Schneiderman Prelims Vol-I. qxd

OF IMMUNE DYSFUNCTION
Allergic contact dermatitis – ‘black’ poison ivy due to oxidation of
resin 
JAAD 45:246–249, 2001; black lacquer dermatitis
Autoimmune blistering disorders – blisters with central
black dots
Dermatitis herpetiformis – black palmar lesions in purpuric
dermatitis herpetiformis 
Ped Derm 14:319–322, 1994
Dermatomyositis – epidermal necrosis
Graft vs. host disease – linear epidermal necrosis with black line
JAAD 1/94
Lupus erythematosus – lupus profundus; LE hypertrophicus et
profundus – verrucous brown–black plaque 
BJD 96:75–78, 1977
DRUG-INDUCED
Bismuth subsalicylate – black dots after oral ingestion of
Pepto-Bismol 
JAAD 37:489–490, 1997
Black hairy tongue – multiple antibiotics
Calcium gluconate, extravasated – linear and dot-like black
necrosis
Clofazamine – red to purple black 
Ghatan p.231, 2002, Second
Edition
Cyclophosphamide – black nails
Daunorubicin – black nails
Diltiazem – blue–black, photodistributed hyperpigmentation
JAAD 46:468–469, 2002
Gold salts – black nails 
Ghatan p.77, 2002, Second Edition
Hydroxychloroquine – blue–black pigmentation 
Ghatan p.231,
2002, Second Edition
Lanoprazole (proton pump inhibitor) – black tongue
AD 137:968–969, 2001; BJD 144:1293–1294, 2001
Methyldopa – black tongue 
AD 137:968–969, 2001;
AD 136:427–428, 2000
Minocycline – black galactorrhea 
AD 121:417–418, 1985; black
tongue 
AD 137:968–969, 2001; BJD 134:943–944, 1996;
AD 131:620, 1995; AD 121:417–418, 1985; black nails
Phenothiazine – black galactorrhea 
Rook p.3154, 1998, Sixth
Edition; AD 121:417–418, 1985
Zidovudine – black nails
EXOGENOUS AGENTS
Acupuncture beads
Anthralin staining
Black dermatographism – blackening of skin by metals; rubbing
of metal with zinc oxide, ferric oxide, pumice, titanium dioxide
Cutis 52:17–19, 1993; JAMA 121:485–490, 1943
Black tattoos – carbon (India ink), iron oxide, or logwood –
tattoo reaction 
JAAD 35:477–479, 1996
Cactus – dome shaped skin-colored papules with central black
dot 
Bolognia p.1477, 2003
Coal tar – black nails 
Ghatan p.77, 2002, Second Edition
Clothing dyes – released by sweating 
Rook p.2001, 1998, Sixth
Edition
Ebony workers – black nails
Foreign body, including foreign body granuloma; delayed
reaction to graphite pencil 
Cutis 42:199–201, 1988; black thorn
granuloma; sea urchin spines of the soles
Ink stain
Mercury-containing cosmetics – black nails
Photographic developing (methyl or p-methyl aminophenyl
sulfate hydroquinone) – black nails
Sea urchin spicules
Shoe polish – black nails
Silver nitrate – black nails
Skin graft – pseudomelanoma
Wine – black nails