Таълим вазирлиги ўзбекистон республикаси соғЛИҚни сақлаш

Table 
The dynamics of cellular immunological parameters in CGN (M ± m) 
Indicators 
Control group, 
n=25 
Illness children, n=25 
Before treatment
CGN, n=25 
1-group
Traditional 
treatment, 
n=20, 2-group
СД3, % 
56,21±0,98 
36,50±1,48* 
43,52±1,21# 
СД4 % 
34,50±1,40 
13,00±1,35* 
16,00±1,47# 
СД8, % 
18,64±0,49 
7,21±0,75* 
13,20±1,57 
СД19, % 
11,16±0,73 
25,21±0,44* 
21,14±0,65 
LNK16, % 
11,44±0,53 
7,08±0,84* 
7,00±0,67 
PhAN,% 
50,50±1,11 
29,88±1,59* 
33,04±0,34# 
CIC,un.op.den
s 
0,002±0,004 
0,12±0,003* 
0,075±0,008 
Note: * - reliability of differences compared with the healthy group 
(P<0,001-0,01-0,05); # - significant differences between groups 1 and 2 (P<0,001-
0,01-0,05). 
After immune dynamics (3-6 months) in patients who received traditional 
treatment, showed improvement of immunological parameters, expressed in a 
significant increase in the relative content of CD3, CD4, CD8, PhAN, (P <0,01-
0,05), a significant decrease in CIC and concentration (P <0,01) compared to the 
group before treatment.
Conclusions 
1. Children in the nephrotic form of CGN immunopatological shifts are 
characterized by deficient cellular immunity in the form of a reduction of CD3, 
CD4, CD8, LNK16, FhAN, an increase in the number of CD19 and the 
concentration of the CIC, which are stored in the remission and can serve as a 
criterion of immunodiagnostics. 
2. Deficient of the cellular immunity in children with nephrotic form of 
chronic glomerulonephritis to recommend immunocorrection therapy in complex 
treatment of that patient. 
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