CHX & H2O2 - In Vitro, 3% H2O2 and CHX was superior in its antibacterial activity (E. faecalis ) compared with other regimens such as CHX alone and NaOCl.
- Heling & Chandler (1998)
- The combination of the two substances totally killed E. faecalis in concentrations much lower than each component alone.
- Steinberg et al. (1999)
CHX & H2O2 - It can be postulated that the exposure of bacteria to CHX leads to a more permeable cell wall that H2O2 can penetrate easily and hence damage the intracellular organelles.
CHX & H2O2 - There are No reports of clinical studies where the combinations of CHX and H2O2 have been used to disinfect the root canal system.
- Cytotoxicity of the medicament combinations should first be investigated. Interestingly, combinations of CHX and carbamide peroxide have been shown to be additive in their cytotoxicity (Babich et al.1995).
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