Universum: технические науки

3.1.2. Dextran:
carboxymethyl benzyl amide sul-
fonate dextran (CMBDS) is widely used in wound heal-
ing and various biomedical applications and its proper-
ties are heparin-like and soluble. Glycosaminoglycan 
stimulates wound healing in various parts of the body. It 
has antimicrobial properties, especially in the prolifera-
tion of Staphylococcus aureus. It also has a specific ef-
fect on the proliferation of tumor cells. Aqueous cy-
clodextrins used to control odors in modern dress-
ings[5]. 
3.1.3. Collagen
: It is a protein, found outside the 
cell, and is often composed of proline, hydroxyl-proline 
glycine, and arginine. It is made of fibroblasts, and it en-
ters the scaffolds of some tissue engineering, such as 
bone, cartilage, and tendons, for their biocompatibility, 
and their biodegradability, and provides[4] strength to 
various body structures. It also enters in all stages of 
wound healing due to the decrease of its antigenic prop-
erties and the adhesion of cells directly to it[6]. It pro-
tects the body from diseases by preventing absorption 
and dispersion. Pathogenic substances such as UV rays, 
microorganisms and cancer cells. It obtained from the 
hides of cows, pigs and chickens, as well as from ocean 
animals such as octopus.[4, 6, 7]. 
3.1.4. Gelatin:
derived from collagen, and obtained 
through the hydrolysis of animal tissues such as the skin 
of cows and pigs. It is biologically compatible and bio-
degradable and not attacked by the immune system. It 
divided into gelatin A, which derived from acidic treated 
materials and contains the isoelectric point (positive 
charge at the neutral pH)
[
5
]
. In addition, gelatin B is 
derived from alkali-treated materials and contains the 
isoelectric point (negative charge at the neutral pH). It 
used as a scaffold for tissue engineering, also in the de-
livery of the drug, as many of the capsules that are deliv-
ered orally are gelatin; gelatin and some other natural pol-
ymers have been studied in the laboratory and in the 
body that can deliver the pulmonary drug[4]
.
[
7
]

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3.1.5.Chitosan
: Cationic polymer derived from chi-
tin (polysaccharide). It contains a common polymer of 
β-glucosamine and N-acetyl-D-glucosamine. It is the 
second most abundant natural polymer after cellulose
.
[
4
]
Chitosan is suitable for binding with red blood cells that 
allow them to rapidly coagulate blood ، modify the func-
tion of inflammatory cells and act as a semi-permeable bi-
ological dressing ، maintains sterile ، regenerated and bi-
ologically compatible wound secretions ، and not at-
tacked by the immune system and nontoxic system[5, 6]. It 
also induces fibroblasts to secrete the interleukins and 
the latter works in the migration and spread of cells. 
The(2) most important characteristics that make chi-
tosan important in healing[5, 7] .