Epilepsy and epileptic syndrome


Name of the drug and its synonyms



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Name of the drug and its synonyms


Instructions

Daily dose for older people

Average daily dose for children

Impediment conditions (complete and relatively)

Valproats(depakin,

konvuleks,

orfiril)


All of the epileptic attacks

1200-2400

mg


20-30

mg/kg



Acute and steady hepatitis,

diathesis,

initial 3 months porphyria


Karbamazepin

(finlepsin,

tegretol,

zeptol)



Focal attacks,

Secondary widespread attacks,

Other paroxysms


800-1200

mg


10-20

mg/kg



Atrioventricular conditions, old age brocardia, initial 3 months of pregnancy, blood illnesses, porphyria, hypoterios

Clonazepam

(rivotril,

antelepsin)

Focal is helpful for dealing with widespread attacks

Epileptic status

2-4 mg 1,5-3 mg

pregnancy, lactation,

myasthenia, bronchial asthma. It strengthen miorelacsants, analgesics


Lamotrigin

(lamictal)




focal

initial and secondary attacks

Main thing in

Lennocs-Gasto

Syndrom

Additional drug



100-400

mg


5-10 mg/kg


pregnancy

lack of liver and lung



Gabapentin

(neyrontin)




Focal attacks

1200-2400

mg


20-30

mg/kg



Pregnancy and lactation,

The children under the age of 3



Vigabatrin

(sabril)


Uest syndrom

1000-3000

mg


50-100

mg/kg



Regnancy and lactation

Zonizamid

(zonegran)


Carbamazepine (finlepsin, tegretol, carbalex, zeptol) is used not only in focal epileptic seizures of various etiologies, but also in psychomotor disorders, tonic-clonic seizures observed during sleep or after waking up, abstinence syndrome, manic-depressive psychosis, affective disorders. is used. The dose of the drug is selected individually, depending on the patient's somatic condition, age and course of the disease taken into account (Table 2.34)

2.34-table

Prescription for carbamazepine in epilepsy



The age of patient

Daily minimum dose

Daily maximum dose

Children under the age of 1

100 mg once per day



100 mg twice per day


1-5


100 mg twice in a day


200 mg twice in a day


6-10


200 mg twice in a day


200 mg three times per day


11-15


200 mg three times per day


200 mg four times per day


For adults, 200 mg 4 max per day, hand 400 mg 3-4 times per day



Note: The daily therapeutic dose of carbamazepine for adults can be increased to 1600 - 2000 mg. At such times, retard types of the drug are selected. The patient sometimes forgets to take the daily dose of anticonvulsants. At such times these drugs are long affected species are selected.

Lamotrigine (lamictal, lamitor) is also an effective anticonvulsant, produced in tablets of 25, 50 and 100 mg. Lamotrigine is an effective tonic for clonic seizures and focal seizures. If treatment with other anticonvulsants does not give the desired result, additional lamotrigine is prescribed or it is recommended separately. This drug is also effective in abscesses and myoclonic seizures. The scheme of recommendation of lamotrigine monotherapy is shown in Table 2.35.

Table 2.35

Lamotrigine for children and adults over 12 years of age

monotherapy type recommendation scheme.




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