Irrigation

NaOCl

• NaOCl

NaOCl

• Antibacterial agent
• Dissolves vital and non-vital tissue. However vital tissue takes longer to dissolve
• Lubricant during instrumentation
• NaOCl has been criticized for
• Unpleasant taste
• Relative toxicity
• Inability to remove smear layer

Bactericidal of NaOCl

• HOCl exerts its effects by oxidizing sulphydryl groups within bacterial enzyme systems, thereby disrupting the metabolism of the microorganism, resulting in the killing of the bacterial cells.
• Unbuffered solution at pH 11 in concentration 0.5–5.25% , and buffered with bicarbonate buffer (pH 9.0) usually as a 0.5% solution (Dakin's solution).