Schneiderman Prelims Vol-I. qxd

INFILTRATIVE DISEASES
Langerhans cell histiocytosis – cutaneous findings include crops
of red–brown or red–yellow papules, vesicopustules, erosions,
scaling and seborrheic dermatitis-like papules, petechiae,
purpura, solitary nodules, bronze pigmentation, lipid infiltration
of the eyes, white plaques of the oral mucosa, onycholysis, and
onychodystrophy 
Curr Prob Derm VI Jan/Feb 1994; Clin Exp
Derm 11:183–187, 1986; JAAD 13:481–496, 1985; purpuric
papules in the neonate; masquerading as lichen aureus
Ped
Derm 8:213–216, 1991; Letterer-Siwe disease JAAD
18:646–654, 1988; purpuric vesicles JAAD 37:314–317, 1997
INFLAMMATORY DISORDERS
Hidradenitis suppurativa
Sarcoid – dermatitis-like lesions in children 
Clin Exp Dermatol
15:60–62, 1990; JAAD 5:566–570, 1981
METABOLIC
Acrodermatitis enteropathica – hands, feet, anogenital region,
periorificial, palmar flexures 
Curr Prob Derm 10:41–92, 1998;
chronic zinc deficiency – thickened brown dermatitis over
elbows, knees, knuckles, malleoli; lichenification with scaling
Rook p.2670, 1998, Sixth Edition; scrotal dermatitis Rook
p.3199, 1998, Sixth Edition
Ahistidinemia 
Curr Prob Derm 10:41–92, 1998
Asymmetric periflexural exanthem of childhood – unilateral
laterothoracic exanthem; dermatitic 
Ped Derm 19:461–462,
2002; Ped Derm 12:112–115, 1995
Biotinidase deficiency – combination of eczematous dermatitis
and neurologic symptoms 
Textbook of Neonatal Dermatology,
p.254, 2001
Carcinoid syndrome – pellagrous dermatitis (skin fragility,
erythema, and hyperpigmentation over knuckles), flushing,
patchy cyanosis, hyperpigmentation, telangiectasia, salivation,
lacrimation, abdominal cramping, wheezing, diarrhea 
BJD
152:71–75, 2005; AD 77:86–90, 1958; Am Heart J 47:795–817,
1954
Celiac disease – atopic dermatitis-like eruption 
Rook p.700,
1998, Sixth Edition; Lancet i:115–117, 1976
Cystic fibrosis, heterozygote 
Lancet i:990–991, 1976
Glucagonoma syndrome (necrolytic migratory erythema) –
scaling papules and plaques 
Skin and Allergy News Vol 32, July
2001, pp.1,59; The Clinical Management of Itching; Parthenon;
p.76, 2000; necrolytic migratory erythema also seen in gluten-
sensitive enteropathy, celiac disease, cirrhosis, hepatocellular
carcinoma, bronchial carcinoma, pancreatitis, hepatitis, and
inflammatory bowel disease
Hartnup’s disease 
Cutis 68:31–34, 2001; Ped Derm 16:95–102,
1999; presenting in adulthood Clin Exp Dermatol 19:407–408,
1994
Hereditary spherocytosis – dermatitis of the legs 
Ped Derm
20:427–428, 2003
Homocystinuria
Kwashiorkor – ‘enamel paint’ change; may resemble atopic
dermatitis on the face; red brown scaly plaques 
JAAD
52:S69–72, 2005; JAAD 21:1–30, 1989; in elderly, cracked skin
on lower abdomen and pretibial areas (geriatric nutritional
eczema) 
Rook p.2662, 1998,
Sixth Edition
Leiner’s disease 
Ghatan p.107, 2002, Second Edition;
Pediatrics 49:225–232, 1972
Liver disease, chronic (cirrhosis) – zinc deficiency; generalized
dermatitis of erythema craquele (crackled and reticulated
dermatitis) with perianal and perigenital erosions and crusts;
cheilitis, hair loss 
Rook p.2726, 1998, Sixth Edition; Ann DV
114:39–53, 1987
Malabsorption 
Br Med J ii:937–943, 1962; Q J Med 22:59–79,
1953; scrotal dermatitis Rook p.3199, 1998, Sixth Edition
Multiple carboxylase deficiency
Nephrotic syndrome – atopic dermatitis-like eruption 
Lancet
i:388–390, 1977
Pellagra – associated with celiac disease 
Yale J Biol Med
72:1518, 1999; scrotal dermatitis Rook p.3199, 1998, Sixth
Edition
Phenylketonuria – resembles atopic dermatitis 
JAAD
49:S190–192, 2003; Textbook of Neonatal Dermatology, p.255,
2001; Curr Prob Derm 10:41–92, 1998
Porphyria – erythropoietic protoporphyria – may be
confused with atopic dermatitis 
Eur J Pediatr 159:719–725,
2000; J Inherit Metab Dis 20:258–269, 1997; BJD 131:751–766,
1994; Curr Probl Dermatol 20:123–134, 1991; Am J Med
60:8–22, 1976
Prolidase deficiency – leg ulcers, dermatitis, xerosis 
BJD
144:635–636, 2001; JAAD 29:819, 1993
Prurigo of pregnancy – red papules 
Semin Derm 8:23–25, 1989