Schneiderman Prelims Vol-I. qxd

VERRUCOUS LESIONS, PERIUNGUAL
685
Schneiderman page 600-722.qxd 5/16/2006 6:51 PM Page 685

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VERRUCOUS PLAQUES
AUTOIMMUNE DISEASES, AND DISEASES
OF IMMUNE DYSFUNCTION
Graft vs. host disease – columnar epidermal necrosis in
transfusion-associated chronic GVH 
AD 136:743–746, 2000
Lichen planus pemphigoides
Lupus erythematosus hypertrophicus – hypertrophic discoid
lupus erythematosus 
JAAD 9:82–90, 1983; Cutis 28:290–300,
1981; lupus profundus; LE hypertrophicus et profundus –
verrucous brown–black plaque 
BJD 96:75–78, 1977
Pemphigoid nodularis 
BJD 142:143–147, 2000
Pemphigoid vegetans – vegetating plaque 
JAAD 30:649–650,
1994; AD 115:446–448, 1979
Pemphigus erythematosis
Pemphigus vegetans – 1–2% of all cases of pemphigus;
Neumann type – bullae with small peripheral pustules evolve
into vegetative plaques; denuded areas develop after plaques
slough; Hallopeau type – pustules, not bullae, are the primary
lesions; verrucous plaques then develop; no denuded areas;
cerebriform tongue; spontaneous resolution not uncommon
Dermatol Clinics 11:429–452, 1993
Scleroderma – axillary verrucous pigmentation resembling
acanthosis nigricans 
Br Med J ii:1642–1645, 1966
CONGENITAL
Subepidermal calcified nodule in children – verrucous papule
Ped Derm 12:307–310, 1995
DEGENERATIVE
Diabetic neuropathy 
BJD 133:1011–1012, 1995
DRUG-INDUCED
Bleomycin 
JAAD 33:851–852, 1995
Halogenoderma – iodides – nasal congestion, conjunctivitis,
and a range of systemic symptoms or bromides with weakness,
restlessness, headache, ataxia, and personality changes; both
produce vegetative nodules or plaques often studded with
pustules; in iododerma, the verrucous plaques are often closer
to the eye, and in bromoderma, they are below the eye
Insulin – acanthosis nigricans-like changes due to insulin
injections 
AD 122:1054–1056, 1986
Lichen planus-like drug eruption