The word Pharmacology is derived from Greek words pharmakon (=drug= remedy= to do good) and logos

Basics of PHARMACOLOGY

The word Pharmacology is derived from Greek words pharmakon (=drug= remedy= to do good) and logos (= a study = science)

• The word Pharmacology is derived from Greek words pharmakon (=drug= remedy= to do good) and logos (= a study = science)

BASIC PHARMACOLOGY

• Definition: Pharmacology is a subject of medical science which deals with the study of drugs or medicine that interact with the living system through chemical processes, specially by binding to regulatory molecules and activating or inhibiting body process.
• Medical Pharmacology: Branch of Pharmacology deals with the use of Drugs in human body for Diagnosis, Prevention, Suppression and Treatment of the Diseases.
• Clinical Pharmacology: Deals with the Scientific study of Drugs( Pharmacokinetics & Pharmacodynamic parameters) in the patients & also in the healthy persons for the safe & effective use of Drugs (Therapy).

Pharmacokinetics

Greek word-Pharmakon means drug, Kinein means: To move

It deals with-

• Absorption – taken into the body
• Distribution – moved into tissues
• Metabolized – changed so can be excreted
• Excreted – removed from the body

ABSORPTION OF DRUG

The process by which the drug enters into the systemic circulation from the site of administration ( except intravenous or intra-arterial routes ) through the biological membrane is called absorption of drug .

• In case of intravenous or intra-arterial administration the drug is not absorbed and it enters into the circulation directly .

DISTRIBUTION OF DRUG

All the consequences of delivery of drug to the tissue is called distribution of drug. Distribution of drug means dividing and spreading of drug to the tissue.

• Selective distribution of drug: It means special distribution of drug in the certain tissue of the body due to special affinity between particular drug & particular body constituents