Webster's New World Medical Dictionary

GM2-gangliosidosis
One of a group of genetic
lipid storage disorders that affect the brain. The
main types of GM2 gangliosidoses are Tay-Sachs dis-
ease and its variants (due to hexosaminidase A defi-
ciency) and Sandhoff disease and its variants (due
to hexosaminidase B deficiency). See also 
Sandhoff
disease; Tay-Sachs disease.
goiter
A noncancerous enlargement of the thy-
roid gland. With a goiter, the levels of thyroid hor-
mones may be normal (euthyroid), elevated
(hyperthyroidism), or decreased (hypothyroidism).
goiter, diffuse toxic
See 
Graves disease.
goiter, exophthalmic
See 
Graves disease.
goiter, iodide
A goiter caused by prolonged
intake of too much iodine that results in abnormally
low thyroid activity (hypothyroidism). Certain foods
and medications contain large amounts of iodine.
Examples include seaweed; iodine-rich expecto-
rants (Brand names: SSKI and Lugol solution) used
in the treatment of cough, asthma, and chronic pul-
monary disease; and amiodarone (brand name:
Cardorone), an iodine-rich medication used in the
control of abnormal heart rhythms.
goiter, toxic multinodular
A condition in
which the thyroid gland contains multiple lumps
(nodules) that are overactive and that produce
excess thyroid hormones. Also known as Parry dis-
ease and Plummer disease.
goiter-deafness syndrome
See 
Pendred 
syndrome.
golfer’s cramp
A dystonia that affects the mus-
cles of the hand and sometimes the forearm and
that occurs only when a person is playing golf.
Similar focal dystonias have also been called typist’s
cramp, pianist’s cramp, musician’s cramp, and
writer’s cramp. See also 
dystonia; dystonia, focal.