UniProt: the Universal Protein



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Contacting UniProt
help@uniprot.org
www.uniprot.org
EMBL-EBI 
Wellcome Trust Genome Campus 
Cambridge, CB10 1SD, UK
Phone: +44 (0)1223 494444 
SIB Swiss Institute of Bioinformatics 
CMU - 1 rue Michel Servet
CH-1211 Geneva 4
Switzerland 
Phone: +41 22 379 50 50
Protein Information Resource 
Georgetown University Medical 
Center 
3300 Whitehaven Street NW 
Suite 1200 
Washington, DC 20007 
USA
Phone: +1 202 687 1432 
on the quality of annotation in the form of evidence attribution to 
experimental and computational data.
The UniRef databases
provide clustered sets of sequences from 
UniProtKB and selected UniParc records to provide complete coverage 
of sequence space at several resolutions. UniRef90 and UniRef50 yield 
a database size reduction of approximately 40% and 65%, respectively, 
providing significantly faster sequence searches. 
UniParc
is the most comprehensive publicly accessible non-redundant 
protein sequence database available, providing links to all underlying 
sources and versions of these sequences. You can instantly find out 
whether a sequence of interest is already in the public domain and, if not, 
identify its closest relatives.
UniMES
is a repository specifically for metagenomic and environmental 
data. 
EMBL-EBI
EMBL-EBI
EMBL-EBI
UniRef100
UniRef90
UniRef50
Metagenomic
and environmental
sample sequences
UniProtKB
Protein Knowledgebase
UniParc
- Sequence archive 
Current and obsolete sequences
ENA/GenBank/DDBJ, Ensembl, other sequence resources
UniMES
UniRef
Sequence clusters
Reviewed 
Manual annotation
UniProtKB/Swiss-Prot
Unreviewed
Automatic annotation
UniProtKB/TrEMBL
Sources and flow of data for UniProt’s component databases.

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