Schneiderman Prelims Vol-I. qxd

INFILTRATIVE DISEASES
Amyloidosis
Langerhans cell histiocytosis
INFLAMMATORY DISEASES
Erythema multiforme
Post-inflammatory hypopigmentation – in blacks, especially after
dermatitis, sarcoidosis, leprosy, herpes zoster, tinea versicolor,
cryotherapy, topical or injected corticosteroids 
Textbook of
Neonatal Dermatology, p.364, 2001; Int J Dermatol 29:166–174,
1990; vulvar Genital Skin Disorders, Fischer and Margesson,
CV Mosby p.189,193, 1998
Pseudolymphoma – CD8
+
pseudolymphoma in HIV disease;
widespread hypopigmentation 
JAAD 49:139–141, 2003
Sarcoid 
AD 138:259–264, 2002; AD 123:1557–1562, 1987;
Am J Med 35:67–89, 1963
Sympathetic ophthalmia
METABOLIC
Acrodermatitis enteropathica with anorexia nervosa –
hypopigmented hair 
JAMA 288:2655–2656, 2002
Addison’s disease – vitiligo-like patches 
Rook p.1807, 1998,
Sixth Edition
Homocystinuria – skin and hair hypopigmentation 
JAAD
40:279–281, 1999
Hypopituitarism – diffuse loss of pigment 
Rook p.1807,2704,
1998, Sixth Edition
Hypothyroidism – pale, cold, scaly, wrinkled skin 
Rook p.1807,
1998, Sixth Edition; JAAD 26:885–902, 1992
Kwashiorkor – hypochromotrichia and hypopigmentation of skin
Cutis 67:321–327, 2001; Cutis 51:445–446, 1993
Liver disease, chronic – spotty hypopigmentation on back,
buttocks, and thighs; may be in relation to spider telangiectasias
Rook p.2725, 1998, Sixth Edition
Malabsorption 
Ghatan p.248, 2002, Second Edition
Pernicious anemia – vitiligo, canities 
Rook p.1783, 1998,
Sixth Edition
Phenylketonuria – phenylalanine hydroxylase deficiency; fair
skin and hair 
Rook p.2645, 1998, Sixth Edition
HYPOPIGMENTED PATCHES OR PLAQUES
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Prolidase deficiency 
Ghatan p.248, 2002, Second Edition
Renal disease – nephrosis 
Ghatan p.248, 2002, Second Edition
Selenium deficiency – loss of pigmentation of hair and skin
Cutis 61:229–232, 1998
Vitamin B
12
deficiency (pernicious anemia) – premature canities
Cutis 71:127–130, 2003