CONTROL INSECTICIDE CYPERMETHRIN CYHALOTHRIN CYCLOPROTHRIN DIAZINON CARBAMATE BUTACARB DELTAMETHRIN ORGANOPHOSPHATE DDT Animals/Genetics/ Biochemistry/ Herbicides/ Pest Control/ Pesticides/ Animals/ Arachnida/ Entomology/Economics/ Pest Control/ Arachnida/ Entomology/Economics/ Insecticides/ Pest Control/ Pesticides/ Animal/ Disease/ Insects/Parasitology/ Anoplura/ Diptera/ Artiodactyla

Salman, Michael and Rottem, Shlomo (1995). The cell membrane of Mycoplasma penetrans: lipid composition and phospholipase A1 activity. Biochimica et Biophysica Acta (BBA) - Biomembranes 1235: 369-377.
Chem Codes: Chemical of Concern: DZ Rejection Code: METHODS.

Analysis of Mycoplasma penetrans membrane lipids revealed that, in addition to large amounts of unesterified cholesterol, M. penetrans incorporated exogenous phospholipids, preferentially sphingomyelin, from the growth medium. The major phospholipids synthesized de novo by M. penetrans were phosphatidylglycerol (PG) and diphosphatidylglycerol (DPG). In vivo labeling of PG and DPG by growing the cells with radioactive palmitate or oleate, followed by snake venom phospholipase A2 treatment, enabled us to assess the positional distribution of fatty acids in these lipids. Saturated fatty acids were found preferentially in position 2 of the glycerol backbone, and not in position 1 as found elsewhere in nature, while unsaturated fatty acids prefer position 1. M. penetrans membranes contain phospholipase activity of the A1 type, removing a fatty acid from the sn-1 ester bond of phospholipids. The activity was neither stimulated by Ca2+ nor inhibited by EGTA and had a broad pH spectrum. The substrate specificity of the enzyme was investigated with various natural lipids and with a fluorescent analog of the phosphatidylcholine. The enzyme was equally active toward phosphatidyl-choline and phosphatidylglycerol, but did not hydrolyze diphosphatidylglycerol. The enzyme did not act on triacylglycerol, diacylglycerol or cholesteryl ester, but low activity was detected toward monoacylglycerol. The enzyme was heat-sensitive and detergent-sensitive, and was almost completely inhibited by p-bromophenacylbromide (50 [mu]M), but was not affected by SH reagents. This study is the first one reporting phospholipase A1 activity in Mollicutes. A possible role of this enzyme in forming lipid mediators upon the interaction of M. penetrans cells with eukaryotic cells is suggested. Phospholipase A1/ Membrane lipid/ AIDS/ (Molliicutes)/ (Mycoplasma penetrans)

Salvucci, Michael E. (2004). Potential for interactions between the carboxy- and amino-termini of Rubisco activase subunits. FEBS Letters 560: 205-209.
Chem Codes: Chemical of Concern: DZ Rejection Code: METHODS.

The subunit interactions of Rubisco activase were investigated using mutants containing an introduced Cys near the N- and/or C-terminus. Chemical cross-linking of the C-terminal and double insertion mutant produced subunit dimers and dimers plus high ordered oligomers, respectively. Fluorescence measurements with N,N′-dimethyl-N-(iodoacetyl)-N′-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)ethylenediamine showed that the environment around the introduced Cys near the C-terminus becomes more hydrophilic upon nucleotide binding. The Cys insertion mutants catalyzed Rubisco activation and ATP hydrolysis even when the subunits of the C-terminal or double insertion mutants were completely cross-linked. The results indicate that the termini of adjacent activase subunits are in close proximity and can be modified and even joined without affecting enzyme function. Author Keywords: AAA+ protein/ ATPase/ Carbon metabolism/ Cross-linking/ Photosynthesis

SAMOKYSZYN VM, THOMAS CE, REIF DW, SAITO, M., and AUST SD (1988). RELEASE OF IRON FROM FERRITIN AND ITS ROLE IN OXYGEN RADICAL TOXICITIES. DRUG METAB REV; 19 283-304.
Chem Codes: Chemical of Concern: DZ Rejection Code: METABOLSIM.

BIOSIS COPYRIGHT: BIOL ABS. RRM RAT DIQUAT XENOBIOTIC LIPID PEROXIDATION HEPATOTOXICITY Gases/ Biochemistry/ Amino Acids/ Peptides/ Proteins/ Lipids/ Minerals/ Minerals/Metabolism/ Digestive System Diseases/*Pathology/ Digestive System/Pathology/ Poisoning/ Animals, Laboratory/ Muridae

Sams, C., Cocker, J., and Lennard, M. S. (2004). Biotransformation of chlorpyrifos and diazinon by human liver microsomes and recombinant human cytochrome P450s (CYP). Xenobiotica [Xenobiotica]. Vol. 34, no. 10, pp. 861-873. Oct 2004.
Chem Codes: Chemical of Concern: DZ Rejection Code: HUMAN HEALTH.

ISSN: 0049-8254

Descriptors: Chlorpyrifos
Descriptors: Diazinon
Descriptors: Liver
Descriptors: Microsomes
Descriptors: biotransformation
Descriptors: Cytochrome P450
Descriptors: Hydrolysis
Descriptors: Insecticides
Descriptors: Detoxification
Abstract: 1. The cytochrome P450 (CYP)-mediated biotransformation of the organophosphorothioate insecticides chlorpyrifos and diazinon was investigated. Rates of desulphuration to the active oxon metabolite (chlorpyrifos-oxon and diazinon-oxon) and dearylation to non-toxic hydrolysis products were determined in human liver microsome preparations from five individual donors and in recombinant CYP enzymes. 2. Chlorpyrifos and diazinon underwent desulphuration in human liver microsome with mean K sub(m) = 30 and 45 mu M and V sub(max) = 353 and 766 pmol min super(-1) mg super(-1), respectively. Dearylation of these compounds by human liver microsome proceeded with K sub(m) = 12 and 28 mu M and V sub(max) = 653 and 1186 pmol min super(-1) mg super(-1), respectively. The apparent intrinsic clearance (V sub(max)/K sub(m)) of dearylation was 4.5- and 2.5-fold greater than desulphuration for chlorpyrifos and diazinon, respectively. 3. Recombinant human CYP2B6 possessed the highest desulphuration activity for chlorpyrifos, whereas CYP2C19 had the highest dearylation activity. In contrast, both desulphuration and dearylation of diazinon were catalysed at similar rates, in the rank order CYP2C19 > CYP1A2 > CYP2B6 > CYP3A4. 4. Both organophosphorothioates were more readily detoxified (dearylation) than bioactivated (desulphuration) in all human liver microsome preparations. However, the role of individual CYP enzymes in these two biotransformation pathways varied according to the structure of the organophosphorothioate, which was reflected in different activation/detoxification ratios for chlorpyrifos and diazinon. Variability in activity of individual CYP enzymes may influence interindividual sensitivity to the toxic effects of chlorpyrifos and diazinon.
DOI: 10.1080/00498250400017273
Language: English
English
Publication Type: Journal Article
Classification: X 24133 Metabolism
Subfile: Toxicology Abstracts

Sams, C., Mason, H. J., and Rawbone, R. (2000). Evidence for the activation of organophosphate pesticides by cytochromes P450 3A4 and 2D6 in human liver microsomes. Toxicology Letters [Toxicol. Lett.]. Vol. 116, no. 3, pp. 217-221. 16 Aug 2000.

Chem Codes: Chemical of Concern: DZ Rejection Code: HUMAN HEALTH.

ISSN: 0378-4274

Descriptors: Pesticides (organophosphorus)
Descriptors: Chlorpyrifos
Descriptors: Parathion
Descriptors: Liver
Descriptors: Microsomes
Abstract: The role of specific cytochrome P450 isoforms in catalysing the oxidative biotransformation of the organophosphorothioate pesticides parathion, chlorpyrifos and diazinon into structures that inhibit cholinesterase has been investigated in human liver microsomes using chemical inhibitors. Pesticides were incubated with human liver microsomes and production of the anticholinergic oxon metabolite was investigated by the inhibition of human serum cholinesterase. Quinidine and ketoconazole at 10 mu mol/l inhibited oxidative biotransformation. Compared to control incubations (no inhibitor) where cholinesterase activity was inhibited to between 1 and 4% of control levels, incorporation of the CYP2D6 inhibitor quinidine into the microsomal incubation resulted in cholinesterase activity of 50% for parathion, 38% for diazinon and 30% for chlorpyrifos. Addition of the CYP3A4 inhibitor ketoconazole to microsomal incubations resulted in 66% cholinesterase activity with diazinon, 20% with parathion and 5% with chlorpyrifos. The unexpected finding that CYP2D6, as well as CYP3A4, catalysed oxidative biotransformation was confirmed for chlorpyrifos and parathion using microsomes prepared from a human lymphoblastoid cell line expressing CYP2D6. While parathion has been investigated only as a model compound, chlorpyrifos and diazinon are both very important, widely used pesticides and CYP2D6 appears to be an important enzyme in their bioactivation pathway. CYP2D6 is polymorphic and hence may influence individual susceptibility to exposure to chlorpyrifos and diazinon as well as other structurally similar pesticides.
DOI: 10.1016/S0378-4274(00)00221-6
Language: English
English
Publication Type: Journal Article
Classification: X 24135 Biochemistry
Subfile: Toxicology Abstracts

Sanchez-Camazano, M., Arienzo, M., Sanchez-Martin, M. J., and Crisanto, T. (1995). Effect of different surfactants on the mobility of selected non-ionic pesticides in soil. Chemosphere 31 : 3793-3801.

Chem Codes: MTL Rejection Code: FATE.

ABSTRACT: BIOSIS COPYRIGHT: BIOL ABS. The influence of the surfactants tetradecyltrimethylammonium bromide (cationic), lauryl sulphate (anionic) and tween 80 (non-ionic) on the leaching of the pesticides diazinon, atrazine, metolachlor and acephate in soil was studied by using soil thin layer chromatography, 14C-labelled pesticides and a linear analyser for measuring the mobility parameter Rf. The results obtained are quite interesting in that they support the use of surfactants for solving soil pollution problems caused by pesticides. The increase or decrease of pesticide mobility in soil was found to depend on the chemical nature of the surfactant, its concentration in the soil or in the leaching water and the pesticide hydrophobicity. Consequently, the surfactant of choice and its concentration will be dictated in each case by the nature of the pesticide involved and the specific problem faced (pesticide immobilization or leaching).

KEYWORDS: Comparative Biochemistry
KEYWORDS: Biochemical Studies-General
KEYWORDS: Biophysics-Molecular Properties and Macromolecules
KEYWORDS: Movement (1971- )
KEYWORDS: Toxicology-Antidotes and Preventative Toxicology (1972- )
KEYWORDS: Toxicology-Environmental and Industrial Toxicology
KEYWORDS: Public Health: Environmental Health-Air
KEYWORDS: Agronomy-Weed Control
KEYWORDS: Pest Control
KEYWORDS: Economic Entomology-Chemical and Physical Control

Sanchez-Camazano M., Iglesias-Jimenez E., and Sanchez-Martin M. J. (1997). City refuse compost and sodium dodecyl sulphate as modifiers of diazinon leaching in soil. Chemosphere 35: 3003-3012.

Chem Codes: Chemical of Concern: DZ Rejection Code: FATE.

The effect of a city refuse compost (CRC) and of an anionic surfactant (sodium dodecyl sulphate (SDS) on the leaching of diazinon (0,0-diethyl 0-2-isopropyl-6-methylpyrimidin-4-yl-phosphorothioate) in the soil was studied using packed soil columns. Breakthrough curves showed the existence of various regimes of pesticide adsorption related to the pesticide and organic material nature and the soil properties. Leaching rate and mass transfer of diazinon decrease following the addition of CRC to the soil and increase after the addition of SDS. The degree of increase or decrease was found to depend strongly on the amendment dose added, especially in the case of SDS. The results afford basic data on which to base the possible use of the organic amendments studied in physicochemical methods designed to prevent the pollution of water by hydrophobic pesticides (immobilization) or to restore soils contaminated by these compounds (leaching).

Sanchez-Camazano, M., Sanchez-Martin, M. J., Poveda, E., and Iglesias-Jimenez, E. (1996). Study of the effect of exogenous organic matter on the mobility of pesticides in soils using soil thin-layer chromatography. Journal of Chromatography A, 754 (1-2) pp. 279-284, 1996.
Chem Codes: Chemical of Concern: DZ Rejection Code: METHODS.

ISSN: 0021-9673

Descriptors: soil
Descriptors: environmental analysis
Descriptors: pesticide mobility
Descriptors: pesticides
Abstract: The effect of soil amendment using urban compost, agricultural organic amendments and surfactants on the mobility of two sparingly-soluble pesticides - diazinon and linuron - was studied by soil thin-layer chromatography. The modifications in R(F) values due to the addition of the amendments were similar for both pesticides. No significant correlation was found between the R(F) values and the content of total organic carbon in the amended soils. This fact indicated that not only the organic carbon content of amended soils but also the amendment nature, specially their content in soluble fractions must play a very important role in the pesticide mobility. The surfactants gave rise to important alterations in pesticide mobility; the pesticides changed from being slightly mobile in natural soil to being immobile in the soil sample modified with tetradecyltrimethylammonium bromide and to being mobile in the soil sample amended with sodium dodecyl sulphate.
Language: English
English
Publication Type: Journal
Publication Type: Article
Country of Publication: Netherlands
Classification: 92.10.1.4 CROP SCIENCE: Crop Physiology: Soil science
Subfile: Plant Science

Sanchez, M. E., Estrada, I. B., Martinez, O., Martin-Villacorta, J., Aller, A., and Moran, A. (2004). Influence of the application of sewage sludge on the degradation of pesticides in the soil. Chemosphere 57: 673-679.

Chem Codes: Chemical of Concern: DZ Rejection Code: FATE.

A study was made of the influence of the application of sewage sludge on the degradation of pesticides in the soil. Two kinds of sludge were used, with different characteristics, one from an urban treatment plant and one from a food processing plant. Three organophosphorus insecticides, fenitrothion, diazinon and dimethoate, were studied. The relative importance was determined of the chemical and biological degradation processes, which involved experiments on soil and sterile soil samples. A comparative study was also made of the degradation of pesticide residues and the evolution of the microbial population. The application of sludge seems to have a complex effect on the degradation of pesticides, determined by the bioavailability and biodegradability of their active ingredient. The biodegradation of pesticide residues brings about alterations in the microorganism population of the soil. Sludge/ Organophosphorus pesticides/ Degradation/ Soil

Sanchez-Martin, M. J., Crisanto, T., Arienzo, M. , and Sanchez-Camazano, M. (1994). Evaluation of the mobility of C14-labelled pesticides in soils by thin layer chromatography using a linear analyser. Journal of Environmental Science and Health Part B Pesticides Food Contaminants and Agricultural Wastes 29 : 473-484.
Chem Codes: MTL Rejection Code: FATE.

ABSTRACT: BIOSIS COPYRIGHT: BIOL ABS. The mobility of seven pesticides in a chromic cambisol soil was studied by soil thin layer chromatography. Pesticide mobilities were determined by means of conventional autoradiographs of the chromatograms, as well as from sequential series of curves and images of the pesticide spots provided by a linear analyser. The Rf values obtained from the autoradiographs and those provided by the linear analyser were quite consistent. Based on such values, pesticide mobility decreased in the following order: acephate > fluometuron > atrazine > ethofumesate > metolachlor > diazinon > glyphosate. According to the mobility scale proposed by Helling and Turner (1968), acephate is highly mobile; atrazine, fluometuron, ethofumesate and metolachlor are moderately mobile; diazinon is slightly mobile; and glyphosate is immobile. The images provided by the linear analyser allow to determine the Rf values for the zones of maximum activity in the pesticide spots (Rfmax), as

KEYWORDS: General Biology-Conservation
KEYWORDS: Radiation-Radiation and Isotope Techniques
KEYWORDS: Ecology
KEYWORDS: Biochemical Studies-General
KEYWORDS: Biophysics-General Biophysical Techniques
KEYWORDS: Toxicology-Environmental and Industrial Toxicology
KEYWORDS: Public Health: Environmental Health-Air
KEYWORDS: Soil Science-Physics and Chemistry (1970- )
KEYWORDS: Pest Control

Sancho, E., Ferrando, M. D., Gamon, M., and Andreu-Moliner, E. (1993). An Approach to the Diazinon Toxicity in the European Eel: Bioaccumulation Studies. Sci.Total Environ.(Suppl.) 461-468.

EcoReference No.: 4352

Chemical of Concern: DZ; Habitat: A; Effect Codes: MOR,ACC; Rejection Code: NO CONTROL(DZ).

Sanders, H. O. and Cope, O. B. (1966). Toxicities of Several Pesticides to Two Species of Cladocerans. Trans.Am.Fish.Soc. 95: 165-169 (Author Communication Used) (Publ in Part As 6797).

EcoReference No.: 888

Chemical of Concern: 24DXY,CBL,DBN,DU,DZ,HCCH,MLN,Naled,CYT,PYN,TFN,RTN,As; Habitat: A; Effect Codes: PHY; Rejection Code: NO CONTROL(ALL CHEMS).

Sands, William A. and Kusel, John R. (1992). Changes in the lateral diffusion of fluorescent lipid analogues in the surface membrane of adult male Schistosoma mansoni. Molecular and Biochemical Parasitology 53: 233-239.

Chem Codes: Chemical of Concern: DZ Rejection Code: NO TOXICANT.

The effect of serotonin on the fluidity of the tegumental membranes of adult male Schistosoma mansoni was assessed by the fluorescence recovery after photobleaching technique. It was demonstrated that the translational diffusion of 5-N′-octadecanoyl aminofluorescein is reduced by a mechanism involving G-protein coupled activation of adenylate cyclase and lowering of intracellular calcium concentration. Furthermore, the lateral diffusion coefficient and the mobile fraction appear to be controlled by calcium and cAMP dependent pathways respectively. No change in the diffusion of the fluorescent phospholipid N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)-phosphatidyl choline was observed, suggesting the two probes used here partition into two different domains that are under independent control. An increase in the amount of protein associating with a membrane cytoskeleton is also demonstrated. Fluidity/ Tegument/ Schistosoma mansoni/ Serotonin

Sangwan, A. K., Chhabra, M. B., and Samantaray, S. (1988). Comparative efficacy of some pesticides against Hyalomma anatolicum anatolicum ticks in vitro. Indian Veterinary Journal [INDIAN VET. J.]. Vol. 65, no. 12, pp. 1084-1087. 1988.
Chem Codes: Chemical of Concern: DZ Rejection Code: IN VITRO.

Descriptors: pesticides

Descriptors: Ixodidae
Descriptors: Hyalomma anatolicum anatolicum
Descriptors: Acari
Abstract: Five commercially available pesticides were assessed in vitro for their comparative toxicity to unfed adults of Hyalomma anatolicum anatolicum . Two of these were also tested against the engorged female ticks. The comparative effectiveness of pesticides was judged in terms of mortality in unfed adults after treatment and reduction of egg laying and hatching in engorged females. Decamethrin 2.8% EC proved the most effective. Of the other agents evaluated, oxinotiofos 50% EC and diazinon 20% EC, fared moderately, while amitraz 12.5% EC was the least effective.
Language: English
English
Publication Type: Journal Article
Classification: Z 05183 Toxicology & resistance
Subfile: Entomology Abstracts

Sapozhnikova, Yelena, Bawardi, Ola, and Schlenk, Daniel (2004). Pesticides and PCBs in sediments and fish from the Salton Sea, California, USA. Chemosphere 55: 797-809.

Chem Codes: Chemical of Concern: DMT Rejection Code: SURVEY.

The Salton Sea, the largest manmade lake in California, is officially designated by the State of California as an agricultural drainage reservoir. The purpose of this study was to determine organochlorine and organophosphorous pesticides, as well as polychlorinated biphenyl (PCB) concentrations in sediments and fish tissues in the Salton Sea and evaluate the relative ecological risk of these compounds. Sediment samples were taken during 2000-2001 and fish tissues (Tilapia mossambique, Cynoscion xanthulu) were collected in May 2001. All samples were analyzed for 12 chlorinated pesticides, 6 organophosphorus pesticides, and 55 polychlorinated biphenyl (PCB) congeners. [sum]Dichlorodiphenyltrichloroethane ([sum]DDT) and total PCB concentrations observed in sediments ranged from 10 to 40 and 116 to 304 ng/g dry wt, respectively. DDT/DDD ratios in sediments and fish tissues of the northern Sea in 2001 indicated recent DDT exposure. Lindane, dieldrin, dichlorodiphenylethane (DDE) and total PCB concentrations detected in sediments exceeded probable effect levels established for freshwater ecosystems, and pp-DDE and total PCB concentrations were higher than effect range-median values developed for marine and estuarine sediments. In fish liver, concentrations of endrin and [sum]DDT exceeded threshold effect level established for invertebrates. [sum]DDT concentrations detected in fish tissues were higher than threshold concentrations for the protection of wildlife consumers of aquatic biota. DDE concentrations in fish muscles tissues were above the 50 ng/g concentration threshold for the protection of predatory birds. Dimethoate, diazinon, malathion, chlorpyrifos, disulfoton varied from [les]0.15 to 9.5 ng/g dry wt in sediments and from [les]0.1 to 80.3 ng/g wet wt in fish tissues. Disulfoton was found in relatively high concentrations (up to 80.3 ng/g) in all organs from Tilapia and Corvina. These results demonstrate continued contamination of specific organochlorine compounds in sediments and resident fish species of the Salton Sea.

Sapozhnikova, Yelena, Bawardi, Ola, and Schlenk, Daniel (2004). Pesticides and PCBs in sediments and fish from the Salton Sea, California, USA. Chemosphere 55: 797-809.
Chem Codes: Chemical of Concern:DMT Rejection Code: 10/SURVEY.

The Salton Sea, the largest manmade lake in California, is officially designated by the State of California as an agricultural drainage reservoir. The purpose of this study was to determine organochlorine and organophosphorous pesticides, as well as polychlorinated biphenyl (PCB) concentrations in sediments and fish tissues in the Salton Sea and evaluate the relative ecological risk of these compounds. Sediment samples were taken during 2000-2001 and fish tissues (Tilapia mossambique, Cynoscion xanthulu) were collected in May 2001. All samples were analyzed for 12 chlorinated pesticides, 6 organophosphorus pesticides, and 55 polychlorinated biphenyl (PCB) congeners. [sum]Dichlorodiphenyltrichloroethane ([sum]DDT) and total PCB concentrations observed in sediments ranged from 10 to 40 and 116 to 304 ng/g dry wt, respectively. DDT/DDD ratios in sediments and fish tissues of the northern Sea in 2001 indicated recent DDT exposure. Lindane, dieldrin, dichlorodiphenylethane (DDE) and total PCB concentrations detected in sediments exceeded probable effect levels established for freshwater ecosystems, and pp-DDE and total PCB concentrations were higher than effect range-median values developed for marine and estuarine sediments. In fish liver, concentrations of endrin and [sum]DDT exceeded threshold effect level established for invertebrates. [sum]DDT concentrations detected in fish tissues were higher than threshold concentrations for the protection of wildlife consumers of aquatic biota. DDE concentrations in fish muscles tissues were above the 50 ng/g concentration threshold for the protection of predatory birds. Dimethoate, diazinon, malathion, chlorpyrifos, disulfoton varied from [les]0.15 to 9.5 ng/g dry wt in sediments and from [les]0.1 to 80.3 ng/g wet wt in fish tissues. Disulfoton was found in relatively high concentrations (up to 80.3 ng/g) in all organs from Tilapia and Corvina. These results demonstrate continued contamination of specific organochlorine compounds in sediments and resident fish species of the Salton Sea.