Length of course



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Bog'liq
PATH-438

7
th
 Week:
The instructor will present pharmacological applications—hypoglycemic 
drugs, metformin, glitazones, and sulfonylureas. Instructor will lead discussion of 
holistic management of prediabetic state and metabolic syndrome. 
8
th
 Week: 
The instructor will present pharmacological applications—anxiolytic drugs, 
benzodiazepines, antidepressant drugs, SSRIs/SNRIs, MAOIs and serotonin 
syndrome. 
9
th
 Week: 
The instructor will present pharmacological applications—pain 
medications, NSAIDs, opioids, neurogenic analgesic drugs, salicylism, 
eicosanoid chemistry, 
cox-2
inhibitors, respiratory burst and inflammatory 
response.
 


Submitted OAA/Department September 
2019 
5
 
|
 
Page
10
th
 Week: 
The instructor will present the anti-oxidation system—enzymes 
(catalase, SOD, Glutathione peroxidase), antioxidant vitamins, PUFAs and lipid 
peroxidation. Review and preparation for final exam. 
11
th
 Week: Final Exam.
Student Learning Outcomes 
This course aligns to PLOs:
(1 and 3) 
Upon the successful conclusion of this course, the student should be able to 
1. Understand and apply pharmacokinetic and pharmacodynamic principles that impact 
administration, absorption, distribution, metabolism, elimination, efficacy, potency, 
effectiveness and biological activity of drugs and toxins.
2. Understand and describe how the liver’s cytochrome P
450
system works, including 
Biotransformation Phases I and II, and how drug-drug and drug-herb interactions 
affect this detoxification system.
3. Understand the therapeutic and adverse effects of selected drugs, supplements, and 
environmental toxins.
4. Understand and identify health conditions linked to selected toxic exposures from 
food, lifestyle, environment, workplace and home.
5. Understand the role of toxicology in the development and progression of disease 
and to characterize its impact on patient response to chiropractic care.

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