Webster's New World Medical Dictionary

leukemia, blastic phase of
A stage in chronic
myeloid leukemia in which 30 percent or more of
the cells in the bone marrow or blood are the malig-
nant blast cells. See also 
leukemia, chronic
myeloid.
leukemia, chronic lymphocytic
The most
common form of leukemia in adults, in which lym-
phocytes look fairly normal but are not fully mature
and do not function correctly against infection. The
malignant cells are found in blood and bone mar-
row, collect in and enlarge the lymph nodes, and
may crowd out other blood cells in the bone mar-
row, resulting in a shortage of red cells (producing
anemia) and platelets (producing bleeding and
bruising). Abbreviated CLL. CLL is most common in
people 60 years of age or older, and it progresses
slowly. In the first stages of CLL, there are often no
symptoms. As time goes on, more and more lym-
phocytes are made and symptoms begin to appear.
Treatments may include chemotherapy, monoclonal
antibody therapy, and bone marrow transplantation.
leukemia, chronic myelogenous
See
leukemia, chronic myeloid.
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leukemia, chronic myelogenous
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leukemia, chronic myeloid
A malignant dis-
ease involving the white blood cells belonging to the
myeloid line that is due to a chromosome
rearrangement called the Philadelphia (or Ph)
chromosome translocation. Abbreviated CML. CML
has several phases that succeed one another. In the
first phase, the chronic phase, there are few blast
cells in blood and bone marrow and there may be
no symptoms. This phase may last from several
months to several years. In the next phase, the
accelerated phase, there are more blast cells in
blood and bone marrow and fewer normal cells. In
the final phase, the blastic phase (or blast crisis),
more than 30 percent of the cells in the blood or
bone marrow are blast cells. Treatments may
involve chemotherapy and bone marrow transplan-
tation. Also called chronic myelocytic leukemia and
chronic granulocytic leukemia.