Schneiderman Prelims Vol-I. qxd

METABOLIC
Congenital neutropenia
Cyclic neutropenia
Cystic fibrosis
Fabry’s disease 
Ghatan p.76, 2002, Second Edition
Fucosidosis type III
Hunter’s syndrome – X-linked recessive; macrocheilia;
reticulated 2–10 mm skin-colored papules over scapulae,
chest, neck, arms; MPS type II; iduronate-2 sulfatase deficiency;
lysosomal accumulation of heparin sulfate and dermatan
sulfate; short stature, coarse facies, macroglossia, clear
corneas (unlike Hurler’s syndrome), progressive
neurodegeneration, communicating hydrocephalus, valvular
and ischemic heart disease, lower respiratory tract infections,
adenotonsillar hypertrophy, otitis media, obstructive sleep
apnea, diarrhea, hepatosplenomegaly, skeletal deformities
(dysostosis multiplex), widely spaced teeth, dolichocephaly,
deafness, retinal degeneration, inguinal and umbilical hernias
Ped Derm 21:679–681, 2004
Hurler’s syndrome 
Rook p.3140, 1998, Sixth Edition; Oral Surg
32:46–57, 1971
Hypothyroidism 
NEJM 283:101, 1970
Lesch–Nyhan syndrome – X-linked recessive;
hypoxanthineguanine phosphoribosyltransferase deficiency;
self-mutilation; biting of lower lip 
AD 94:194–195, 1966
Vitamin B
1
and B
2
deficiencies – red lips, angular cheilitis
Ped Derm 16:95–102, 1999; JAAD 15:1263–1274, 1986
NEOPLASTIC
Actinic cheilitis 
J Derm Surg Oncol 7:289–295, 1981
Epstein–Barr virus associated lymphoproliferative lesions
BJD 151:372–380, 2004
Granular cell schwannoma – linear plaque 
AD 121:1197–1202,
1985
Kaposi’s sarcoma 
Rook p.3130, 1998, Sixth Edition
Leukemic macrocheilia – acute myelogenous leukemia
BJD 151:1102, 2004; JAAD 14:353–358, 1986
Leukoplakia
Lymphoma – T-cell lymphoma mimicking Crohn’s disease
Oral Oncol 29B:225–230, 1993
Lymphomatoid granulomatosis (angiocentric lymphoma) –
presenting as angioedema 
Postgrad Med J 68:366–368, 1992
Melanoma – desmoplastic melanoma of lip; induration and
edema 
JAAD 47:863–868, 2002
Neurofibroma 
Rook p.3140, 1998, Sixth Edition
Squamous cell carcinoma
Verrucous carcinoma – oral florid papillomatosis of the lip
BJD 151:727–729, 2004