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  Synthesis of 1-chlorine-3-piperidine-2-propanol



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Сборник журналя Техника Инновэйшн

1. 
Synthesis of 1-chlorine-3-piperidine-2-propanol
The process of amino alcohol synthesis based on piperidine and epichlorohydrin occurs 
exothermically. In this case, the interaction of piperidine with epichlorohydrin (EXG) was 
carried out at a relatively low temperature in an aqueous medium. The reason why the 
crosslinking reaction of piperidine and epichlorohydrin was studied at temperatures of -1 to -5 

C was that the temperature was kept negative at higher temperatures to prevent the formation of 
quaternary ammonium oligomers and amino alcohol synthesis, and 1-chlorine-3-piperidine-2-
propanol (XPP) was synthesized [12] . 
 
 
 
 
 
 
2. Synthesis of monomer 1-chlorine-3-piperidine-2-propylmethacrylate
 
Following the 1-chlorine-3-piperidino-2-propanol molecule gidroksil the existence of the 
group and it is because of the relatively weak nucleophiles characteristic ON-group combination 
reactions expected to participate in this section of the above synthesized 1-chlorine-3-piperidin- 
The process of synthesis of unsaturated esters based on the et t erification reaction of methacrylic 
acid with 2-propanol was studied [13] . The reaction was carried out at a temperature of 80 


for 3 h. The synthesis processes of 1-chlorine-3-piperidine-2-propyl methacrylate were studied. 
The esterification reaction of methacrylic acid with 1-chlorine-3-piperidine-2-propanol can be 
expressed by the following scheme: 
 
 
 
 
3. The method of polymerization of the monomer
 
N CH CH
CH Cl
OH
2
2
CH C
CH
COOH
2
3
-
HOH
N CH CH
CH Cl
O C C
O
CH
CH
2
2
3
2
N
H
+
CH
Cl
O
CH CH
2
2
H
2
O
N
CH
CH
OH
CH
2
2
Cl
+



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