The ministry of education named after mirzo ulugbek national

The work of aim and objectives: This thesis the aim F-18, F-37 izoxinolin alkaloidi the rats in the aorta blood-vessels , smooth muscle cells , ion channels relaksant ta‘secret mechanisms o’rga to use is.

To achieve the ultimate goal the following tasks have been identified.

- The rat aorta to kcl and reduced activity of the drug in the blood vessels called into doses that have been associated with fenilefrin determine the effect of alkaloidi.

- F-18, f-37 izoxinolin alkaloidi their relaksant ta’ mystery in providing smooth muscle cells (SMH) world plazmalemmasidagi determine the location of ion channels .Statistical analysis of the results obtained.

- F-18, f-37 izoxinolin alkaloidi their relaksant ta’ mystery in providing sarkoplazmatik retikulum ca+2 determine the location of the carrier system.