Irrigation

Is NaOCl equally effective in dissolving vital, non-vital, or fixed tissue ???

• Demonstrated that 5.25% sodium hypochlorite dissolves vital tissue. (Rosenfeld et al. 1978 )
• As a necrotic tissue solvent, 5.25% sodium hypochlorite was found to be significantly better than 2.6%, 1%, or 0.5%. (Hand et al.1978)
• 3% sodium hypochlorite was found to be optimal for dissolving tissue fixed with parachlorophenol or formaldehyde (Thé SD.1979)

NaOCl & Other Medicaments

• The antibacterial efficacy of sodium hypochlorite, is increased when it is used in combination with other solutions, such as calcium hydroxide, EDTAC, or chlorhexidine.
• Possibly,the bactericidal effect gained by combining sodium hypochlorite with other chemicals comes from the release of chlorine gas.

NaOCl & Other Medicaments

NaOCl & Ca(OH)2

• Pretreatment of tissue with calcium hydroxide can enhance the tissue-dissolving effect of sodium hypochlorite.
• Hasselgren et al.(1988)
• Combination of calcium hydroxide and sodium hypochlorite was more effective on the dissolution of soft tissue on the root canal wall than using either medicament alone.
• Wadachi et al.(1998)