Systematic Review of Gossypol/at-101 in Cancer Clinical Trials



Download 2,34 Mb.
Pdf ko'rish
bet16/23
Sana04.05.2023
Hajmi2,34 Mb.
#934966
1   ...   12   13   14   15   16   17   18   19   ...   23
Bog'liq
Systematic Review of GossypolAT-101 in Cancer Clin

a
) and outcome (
b
). (
a

The diagram illustrates the total number of conducted clinical trials as a circle. The numbers in the 
four sections correspond to the number of studies performed in each case. The light blue sections 
represent the proportion of studies performed with gossypol/AT-101 as single agent, light orange 
sections represent the proportion of combined therapies (gossypol/AT-101 and standard anticancer 
protocols). Each section is further subdivided by study phase and contains colored boxes with the 
corresponding references in brackets. Each color represents one of the study outcomes defined in 
(
b
). (
b
) The bar divides the study outcomes into six categories. Each of the six different categories 
contains the number of studies performed and is color-coded according to the study outcome. 
After a long period of testing of gossypol/AT-101 against different tumor entities as 
monotherapy or in combination with other anti-tumor drugs, Song et al. recently 
demonstrated an encouraging success regarding the treatment of patients with 
gastroesophageal carcinoma. In contrast to other investigations, where the benefits of the 
treatment were observed either in some subjects or in a special sub-group of patients, there 
are at least three major differences in this new study. For the first time, the researchers 
focused on cancer stem cells in addition to anti-apoptotic pathways, which often cause 
therapy residence. Second, besides the standard chemotherapeutic regimes of 
Figure 4.
Graphical representation of the results of reviewed studies in cancer clinical trials analyzing
the administration of gossypol/AT-101 as a single agent or in combination with standard anticancer
treatments. The pie chart is stratified according to study design (
a
) and outcome (

Download 2,34 Mb.

Do'stlaringiz bilan baham:
1   ...   12   13   14   15   16   17   18   19   ...   23




Ma'lumotlar bazasi mualliflik huquqi bilan himoyalangan ©hozir.org 2024
ma'muriyatiga murojaat qiling

kiriting | ro'yxatdan o'tish
    Bosh sahifa
юртда тантана
Боғда битган
Бугун юртда
Эшитганлар жилманглар
Эшитмадим деманглар
битган бодомлар
Yangiariq tumani
qitish marakazi
Raqamli texnologiyalar
ilishida muhokamadan
tasdiqqa tavsiya
tavsiya etilgan
iqtisodiyot kafedrasi
steiermarkischen landesregierung
asarlaringizni yuboring
o'zingizning asarlaringizni
Iltimos faqat
faqat o'zingizning
steierm rkischen
landesregierung fachabteilung
rkischen landesregierung
hamshira loyihasi
loyihasi mavsum
faolyatining oqibatlari
asosiy adabiyotlar
fakulteti ahborot
ahborot havfsizligi
havfsizligi kafedrasi
fanidan bo’yicha
fakulteti iqtisodiyot
boshqaruv fakulteti
chiqarishda boshqaruv
ishlab chiqarishda
iqtisodiyot fakultet
multiservis tarmoqlari
fanidan asosiy
Uzbek fanidan
mavzulari potok
asosidagi multiservis
'aliyyil a'ziym
billahil 'aliyyil
illaa billahil
quvvata illaa
falah' deganida
Kompyuter savodxonligi
bo’yicha mustaqil
'alal falah'
Hayya 'alal
'alas soloh
Hayya 'alas
mavsum boyicha


yuklab olish