Schneiderman Prelims Vol-I. qxd

parts 
AD 113:161–165, 1977; Medicine 34:381–430, 1955
Hepatic disease, including primary biliary cirrhosis
Hyperthyroidism – patchy hyperpigmentation or diffuse
Addisonian hyperpigmentation sparing oral mucosa
JAAD 26:885–902, 1992
Kwashiorkor
Liver disease, chronic – diffuse muddy gray hyperpigmentation;
primary biliary cirrhosis 
Rook p.2725, 1998, Sixth Edition
Lysosomal storage disease – anterior and posterior dermal
melanocytosis in Hurler’s disease, GM, gangliosidosis type 1,
Niemann–Pick disease, Hunter’s disease, alpha-mannisidosis
AD 139:916–920, 2003
Malabsorption – Addisonian hyperpigmentation or local
pigmentation of face, neck, trunk 
Rook p.1784,2653, 1998,
Sixth Edition
Malnutrition
Megaloblastic anemia 
JAAD 12:914–917, 1985
Myxedema
Nelson’s syndrome – post-adrenalectomy diffuse
hypermelanosis 
Ann Intern Med 52:560–569, 1960
Niemann–Pick disease – acid sphingomyelinase; diffuse
pigmentation, especially of face 
Rook p.1778–1779, 1998,
Sixth Edition
Ochronosis – generalized hyperpigmentation with accentuation
over cheeks, forehead, axillae and genitalia, buccal mucosa,
nails 
Rook p.2649, 1998, Sixth Edition
Pellagra – niacin deficiency; Addisonian hyperpigmentation;
accentuated on face, hands 
Rook p.1783, 1998, Sixth Edition
Pernicious anemia (vitamin B
12
deficiency) – diffuse or
mottled hyperpigmentation of face, hands, feet, and scrotum
Cutis 71:127–130, 2003; J Dermatol 28:282–285, 2001;
JAAD 15:1263–1274, 1986; AD 12:896–899, 1986
Porphyria cutanea tarda 
Rook p.2590, 1998, Sixth Edition;
variegate porphyria 
Rook p.2586–2587, 1998, Sixth Edition;
hepatoerythropoietic porphyria 
AD 116:307–313, 1980
Renal failure, chronic – muddy brown hyperpigmentation
Rook p.1782,2730, 1998, Sixth Edition
Scurvy – Addisonian 
Rook p.1784, 1998, Sixth Edition
Sprue 
Ghatan p.6, 2002, Second Edition
Vitamin A deficiency 
JAAD 41:322–324, 1999
Whipple’s disease 
Rook p.2654, 1998, Sixth Edition
Wilson’s disease