SylbV01-00-00. pmd

VI. Theory
Unit I
Genetic material, cell division, chromosomes, nucleic acids, biological significance
of DNA, Mendelian principles I and II, calculation of genetic ratios, Chi-Square
method, dominance, Gene Interaction, multiple alleles, sex determination,
extranuclear inheritance, quantitative inheritance, linkage and recombination,
genetic map, environmental effects – external and internal, phenocopies,
concordance, discordance, epigenetics, environmental epigenetics, DNA methylation,
histone modification, gene environment vs epigene environment, epigenetic
inheritance.
Unit II
Modern Synthesis Theory – Endangered and extinct species – causes of extinctions –
Structure and content of conservation genetics – genetics and extinctions – Genetic
versus demographic and environmental factors in conservation biology – Limitations
of Genetics in Conservation Biology.
Unit III
Hardy Weinberg Principle, proportions – deviations from Hardy–Weinberg
equilibrium, Inbreeding – Assortative and dissassortive mating, extensions of
Hardy –Weinberg equilibrium, evolutions in large population, natural selection
and adaptation, directional, stabilizing and disruptive selection, mutation, migration
and their interaction, evolution in small population, genetic drift, inbreeding,
inbreeding depression, outbreeding, outbreeding depression, population
fragmentation, gene flow.
Unit IV
Genetically viable populations, reproductive fitness, population viability analysis,
recovery of endangered species/ threatened population, legal issues related to
endangered species and their protection, minimum viable population, recovery of
endangered species, legal issues related to endangered species and their protection.
VII. Practical
• Deriving Hardy Weinberg equilibrium, problems on Hardy Weinberg equilibrium,
calculation of gene frequencies, autosomal loci with two alleles, estimation of gene
frequencies, autosomal loci with multiple alleles, estimation of gene frequencies;
• Sex linked loci, estimation of inbreeding co-efficient – problems in epigenetics,
genetic variability of threatened populations, hybridization and introgression
analysis;
• Plant forensics, storage of plant genetic samples for time-series analyses.