Irrigation

The in vitro studies performed in

• The in vitro studies performed in
• A test tube.
• Root canals of extracted teeth.
• Prepared dentine blocks infected with a pure culture of one organism at a time.
• The in vivo studies, on the other hand, have focused on the elimination of microorganisms from the root canal system in teeth with primary apical periodontitis.

• Antibacterial Studies

Explanation to poorer in vivo performance

• Explanation to poorer in vivo performance
• Root canal anatomy, in particular, the difficulty in reaching the most apical region of the canal with large volumes of fresh irrigant.
• Chemical milieu in the canal is quite different from a simplified test tube environment

• Antibacterial Studies