Webster's New World Medical Dictionary

osteogenesis imperfecta type II
A type of
osteogenesis imperfecta that features very severe
bone fragility. Osteogenesis imperfecta type II is the
lethal form of brittle bone disease. The disease is
characterized by short-limb dwarfism, thin skin, a
soft skull, unusually large fontanels (soft spots),
blue sclerae (bluish whites of the eyes), small nose,
low nasal bridge, inguinal hernia, and numerous
bone fractures at birth. The limbs are bowed due to
multiple fractures. Children with osteogenesis
imperfecta type II are usually stillborn or die in
early infancy. Also known as osteogenesis imper-
fecta congenita and Vrolik disease.
osteogenesis imperfecta with blue sclerae
See 
osteogenesis imperfecta type II.
osteogenic sarcoma
See 
osteosarcoma.
osteoid osteoma
A benign tumor of bone tissue.
Osteoid osteoma emerges most often in a person’s
teens or 20s and is found most frequently in the
femur and in males. Symptoms include pain, mostly
at night. Diagnosis is made via X-ray. Most cases do
not require invasive treatment, but just the use of
analgesics to treat pain.
osteomalacia
Softening of the bone. Osteomalacia
may be caused by poor diet, lack of vitamin D, or
inadequate absorption of calcium and other minerals
needed to harden bones. Treatment includes dietary
change and sometimes vitamin and mineral supple-
ments. See also 
osteoporosis.
osteomyelitis
Inflammation of the bone due to
infection, for example, by the bacteria salmonella or
staphylococcus. Osteomyelitis is sometimes a com-
plication of surgery or injury, although infection can
also reach bone tissue through the bloodstream.
Both the bone and the bone marrow may be
infected. Symptoms include deep pain and muscle
spasms in the area of inflammation, as well as fever.
Treatment includes bed rest, use of antibiotics, and
sometimes surgery to remove dead bone tissue.