Schneiderman Prelims Vol-I. qxd

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A CLINICIAN’S GUIDE TO DERMATOLOGIC DIFFERENTIAL DIAGNOSIS, VOLUME 1
Schneiderman page 200-300.qxd 5/16/2006 6:49 PM Page 238

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Mukamel syndrome – autosomal recessive; premature graying
in infancy, lentigines, depigmented macules, mental retardation,
spastic paraparesis, microcephaly, scoliosis 
Bolognia, p.859,
2003
Myotonic dystrophy – hypopigmented hair 
Ghatan p.70, 2002,
Second Edition; Rook p.2964, 1998, Sixth Edition
Piebaldism
Pierre–Robin syndrome – hypopigmented hair 
Ghatan p.70,
2002, Second Edition
Premature canities, palmoplantar hyperhidrosis, premolar
hypodontia
American J Human Genetics 2:240–263, 1950
Progeria (Hutchinson–Gilford syndrome) – hypopigmented
hair 
Ghatan p.70, 2002, Second Edition; Rook p.2964, 1998,
Sixth Edition
Pseudocleft of upper lip, cleft lip-palate, and hemangiomatous
branchial cleft – canities 
Plast Reconstr Surg 83:143–147, 1989
Pseudocleft of the upper lip (or cleft lip/palate), linear cutaneous
lesions on the lateral neck (ranging from bronchial clefts to
epidermal nevi) and cervical thymus 
Am J Med Genet
27:943–951, 1987
Rothmund–Thomson syndrome 
Rook p.2964, 1998,
Sixth Edition
Seckel’s syndrome (bird-headed dwarfism) – autosomal
recessive; hair sparse and prematurely gray, growth retardation,
beak-like nose, large eyes, skeletal defects 
Am J Med Genet
12:7–21, 1982
Sialic acid storage disease – silver hair, coarse facial features,
hepatosplenomegaly 
AD 135:203–208, 1999
Sensory neurodeafness with premature graying of the hair
Laryngol Otol 73:355–367, 1959
Sudden whitening of hair
Tay syndrome – autosomal recessive, growth retardation,
triangular face, cirrhosis, trident hands, premature canities,
vitiligo 
Bolognia p.859, 2003
Treacher Collins syndrome – hypopigmented hair 
Ghatan
p.70, 2002, Second Edition
Unusual facies, vitiligo, canities, progressive spastic paraplegia
Am J Med Genet 9:351–357, 1981
Vogt–Koyanagi–Harada syndrome 
Ann DV 127:282–284, 2000
Waardenburg syndrome
Werner’s syndrome (pangeria) – graying of temples in teenage
years progressing to canities
Rook p.2964, 1998, Sixth Edition;
Medicine 45:177–221, 1966
TRAUMA
Physical trauma – hypopigmented hair 
Ghatan p.70, 2002,
Second Edition
Radiation therapy – hypopigmented hair 
Rook p.2964, 1998,
Sixth Edition