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Rheumatology and bone disease



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MU-MCQs-Internal-medicine (2022)

Rheumatology and bone disease


  1. What is swan neck deformity in RA :

  1. Hyper flextion of proximal interphalangal (PIP) and hyper extension of distal interphalangal (DIP).

  2. Hyper extension of PIP and hyper flextion of DIP. C)Hyper extension of PIP and hyper extension of DIP. D)Sublaxation of Metacarpophalangal.

E)Non of the above.

  1. Which disorder is diagnosed by the presence of calcium pyrophosphate is synovial fluid:

    1. Chondro calcinosis. B)Gouty arthritis.

C)Psoriatic arthritis. D)Psoriatic arthritis. E)O.A



  1. A patient present with B-Asthma mono neuritis multiplex-esoino phila.ANCA positive ; what is the most likely diagnosis :

  1. SLE.

  2. Wegner granulomatosis. C)Microscopic polyangiitis. D)Good pasture.

E)Currg-strass.



  1. Which of the statements isn't true according to myositis : A)Inclusion body myositis take a good prognosis.

  1. Helio trope rash is highly specific for dermato myositis.

  2. steroid is corner stone for treatment. D)Statin's can induced myositis.

E)Subcutanous calcification a frequent manifestation in juvenile dermato myositis.

  1. A disease modifying anti rheumatic drugs (DMARD) include all f the following except for :

    1. Salazo pyrine. B)Hydroxychloro quine. C)Colchicine.

D)Methotrexate E)leflenamide

  1. All of the following are criteria for Behcet disease except for : A)Mouth ulcer's.

B)Arterial Anuyresm .ِ C)Hypopyron..
D)Pethergy test. E)Acne-like lesion



  1. All of the following are criteria for SLE A)Anti RNP.

B)Mouth ulcer's. C)ANA.
D)Photosensitivity. E)Leukopenia.



  1. One of the following deformities can't be caused by RA: A)Swan neck deformity.

  1. Genu valgua.

  2. Elbow flextion.

  3. Bouchard nodules.

  4. Z deformity of thumb.




  1. All of the following are indications for the treatment of Gouty arthritis except for: A)Chronic Gouty arthritis.

  1. Renal stones.

  2. Renal failure.

  3. Serum uric acid more than 8mg in men. E)All of the above.




  1. One of the following isn't a characteristic for spondylo arthropathy: A)Strong association with HLA-B27.

  1. Occasional Aortitis.

  2. Assocoation with chronic inflammatory bowel disease. D)Tendency for posterior uveitis.

E)Enthesitis.

  1. The isn't a cause of secondary sjogren: A)Reactive arthritis.

  1. SLE.

  2. Scleroderma.

  3. RA.

  4. Hypothyroctism.


  1. Differential diagnosis of sacroiliitis includes all of the following except for: A)Psoriatic.

B)Behcet disease. C)Aukylosing spondylitis. D)Reactive arthritis.
E)Chron disease.

  1. Boutonniere deformity is seen in:

    1. RA.

    2. Psoriatic arthritis. C)Reactive arthritis.

D)Ostco arthritis. E)Tenosynovitis of haud.



  1. All of the following are ANCA associated vascuilitis except for: A)Microscopic poly angiitis.

B)Churg-strauss vascuilitis. C)Kawasaki syndrome.

  1. Wegner gramulomatosis.

  2. All of the above.

19. A healty patient who is HLA-B27 is most likely to develop ONE of the following. a- psoratic arthritis


b- enteropathic spondylitis c- gonococcal arthritis

  1. Reiters disease

  2. ankylosing spondylitis

22. All the following are true about gout except:


a- Is caused by deposition of monosodium urate monohydrate crystals in the joints. b- It is an asy,mmetric arthritis.

  1. Can be caused by thaiazide diuretics.

  2. It is commoner in females than males 4:1.

  3. Attack of gout can be triggered by dehydration. f-

g- 30. Rheumatoid factor is positive in all the following diseases except: h- a.- Rheumatoid arthritis

  1. b- dermatomyocytis

  2. c- ankylosying spondylitis

  3. d- dicoid lupus erythematosis

  4. e- mixed connective tissue diseases.

53. A-25- year old man presents with urethritis, painful swollen left knee and conjunctivitis.


ONE of the following is most likely diagnosis. a- SLE

  1. Gonococcal arthritis

  2. Gout

  3. Reiter's syndrome

  4. Ankylosising spondylitis




  1. All the following are true about rheumatoid arthritis except. a- it is chronic disease, but curable.

b- it is commonly associated with positive rheumatoid factor c- antimalarial treatment is one of the lines of management. d- the patients with the disease are liable to infection
e- this disease may affect the patients functionally.



  1. All the following are true about uric acid metabolism except. a- 2/3 of body uric acid pool is dietary in origin

b- 2/3 is from endogenous purine metabolism c- 2/3 of uric acid is excreted by the kidney
d- serum uric acid is increased in polycythemia rubra vera
f- serum uric acid is increased in eclampsia of pregnancy.

64- All the following are poor prognostic signs in scleroderma except. a- old age of onset.


b- limited skin involvement. c- high ESR

  1. renal involvement

  2. pulmonary hypertension

65. Pathergy test is positive in one of the following diseases. a- Behcet's syndrome

  1. Kawasaki disease

  2. erythema multiforme d- osteoarthritis

e- rheumatoid arthritis

67. A 50-year old woman has pain in her fingers on exposure to cold, arthralgia, and difficulty in swallowing solid food.


The most useful One test to make a definitive diagnosis is a- rheumatoid factor
b- anti-nuclear antibody c- ECG
d- Blood urea and serum creatinin e- anti-mitochondrial antibody

92. ONE of the following is not a disease –modifing anti-rheumatoid arthritis drug. a- sulfasalazine



  1. NSAIDs

  2. methotrexate d- leflunamide

e- sodium aurothiomalate (Gold)
98. All the following are true regarding the pathogenesis of lupus erythematosis except. a- the exact cause is unknown.

  1. It is a chronic inflammatory disease.

  2. the basic pathological unit is vasculitis

  3. it is due to type I hypersensitivity reaction.

  4. genetic and environmental factors may play a role in the disease.

100. Repeated multiple mouth ulcers are seen in the following conditions EXCEPT: a- Behcet's disease.
b- Systemic lupus erythematosus. c- Herpes simplex virus infection. d- Ankylosing spondylitis.
e- Mental stress.



    1. 70-year-old man with 3 months headache, stiffness, low grade fever, jaw claudication, and amuresiss fugax, his ESR is 100, all of the following statements are true regarding this condition, except:

      1. Increased risk of permenant blindness

      2. Tongue claudicaiton

      3. Weight loss

      4. Drug therapy can only be started after tissue biospy

      5. Dramatic response to steroids





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