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A CLINICIAN’S GUIDE TO DERMATOLOGIC DIFFERENTIAL DIAGNOSIS, VOLUME 1



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[Encyclopedia of Differential Diagnosis in Dermatology] Paul Schneiderman, Marc E. Grossman - A Clinician\'s Guide to Dermatologic Differential Diagnosis, Volume 1 The Text (Encyclopedia of Differential Diagnosis in D

654
A CLINICIAN’S GUIDE TO DERMATOLOGIC DIFFERENTIAL DIAGNOSIS, VOLUME 1
Schneiderman page 600-722.qxd 5/16/2006 6:51 PM Page 654


Cryptococcosis – punched out ulcers with rolled edge 
NEJM
347:1412–1418, 2002; AD 124:429–434, 1988; AD
112:1734–1740, 1976; BJD 74:43–49, 1962; AD 77:210–215,
1958; verrucous ulcer Cutis 51:377–380, 1993; herpetiform
ulcers
JAAD 10:387–390, 1984; mimicking pyoderma
gangrenosum 
JAAD 5:32–36, 1981
Curvularia lunata – sternal wound infection with chest ulcer
J Clin Inf Dis 19:735–740, 1994; Arch Int Med 139:940–941, 1979
Cytomegalovirus
Dermatology 200:189–195, 2000;
JAAD 38:349–351, 1998; J Rheumatol 20:155–157, 1993;
AD 127:396–398, 1991
Dematiacious fungal infections in organ transplant recipients –
all lesions on extremities
Alternaria
Bipolaris hawaiiensis
Exophiala jeanselmei, E. spinifera, E. pisciphera, E. castellani
Exserohilum rostratum
Fonsacaea pedrosoi
Phialophora parasitica
Diphtheria – superficial round ulcer with overhanging edge;
gray adherent membrane; later edge thickens and becomes
raised and rolled; umbilicus, post-auricular, groin, finger or toe
web; heals with scarring; crusts around nose and mouth with
faucial diphtheria 
Schweiz Rundsch Med Prax 87:1188–1190,
1998; Postgrad Med J 72:619–620, 1996; Am J Epidemiol
102:179–184, 1975
Dracunculosis – small papule or vesicle which ruptures;
ulcer forms from which worm can be removed 
Dermatol
Clinic 7:323–330, 1989
Escherichia coli
Ecthyma – streptococcal or staphylococcal; ulcer with thick
hard crust 
Rook p.1112, 1998, Sixth Edition; eschar and
ulceration 
JAAD 47:766–769, 2002
Ecthyma gangrenosum – 
Pseudomonas aeruginosa, Candida,
Aspergillus, Escherichia coli, Aeromonas hydrophila
Filariasis – elephantiasis of the dorsum of the foot with
ulceration 
Caputo p.162, 2000
Fusarium solanae Rev Soc Bras Med Trop 30:323–328, 1997
(
Spanish); Sabouradis 17:219–223, 1979
Glanders – 
Pseudomonas mallei – cellulitis which ulcerates
with purulent foul-smelling discharge, regional lymphatics
become abscesses; nasal and palatal necrosis and destruction;
metastatic papules, pustules, bullae over joints and face, then
ulcerate; deep abscesses with sinus tracts occur; polyarthritis,
meningitis, pneumonia; eschar and ulceration; ulceroglandular
JAAD 47:766–769, 2002; Rook p.1146–1147, 1998, Sixth
Edition
Gram-negative web space infection
Granuloma inguinale – papule or nodule breaks down to form
ulcer with overhanging edge; deep extension may occur; or
serpiginous extension with vegetative hyperplasia; pubis,
genitalia, perineum; extragenital lesions of nose and lips, or
extremities 
JAAD 11:433–437, 1984
Herpes simplex
NEJM 347:1412–1418, 2002; Tyring p.86–87,
2002; AD 132:1157–1158, 1996; JAMA 241:592–594, 1979;
neonatal HSV – widespread erosions 
Tyring p.89, 2002; J
Pediatr 101:958–960, 1982; congenital absence of skin J
Pediatr 101:958–960, 1982; ulceroglandular disease JAAD
47:766–769, 2002
Herpes zoster – chronic ulcerating acyclovir-resistant varicella
zoster 
Scand J Infect Dis 27:623–625, 1995
Histoplasmosis 
AD 132:341–346, 1996; JAAD 29:311–313,
1993; Medicine 60:361–373, 1990; Cutis 43:535–538, 1989;
punched out ulcers 
Arch Derm Syphilol 56:715–739, 1947
Impetigo
Insect bites – eschar and ulceration 
JAAD 47:766–769, 2002
Kerion
Leishmaniasis 
JAAD 51:S125–128, 2004; Clin Inf Dis
33:815,897–898, 2001; Clin Inf Dis 32:1304–1312, 2001; Trans
R Soc Trop Med Hyg 81:606, 1987; Cutis 38:198–199, 1986;
mucocutaneous leishmaniasis 
J Emerg Med 20:353–356,
2001; AD 134:193–198, 1998; J Clin Inf Dis 22:1–13, 1996;
kala-azar – 
Leishmania donovani – pedal edema; primary
ulcer; hyperpigmented skin of face, hands, feet abdomen
Rook p.1419, 1998, Sixth Edition; leishmaniasis recidivans –
crusted ulcer 
Clin Inf Dis 33:1076–1079, 2001; eschar and
ulceration 
JAAD 47:766–769, 2002
Leprosy (
Mycobacterium leprae) – lepromatous leprosy
Int J Dermatol 29:156–157, 1990; plantar ulcers due to
involvement of common peroneal and posterior tibial nerve
leading to foot drop 
Indian J Lepr 71:437–450, 1999;
neurotrophic ulcers 
Rook p.2265, 1998, Sixth Edition; Lucio’s
phenomenon – generalized ulcers 
AD 135:983–988, 1999;
Rook p.1227, 1998, Sixth Edition; eschar and ulceration JAAD
47:766–769, 2002; painless ulcers JAAD 48:958–961, 2003;
immune reconstitution inflammatory syndrome (IRIS) in HIV
disease – ulcerated plaque 
AD 140:997–1000, 2004; tender
ulcerations of buttocks and legs 
AD 116:201–204, 1980
Lobomycosis
Lymphogranuloma venereum – ulceroglandular disease
JAAD 47:766–769, 2002
Meleney’s synergistic gangrene 
Rook p.2265,2266, 1998,
Sixth Edition
Melioidosis – 
Burkholderia pseudomallei ; septic arthritis,
abscesses, ulcers 
Clin Inf Dis 31:981–986, 2000;
ulceroglandular disease 
JAAD 47:766–769, 2002; ulcerative
vegetative plaque 
Cutis 72:310–312, 2003
Meningococcemia – necrotic purpura with ulcerations 
Pediatrics
60:104–106, 1977
Milker’s nodule – eschar and ulceration 
JAAD 47:766–769, 2002
Mosquito bite hypersensitivity syndrome in Epstein–Barr
virus-associated natural killer cell leukemia/lymphoma – clear
or hemorrhagic bullae with necrosis, ulceration and
scar formation 
JAAD 45:569–578, 2001
Mucormycosis
Clin Inf Dis 19:67–76, 1994; JAAD 21:1232–1234,
1989; eschar and ulceration JAAD 47:766–769, 2002
Mycetoma
Mycobacterium avium-intracellulare BJD 142:789–793, 2000;
BJD 136:260–263, 1997; Clin Inf Dis 19:263–273, 1994; JAAD
19:492–495, 1988; ecthyma-like ulcer AD 126:1108–1110, 1990
Mycobacterium chelonae Clin Inf Dis 19:263–273, 1994;
AD 129:1190–1191, 1193, 1993; post-surgical wound infection
J Infect Dis 143:533–542, 1981
Mycobacterium fortuitum Clin Inf Dis 19:263–273, 1994;
post-surgical wound infection 
J Infect Dis 143:533–542, 1981
Mycobacterium haemophilum – necrotic ulcer Clin Inf
Dis 33–330–337, 2001; Rook p.1213, 1998, Sixth Edition;
Clin Inf Dis 19:263–273, 1994; J Infection 23:303–306, 1991;
inguinal ulcer 
AD 138:229–230, 2002
Mycobacterium kansasii JAAD 36:497–499, 1997; Clin Inf
Dis 19:263–273, 1994; swollen fingers with ulcers JAAD
45:620–624, 2001
Mycobacterium marinum – ecthyma-like ulcers Clin Inf Dis
19:263–273, 1994; ulcers mimicking M. ulcerans Med J Austral
ii:434–437, 1973
Mycobacterium scrofulaceum Clin Inf Dis 20:549–556, 1995;
Clin Inf Dis 19:263–273, 1994

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