Advances in Molecular Electronics: a brief Review

Antimicrobial Studies 
The toxic activities of ETO-NPs against the DNA destruction of 
chosen bacteria and fungus are studied using the disk diffusion 
technique [26,27]. The concentrations of ETO-NPs powder such 
as 100, 200, and 300 mg are tested against microbial pathogens, 
further; the observed result was tabulated to reveal the effective 
toxic activity of synthesized ETO-NPs. 
Cytotoxicity and MTT Assays 
The cytotoxic effects of ETO-NPs were quantified with 
colorimetric assay by using the MTT method [3-(4,5-
dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide]. In this 
section cytotoxicity of ETO-NPs at different concentrations (5, 
10, 20, 25, and 50 μg/ml) and further at different periods of 
incubation (24 and 48 h) were tested 1.5×10
3
MDA-MB- 231 
cells per well in 96 wells plates were kept and incubated at 37 μC/ 
with the presence of 5% CO2. After 48 hour period of incubation, 
20 μl of MTT solution (5 mg ml−1 in PBS) was added to each 
well and maintained without light radiation for a period of 4 h and 
have 100 μl of DMSO mixed formazan crystals (insoluble in 
water). The cytotoxicity of ETO-NPs against cancer-producing 
cells was noted with the help of absorbance of 590 nm 
wavelength of radiation using an ELISA reader (Tecan, Austria). 
The untreated (without ETO-NPs) medium having 0.1% vehicle 
DMSO acted as the negative control. The ant proliferative activity 
of ETO-NPs was expressed in terms of IC50 values and this 
concentration and causes a 50% inhibition of cell growth. 
Results and Discussion 
XRD 
With the help of XRD analytical technique, XRD spectrum has 
been obtained which is useful for the analysis of nano-crystalline 
structures, qualitative identification and particle sizes of ETO-
NPs as well as inorganic catalysts, superconducting materials, 
bio-based molecules, ceramic glasses, and polymers, etc [28]. In a 
powdered sample containing ETO-NPs, the beam of x-ray 
radiation typically diffraction peaks agree well with the phase 
structure of ETO-NPs. The XRD spectrum (Figure 1) of the ETO-
NPs confirmed that the crystalline nature of the ETO-NP belongs 

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Citation:
Gopal S Iruson B Balaraman S Krishnmoorthy S and Elayaperumal M. (2021) Structural and Evaluations of Rare Earth Erbium Try Oxide 
Nanoparticles and Their Health Impacts on Workers. Global J Mater Sci Eng 3(3): 123 DOI: 
https://doi.org/10.36266/GJMSE/123
 
Pubtexto Publishers | www.pubtexto.com 3
Global J Mater Sci Eng
to a body-centered cubic structure which was well matched with 
the standard JCPDS No. 77-0777. The average crystallite size of 
ETO-NP is calculated as 62 nm by using Debye - Scherer’s 
formula. 
Figure 1:
 The XRD pattern of ETO-NPs (This graph predicts the 
existence of miller indices of ETO-NP crystalline powder containing all 
possible lattice planes).