Schneiderman Prelims Vol-I. qxd

EXOGENOUS AGENTS
Accidental tattoos
Argyria – silvery or slate-gray pigmentation of sun-exposed
areas (forehead, nose, hands); may be generalized 
Rook
p.1794, 1998, Sixth Edition; Am J Kidney Dis 37:1048–1051,
2001; BJD 104:19–26, 1981; AD 114:373–377, 1978;
exogenous argyria 
BJD 144:191–192, 2001
Chloracne – halogenated aromatic hydrocarbons –
chloronaphthalenes, chlorobiphenyls, chlorobiphenyl oxides
used as dielectrics in conductors and insulators, chlorophenols
in insecticides, fungicides, herbicides, and wood preservatives
Am J Ind Med 5:119–125, 1989
Cigarette smoking – brown teeth, fingers 
Rook p.3051, 1998,
Sixth Edition
Clothing dermatitis – pigmentation in flexures 
Rook p.1794,
1998, Sixth Edition
Coal tar products – pitch, asphalt, creosote – diffuse melanosis
of exposed skin; evolves to atrophy, telangiectasia, lichenoid
papules, follicular keratosis 
Rook p.1791, 1998, Sixth Edition
Collier’s stripes
Copper – green hair from swimming-pool algicides, copper
household pipes 
Cutis 56:37–40, 1995; green skin – copper
bracelet, copper eyeglass frames
Drug abuse 
NEJM 277:473–475, 1967; soot tattooing NY State
J Med 68:3129–3134, 1968
Ferric sulfate, ferric chloride – red–brown tattoo 
Rook p.1813,
1998, Sixth Edition
Formaldehyde – gray nails 
Ghatan p.78, 2002, Second Edition
Gentian violet – purple nails; gray nails 
Ghatan p.79, 2002,
Second Edition
Green hair – copper exposure
Herbal potions 
Int J Dermatol 30:186–189, 1991
Hydroquinone – topical; exogeneous ochronosis; gray nails
Ghatan p.78, 2002, Second Edition
Iodine – brown nails 
Ghatan p.78, 2002, Second Edition
Jewelry cleanser – hypo- and hyperpigmentation
Mercury – skin lightening creams in skin folds and eyelids
JAAD 39:524–525, 1998; Int J Dermatol 30:186–189, 1991
Nail polish, nail hardeners – brown or orange
hyperpigmentation 
Ghatan p.78, 2002, Second Edition