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[Encyclopedia of Differential Diagnosis in Dermatology] Paul Schneiderman, Marc E. Grossman - A Clinician\'s Guide to Dermatologic Differential Diagnosis, Volume 1 The Text (Encyclopedia of Differential Diagnosis in D

EYES, RED, AND RASH
195
Schneiderman page 100-200.qxd 5/16/2006 6:49 PM Page 195


Chlamydia trachomatis
Cobra spray
Coccidioidomycosis – episcleritis with erythema nodosum 
Rook
p.3006, 1998, Sixth Edition
Conjunctivitis
Adenoviral pharyngoconjunctival fever – type 3
Chlamydia trachomatis
Coccidioidomycosis
Epidemic keratoconjunctivitis – adenovirus type 8
Mumps interstitial conjunctivitis
Pharyngoconjunctival fever – adenovirus type 3
Secondary syphilis – iris roseata
Streptococcal
Tuberculous interstitial (parenchymal) conjunctivitis
Cowpox (feline orthopoxvirus) – conjunctivitis, keratitis 
JAAD
49:513–518, 2003
Cryptococcosis – in AIDS; conjunctivitis 
Eye and Skin Disease,
pp.471, Lippincott, 1996
Cysticercosis 
JAAD 25:409–414, 1991
Dacryocystitis (infection of the lacrimal sac) – acute or chronic
Dengue hemorrhagic fever – conjunctival suffusion 
Clin Inf Dis
36:1004–1005,1074–1075, 2003; JAAD 46:430–433, 2002;
Tyring p.476, 2002
Dermatophytosis 
Ghatan p.173, 2002, Second Edition
Diphtheria
Dirofilariasis, subcutaneous (migratory nodules) – eyelid,
scrotum, breast, arm, leg, conjunctiva 
JAAD 35:260–262, 1996
Ebola virus 
Tyring p.423, 2002
Echovirus 16
Ehrlichiosis – conjunctivitis, morbilliform eruption, transient
erythema, petechiae, purpura, TSS/Kawasaki’s like eruption
Ann Intern Med 120:736–743, 1994
Epidemic typhus (
Rickettsia prowazeki ) (body louse) – pink
macules on sides of trunk, spreads centrifugally; flushed face
with injected conjunctivae; then rash becomes deeper red, then
purpuric; gangrene of finger, toes, genitalia, nose 
JAAD
2:359–373, 1980
Ethmoid sinusitis with periorbital cellulitis
Filariasis
Filoviruses – Marburg and Ebola virus; transient morbilliform
rashes, purpura, red eyes 
JAAD 49:979–1000, 2003
Fusarium – of sinuses; nasal erythema with conjunctivitis 
JAAD
47:659–666, 2002
Gonorrheal conjunctivitis – profuse purulent discharge; swollen
hemorrhagic eyelids 
Rook p.2998, Sixth Edition
Hantavirus hemorrhagic fever 
Tyring p.425,435, 2002
Herpangina – conjunctivitis 
Curr Prob Derm VIII:41–96, 1996
Herpes simplex – follicular conjunctivitis, episcleritis, keratitis,
dendritic ulcer, anterior uveitis, central retinal vein occlusion,
eczema herpeticum, periocular zosteriform eruption 
J Virol
75:5069, 5075, 2001; Medicine 78:395–409, 1999; Arch
Ophthalmol 107:1155–1159, 1989; Nephron 50:368–370, 1988;
Am J Med Sci 277:39–47, 1979; Kaposi’s varicelliform eruption
Herpes zoster – episcleritis, scleritis, keratitis 
Rook p.2992,3006,
1998, Sixth Edition; J Laryngol Otol 100:337–340, 1986
Histoplasmosis
Infectious mononucleosis (Epstein–Barr virus) – conjunctivitis,
keratitis, uveitis, choroiditis, retinitis, papillitis 
Clin Inf Dis
31:184–188, 2000
Jellyfish envenomaton
Leishmaniasis – 
Leishmania major uveitis Clin Inf Dis
34:1279–1280, 2002
Leprosy – lepromatous with infiltration of corneal nerves leading
to anesthesia, infection, blindness 
Rook p.1225, 1998,
Sixth Edition; lepromatous leprosy deposits causing keratitis,
iridocyclitis, iris atrophy 
Rook p.1225, 1998, Sixth Edition;
erythema nodosum leprosum with uveitis, edema, and
hyperemia resulting in painful red eye 
JAAD 51:416–426, 2004;
AD 138:1607–1612, 2002; Rook p.1227,1229, 1998,
Sixth Edition
Leptospirosis 
J Clin Inf Dis 21:1–8, 1995
Loiasis – 
Loa loa; Chrysops (deer fly, horse fly, mangrove fly) –
adult worms in conjunctiva with unilateral palpebral edema 
AD
108:835–836, 1973
Lyme disease – conjunctivitis, episcleritis, keratitis, iridocyclitis
Adv Int Med 46:247–275, 2001; NEJM 321:586–596, 1989; AD
120:1017–1021, 1984
Lymphogranuloma venereum 
JAAD 41:511–529, 1999
Measles
Meningococcal conjunctivitis and cellulitis 
Pediatrics
60:104–106, 1977; meningococcemia with orbital hemorrhage
and DIC – periorbital edema and subconjunctival hemorrhage
Eye 16 (2):190–193, 2002; meningococcemia – conjunctivitis,
conjunctival petechiae; chronic meningococcemia –
conjunctivitis, iritis, retinitis 
BJD 153:669–671, 2005
Microsporidial conjunctivitis in HIV 
JAMA 275:1545, 1996
Millipede secretions – red eyes and mahogany pigmentation
Cutis 67:452, 2001; periorbital edema, periorbital mahogany
hyperpigmentation, conjunctivitis, keratitis 
JAAD 50:819–842,
2004
Molluscum contagiosum – chronic conjunctivitis and superficial
punctate keratitis 
Cutis 60:29–34, 1997
Moraxella osloensis
Murine typhus (
Rickettsia typhi ) – conjunctivitis MMWR
52:1224–1226, 2003
Mycobacterium africanum (Mycobacterium tuberculosis
complex) 
Mycobacterium bovis – conjunctivitis in milkmaids JAAD
43:535–537, 2000
Mycobacterium kansasii – red nodule of bulbar conjunctivum
BJD 152:727–734, 2005
Mycobacterium tuberculosis – lupus vulgaris; starts as
red–brown plaque, enlarges with serpiginous margin or as
discoid plaques; apple-jelly nodules; conjunctival involvement
with friable nodules which ulcerate 
Int J Dermatol 26:578–581,
1987; Acta Tuberc Scand 39 (Suppl 49):1–137, 1960;
papulonecrotic tuberculid – dusky red crusted or ulcerated
papules occur in crops; associated with phlyctenular
conjunctivitis 
Rook p.1199, 1998, Sixth Edition; Int J Dermatol
30:487–490, 1991; phlyctenular conjunctivitis with lichen
scrofulosorum 
Ped Derm 17:373–376, 2000; AD Syphilol
29:398–407, 1934; tuberculomas of conjunctiva; Parinaud’s
oculoglandular syndrome – granulomatous conjunctivitis with
pre-auricular adenopathy 
Rook p.2999, 1998, Sixth Edition
Myiasis, ocular
North American blastomycosis
Onchocerciasis – corneal inflammation around dead
microfilariae leads to punctate keratitis, then sclerosing keratitis
or iridocyclitis and possible blindness 
AD 140:1161–1166, 2004;
Cutis 72:297–302, 2003; JAAD 45:435–437, 2001; Cutis
65:293–297, 2000; AD 133:381–386, 1997
Orf 
Am J Ophthalmol 97:601–604, 1984
Pappataci fever
Paracoccidioidomycosis – conjunctival lesions 
Rook p.1370,
1998, Sixth Edition
Paragonimiasis – cold abscesses of conjunctivae 
Rev Ecuator
Hig Med Trop 36:69–82, 1979

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