Volume - The volume of the irrigant has a greater potential to significantly reduce bacteria colonies in root canal.
- Baker et al. 1975, Brown and Doran 1975, Cunningham 1982, Cunningham et al.1982,siqueira at al.2000, Sedgley et al.2005.
Chlorhexidine (CHX) - It possesses a broad-spectrum antimicrobial action and a relative absence of toxicity.
- CHX lacks the tissue-dissolving ability.
- It penetrates the cell wall and attacks the bacterial cytoplasmic or inner membrane or the yeast plasma membrane.
- Concentrations between 0.2% and 2%.
- Its activity is pH dependent and is greatly reduced in the presence of organic matter.
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