Scientific supervisors: prof.Ph.D. H.R.Tukhtaev, ass.M.B.Kosimova
Importance of scientific work: Chamomile flowers and Oak, commonly used in Uzbekistan, are
widely used in folk medicine for germs, ophtalmic diseases, inflammation and allergic effects.
Various cosmetic products, medicinal forms and bone remedies are taken from the plant. In
addition, these benefits are widely used in the complex of various complex drugs. Chamomile and
Oak are in their composition flavonoids apiine, routine,quercimetrine,unbelliferron from coumarins
and gerniarin, essential oils, alkaloids, triterpenes, choline, phytosetrine, ascorbic acid, carotene and
mucus, it is widely used in medicine for disinfectants, anti-inflammatory, stomatitis.
Purpose of the work: Obtain the medicines and their medications, extracted from domestic
ointments and poultry products (Flores Chamomile and Oak bark) used for various diseases of the
mouth and other inflammation, as well as the implementation of the results of these studies in
practice drug science.
Materials and Methods of Study: The result of the analysis show that the quanting of pre-powder
additives increased by 10-11%. Extractively, water and 96% ethyl alcohol (1: 1 ratio) were
extracted to dissolve the biofuels contained in the Calendula and Chamomile flowers. To do this,
the plant was smashed and sifted 1 mm. Reduced to fragments powder, 10 g was taken and 100 ml
of extracting was added and held in a water-bath for 30-45 minutes stored for one day for complete
extraction. The extraction process was repeated 5 times for the removal of the base material, the
filtrate was evaporated, then vaporize state until the total volume reached. To obtain gel, 7 g of Na
(NaCMC), 0.1 g of Chamomile flowers and Oak bark extracts were extracted, 20 g of glycerin, 0.2
nipogine and brought to 100 grams. The gel was taken in brown colour with a homogeneous
consistency.
Results: The storage time for Chamomile fowers and Oak bark was 4 days. After that, the top part
of the tincture was moudly. After edding 5-8% Na(NaCMC) and up to 20% glycerol to the
decoction, the shelf life was 4 months. It was a light yellow gel with consistency of viscous. Three
months later the gel began to lose its viscosity. In order to increase the stability of the gel and
improve its smell and tasty we added nipogin and menthole, after one year, there was no mildew on
the top of the gel. The results revealed that antibacterial activity against the cultures of E. coli and
Bacillussubtillis testicles was found to be 10-15 mm. At the begin we took tincture of Calendula
and Chamomile flower and mixed, obtained the gel and study its the pH value, density and
viscosity.
Conclution: The coraposition of the gel was chosen, which was obtained from a dry extract of
Chamomile and Oak bark, used for diseases of the oral cavity. The Storage period of this drug was
studied. It was found that the saroples were high and effective against E.coli and Bacillussubtillis
(dry extract and gel).
РАЗРАБОТКА ЛЕКАРСТВЕННОГО ПРЕПАРАТА “БАЛЬЗАМА РОДИОЛЫ”
Хаитбоева З. У.,Шаймурадов О. Ш., Асадова Д.А.– студенти 1 го курса
Ташкентский фармацевтический институт, г. Ташкент
Кафедра неорганической, аналитической, физической и коллоидной химии
Руководитель:д.ф.д., доцент Рахматуллаева М.М.
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