Schneiderman Prelims Vol-I. qxd

NEOPLASTIC DISORDERS
Epidermal nevus – secreting LHRH – hirsutism
Melanocytic nevus – giant congenital melanocytic nevus 
Ped
Derm 18:369–377, 2001
Giant nevoid hypertrichosis 
Ped Derm 19:64–66, 2002
PARANEOPLASTIC DISORDERS
Hypertrichosis lanuginosa acquisita (malignant down) – 41
cases; lung, colon carcinomas most common; also breast, gall
bladder, uterus, urinary bladder if accompanied by acanthosis
nigricans; the malignancy is always an adenocarcinoma 
J Surg
Oncol 68:199–203, 1998; AD 122:805–808, 1986
PRIMARY CUTANEOUS DISEASES
Epidermolysis bullosa, dystrophic 
Bolognia p.1053, 2003
Prepubertal hypertrichosis 
Textbook of Neonatal Dermatology,
p.495–496, 2001
Primary generalized hypertrichosis (hypertrichosis lanuginosa
congenital, congenital generalized hypertrichosis, universal
hypertrichosis) 
AD 137:877–884, 2001; Clin Genet 10:303–306,
1976
PSYCHOCUTANEOUS DISORDERS
Eating disorders – anorexia nervosa, bulemia nervosa –
increased lanugo body hair 
Ped Derm 18:57–59, 2001;
Int J Derm 39:348–353, 2000; Ped Derm 16:90–94, 1999
Schizophrenia 
Ghatan, Second Edition, 2002, p.69
SYNDROMES
Acromegaloid facial appearance and generalized hypertrichosis
J Med Genet 33:972–974, 1996
Acro-osteolysis (Hajdu–Cheney syndrome) 
Birth Defects
10:106–123, 1974
Ambras syndrome – unique hypertrichosis universalis congenita
Clin Genet 44:121–128, 1993
Barber–Say syndrome – macrostomia, hypertelorism, atrophic
skin, hypertrichosis, ectropion 
Am J Med Genet 73:366–367,
1997; Am J Med Genet 47:20–23, 1993
Berardinelli’s (Berardinelli–Seip) syndrome – lipodystrophy with
muscular hypertrophy; coarse hypertrichotic skin 
J Clin
Endocrinol Metab 14:193–204, 1954
Cantu syndrome – congenital hypertrichosis, cardiomegaly,
osteochondrodysplasia, coarse facial features, deep plantar
creases 
Am J Med 92:191–194, 2000; Am J Med Genet
94:421–427, 2000; Am J Med Genet 69:138–151, 1997
Cataract, hypertrichosis, and mental retardation – autosomal
recessive 
Am J Med Genet 41:432–433, 1991
Cerebral malformation, seizures, hypertrichosis, distinct face,
claw hands, and overlapping fingers 
Am J Med Genet
47:698–701, 1993
Coffin–Siris syndrome – hypertrichosis of the face and body,
bushy eyebrows, lumbosacral hirsutism; coarse facial features,
low birthweight, retarded growth, mental retardation, hypoplastic
or absent fifth fingernails and toenails 
J Med Genet
27:333–336, 1990; Am J Dis Child 132:1044, 1978
Cone–rod congenital amaurosis associated with congenital
hypertrichosis 
J Med Genet 26:504–510, 1989
Congenital cataracts, sensorineural deafness, hypogonadism,
hypertrichosis, short stature 
Clin Dysmorphol 4:283–288,
1995
Cornelia de Lange (Brachmann–de Lange) syndrome –
generalized hypertrichosis, confluent eyebrows, low hairline,
hairy forehead and ears, hair whorls of trunk, cutis marmorata,
single palmar crease, physical and mental retardation
Am J Med Genet 47:959–964, 1993
Costello syndrome – generalized hypertrichosis; warty papules
around nose and mouth, legs, perianal skin; loose skin of neck,
hands, and feet; acanthosis nigricans; low set protuberant ears,
thick palmoplantar surfaces with single palmar crease, gingival
hyperplasia, hypoplastic nails, moderately short stature,