Python Programming for Biology: Bioinformatics and Beyond

12

13

‘Student’ was a pseudonym of William Gosset, who discovered the distribution while

working for the Guinness brewery in the early twentieth century.

14

The T-statistic for Welch’s T-test is:

.

15

Mentioned in

Chapter 11

to measure the repetitiveness of a sequence.

16

It also follows that r

2

is the coefficient of determination: the fraction of the variance in

Y that is explained by X.

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23

Clustering and discrimination

Contents

Separating and grouping data

Vector data units

Discrimination

Clustering

Clustering methods

Simple threshold clustering

Density-based clustering

K-means clustering

Improving k-means

The ‘jump’ method

Data discrimination

Principal component analysis

Extracting a principal component

Linear discriminant analysis