Scheme of Work Cambridge International as & a level

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bio scheme of work

Extension activity: Learners suggest the symptoms of diabetes insipidus, a condition that is due to an inability to secrete ADH, and Goodpastures syndrome, in which the body’s immune system attacks the basement membrane.

14.1.9 Describe the principles of cell signalling using the example of the control of blood glucose concentration by glucagon.

14.1.10 Explain how negative feedback control mechanisms regulate blood glucose concentration, with reference to the effects of insulin on muscle cells and liver cells and the effect of glucagon on liver cells.

14.1.11 Explain the principles of operation of test strips and biosensors for measuring the concentration of glucose in blood and urine, with reference to glucose oxidase and peroxidase enzymes.

Print and write on cards the sequence of events that occurs in control of blood glucose concentration. Shuffle the cards and ask the learners to arrange them in the correct sequence. The cards include the secretion and effects of insulin and glucagon. You could use animations to summarise this, such as: http://highered.mheducation.com/olcweb/cgi/pluginpop.cgi?it=swf::535::535::/sites/dl/free/0072437316/120109/bio48.swf::Action%20of%20Epinephrine%20on%20a%20Liver%20Cell (I)

Learners construct Venn diagrams to compare the features of insulin and glucagon. They should include the origin, mode of action, targets and functions of these hormones. (F)

Arrange learners into two teams. Host a debate in which learners from each team prepare a convincing argument to state why either one of the two methods of monitoring blood glucose concentration (glucose dipsticks and glucose biosensors) are preferable over the other.

Show some extended-answer responses to the same past paper question by three different learners, which achieve a range of marks. Learners decide why marks were awarded and how they could be improved. (F)

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