Dorivor o’simliklar virus kasalliklari Marmarak Salvia sclarea L misolida

S. officinalis has been used as a traditional remedy against diabetes in many countries and its glucose-lowering affects have been demonstrated in animal studies. In a study, it was found that methanolic extracts of S. officinalis significantly decreased serum glucose in type I diabetic rats without affecting pancreatic insulin production. An aqueous extract of S. officinalis has been found to exhibit insulin-like activities.

In a study, drinking of sage tea (common sage) (300 ml, twice a day) showed increase in antioxidant defenses and improved the lipid profile, without causing any hepatotoxicity or inducing any adverse affects such as changes in blood pressure, heart rate, and body weight, which may indirectly improve the diabetic condition.Tea infusions of S. officinalis have shown to be as effective as metformin, which is an oral anti-diabetic drug used for the treatment of type II diabetes, and act by reducing liver glucose production as well as increasing the action of insulin. In many studies, the sage extract was found to have hypoglycemic effect in diabetic animals and further researches need to consider the additional therapeutic effects of this plant in future.

DIABET

Ko'p mamlakatlarda qandli diabetga qarshi an'anaviy vosita sifatida foydalanilgan va glyukoza kamaytiradigan ta'sir hayvonlarni tadqiq qilishda qo'llanilgan . Bir tadqiqotda, S. officinalis metanolik ekstrakti I-toifa diabetik ratlarda pankreatik insulin ishlab chiqarishga ta'sir qilmasdan sarum glyukoza miqdorini sezilarli darajada kamaytirganligi aniqlandi. S. officinalisning suvli ekstrakti insulinga o'xshash faoliyatni namoyish etish uchun topildi.

Bir tadqiqotda, adaçayı çayının (umumiy shingil) (300 ml, kuniga ikki marta) ichish, antioksidant mudofaa o'sishini ko'rsatdi va lipid profilini yaxshilandi, hepatotoksisite sabab bo'lmasdan yoki qon bosimi, yurak urish tezligi, va tana og'irligi, bu diabetik holatni bilvosita yaxshilaydi [21]. S. officinalislarning choy infuziyalari II turdagi diabet kasalligini davolash uchun ishlatiladigan og'izdan piyodalarga dipopatik dori bo'lgan metformin kabi samarali ekanligi va jigar glyukoza ishlab chiqarishini qisqartirish va insulin ta'sirini kuchaytirish orqali ta'sir ko'rsatdi. ] Ko'pgina tadqiqotlar shuni ko'rsatdiki, shox o'simligining diabetik hayvonlarda hipoglisemik ta'sirga ega bo'lishi va kelgusidagi tadqiqotlarda bu o'simlikning kelajakdagi terapevtik ta'sirini hisobga olish kerak.

CANCER

Cancer is characterized by abnormal growth of cells which tend to proliferate in an uncontrolled way, and in some cases, spread to other parts of the body. The important factor in proliferating and spreading of cancer cells is the ability of tumors to produce a large number of new blood vessels, which is known as angiogenesis. Most primary solid tumors are dependent on angiogenesis for survival, growth, invasion, and metastasis. It was found in a study that S. officinalis extract at pharmacological concentrations inhibits angiogenesis in vivo, which could be a novel starting point for the development of a new anti-angiogenic drug. Ursolic acid found in sage effectively inhibits angiogenesis, invasion of tumor cells, and metastasis, and suppresses the lung colonization of B16 melanoma cells .

SARATON

Saraton xujayralari g'ayritabiiy o'sishi bilan ajralib turadi, ular nazoratsiz ravishda ko'payishadi va ba'zi hollarda tananing boshqa qismlariga tarqaladi . Saraton xujayralarining tarqalishida va tarqalishida muhim omil - o'smalarning angiogenez deb nomlanadigan ko'plab yangi qon tomirlarini ishlab chiqarish qobiliyati. Asosiy qattiq shishlarning ko'pchiligi yashash, o'sish, invaziya va metastaz uchun angiogenezga bog'liq. Ichki dori konsentrasiyalaridagi S. officinalis ekstrakti in vivo jonli angiogenezni inhibe qiladigan, bu esa yangi piyodalarga-angiogen preparatni ishlab chiqish uchun yangi boshlang'ich nuqta bo'lishi mumkin bo'lgan bir ishda topilgan . Shakarda topilgan ursolik kislota angiogenezni, o'simta hujayralarining ishg'ollanishini va metastazni samarali tarzda inhibe qiladi va jonli B16 melanoma hujayralarining o'pka kolonizatsiyasini bostiradi.

Kolorektal saraton (CRC) keng tarqalgan saraton turi va G'arb jamoalarida o'limning muhim sababi hisoblanadi. U odatdagi kolon hujayralarini proliferatsiya qiluvchi hujayralarga uzatuvchi genetik va epigenetik o'zgarishlar bilan rivojlanadi. [38] Ushbu ishda xun tarkibidagi moddalar epigenetik holatni o'zgartirishi mumkinligini ko'rsatdi. Ko'pgina oziq-ovqat o'simliklari bioaktiv birikmalarga boy va antikanser xususiyatlarga ega ekanligini ko'rsatdi. Ichuvchi adaçayı (S. officinalis) o'simlik choyining ta'siri, sıçanlarda kolonna saratonini oldini olish uchun o'rganildi.

Colorectal cancer (CRC) is a common type of cancer and a significant cause of mortality in Western societies. It develops by genetic and epigenetic alterations which transfer normal colon cells to proliferating cells. This study has shown that dietary compounds can change the epigenetic status. Many food plants are rich in bioactive compounds and have shown to possess anticancer properties. The effect of drinking sage (S. officinalis) herbal tea was studied on the prevention of colon cancer in rats.

Salvia libanotica (Lebanese sage) is one of the largely used sage species in traditional medicine, which has been used for many years to cure diseases such as abdominal pains, headaches, indigestion, and heart disorders. The oil extract of this species was shown to possess strong antimicrobial and antitumor effects. The components of Lebanese sage essential oil were identified by gas chromatography, and three of the components which contain on average 9.1% camphor (Ca), 1.3% α-terpineol (Te), and 1.1% linalyl acetate (Ly) were found to be responsible for the oil's antibacterial, antifungal, anti-inflammatory, and antitumor effects

Salvia libanotica (Livan shoxlari) ko'p yillar davomida qorin og'rig'i, bosh og'rig'i, ovqat hazm qilish va yurak kasalliklari kabi kasalliklarni davolash uchun qo'llanilgan an'anaviy tibbiyotda ishlatiladigan katta miqdorda ishlatiladigan shoxlarning bir turi. Ushbu turdagi yog 'ekstrakti kuchli antibiotiklar va antitumor ta'sirlarga ega ekanligini ko'rsatdi. [2]

The medicinal plant species Salvia sclarea (L.) – clary sage is important for the production of raw materials (drugs) necessary for the pharmaceutical and food industry.

Dori-darmon o'simliklarining turlari Salvia sclarea (L.) - aniq shaxta uchun muhim ahamiyatga ega farmatsevtika, (preparatlar) ishlab chiqarish va oziq-ovqat sanoati uchun zarur bo'lgan xom ashyodir.