I n t e r n a L medicine questions Bank

) All the following are mechanism – drug induced Hyperkalemia except :

1. 
   Trimethoprim inhibits Na channels
   
2. 
   yclosporin and Cl shunting
   
3. 
   Heparin decreases Aldosterone level
   
4. 
   Digoxin inhibits K-ATP ase
   
5. 
   NSAID blocks PG stimulated Renin secretion
   

2. 
   35 year old female is evaluated because of an elevated Bp 160/105 for the past 2-3 months . Her mother has hypertension and kidney disease , and a maternal aunt is now on hemodialysis
   

Labs : Cr 0.8 mg/dl , Na 140 meq/ L , K 5.0 meq /L , Cl 102 meq / L , HCO3 25 MEQ / l , Urine Analysis is negative .
Which of the following is most likely to provide information regarding cause of her hypertension .

1. 
   Captopril Renal Scan
   
2. 
   24 hour urine for Vanillyl Mandellic Acid
   
3. 
   Renal U/S
   
4. 
   Plasma Renin activity & aldosterone level Plasma PTH
   

6. 
   ) All the following are Renal changes expected in normal pregnancy except :
   

1. 
   Dilation of pelvicaliceal system
   
2. 
   Serum HCO3 is 4-5 mmol/L higher than normal
   
3. 
   GFR increase by 35-50 %
   
4. 
   Serum osmolality decreases by 10 mosmol/L Renal length increases by 1 cm on U/S
   

6. 
   ) 50 year old man has history of recurrent kidney stones which were Ca containing stones .
   

1. 
   All of the following are risk factors for formation of these stones except :
   
2. 
   Hypercalciuria
   
3. 
   Hyperoxaluria
   
4. 
   Low urine volume
   
5.